RNA-mediated events: chromosomal rearrangements and genomic rearrangements
(click to enlarge)
Excerpt: “Genome-wide DNA rearrangements are most exaggerated in ciliates, particularly in the model organism Oxytricha trifallax, which programs not only DNA deletion, but also total reorganization, through RNA-mediated events (Fang et al., 2012; Nowacki et al., 2008). ”
My comment: The RNA-mediated events that lead to DNA rearrangements were reported as:
Excerpt: “Previous work in Landweber’s lab—a 2012 publication in Cell and a 2008 paper in the journal Nature—showed that millions of noncoding RNA molecules from the previous generation direct this undertaking by marking and sorting the DNA pieces in the correct order.”
See my comments to the physorg.com site about the link from noncoding RNAs to DNA and chromosomal rearrangements.
Moving forward.
By John Hewitt on September 19, 2014 at 2:10 pm
Excerpt: “A final, cutting-edge new example highlights just how far some cells, and creatures, go to reconfigure their original “genome” throughout their lives. Every time a bizarre organism known as Oxytricha trifallax has a sexual encounter, it decrypts its own DNA and builds an entirely new version together with its partner. Strangely, there is no actual reproduction involved in these encounters, just exchange of DNA. Such extreme genetic rewiring is now just beginning to be witnessed, much less understood.”
My comment: Re: Oxytricha trifallax.
John Hewitt has done the unthinkable. He linked starvation in single-celled organisms with sexually differentiated cell types to RNA-mediated chromosomal rearrangements in humans via an accurate portrayal of what is known about the technology of human genome sequencing.
Conserved molecular mechanisms that link the epigenetic landscape to the physical landscape of DNA in the organized genomes of all species. Hewitt’s report shows what happens to evolutionary theory when biological facts are presented that link microbes to man. Simply put, theories that link mutations to the evolution of biodiversity are refuted by the fact that nutrient-dependent RNA-directed DNA methylation and amino acid substitutions link chromosomal rearrangements via the control of reproduction via species-specific pheromones.
The pheromones are metabolites of nutrients, which means that the physiology of reproduction is controlled by nutrient uptake, which leads to amino acid substitutions that are fixed in the genomes of all species via nutrient-dependent pheromone-controlled reproduction, not via mutations, natural selection or any other ridiculous theoretical explanation touted by evolutionary theorists.
Meanwhile, some researchers are still looking for genetic differences in cancer subtypes as if they did not know the subtypes result from RNA-mediated events, but lack of fixation of the amino acid substitutions that differentiate cell types. See for example: New visualization software uncovers cancer subtypes. The cancer subtypes consist of undifferentiated cell types due to mutations and lack of DNA repair via RNA-mediated events.
See also: Pulses of olfactory/pheromonal input
John Hewitt is the only science journalist I know who may have the knowledge required to link biophysically-constrained epigenetically-effected cell type differentiation via Luca Turin’s Molecular Vibration-Sensing Component in Human Olfaction from the de novo creation of olfactory receptor genes to the differentiation of cell types in species from microbes to man via conserved molecular mechanisms.
See also: Exploding genomes and chromosomal rearrangements via RNA-mediated events and 50+ other mentions of chromosomal rearrangements in my blog posts and 100+ posts about RNA-mediated events.
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6 MIN READ
0
Attacking Young Earth Creationists
5 MIN READ
0
80 years of causal analysis (1936 – 2016)
11 MIN READ
0
Energy-dependent polycombic ecological adaptation
21 MIN READ
0
Did evolution autophosphorylate your kinases? (3)
2 MIN READ
1
The natural success of RNAi and failed treatment
7 MIN READ
0
Virus-mediated hecatombic evolution
2 MIN READ
0
Hecatombic evolution via oncocers and oncohistones
9 MIN READ
0
Did evolution autophosphorylate your kinases? (2)
5 MIN READ
1
Nutrient-dependent autophagy
3 MIN READ
0
Nutrient-dependent pheromone-controlled autophagy (2)
6 MIN READ
0
Nutrient-dependent pheromone-controlled autophagy
3 MIN READ
0
Life is energy-dependent task management (2)
3 MIN READ
0
Life is energy-dependent task management
3 MIN READ
0
Hypothesis free pseudoscience vs facts (2)
5 MIN READ
0
Hypothesis free pseudoscience vs facts (1)
5 MIN READ
0
Chromatin: The structure of DNA (2)
8 MIN READ
0
Chromatin: The structure of DNA (3)
4 MIN READ
0
Chromatin: The structure of DNA
6 MIN READ
0
Hydrogen-atom energy in DNA base pairs
6 MIN READ
0
DNA repair via junk DNA (2)
5 MIN READ
0
Light energy-dependent active motifs
6 MIN READ
0
Light energy-induced base pair changes (2)
4 MIN READ
0
Light energy-induced base pair changes (1)
6 MIN READ
0
DNA repair via junk DNA (1)
5 MIN READ
0
How did the innate immune system evolve?
4 MIN READ
0
Energy-dependent cellular communication
3 MIN READ
0
Conserved biophotonic emissions
7 MIN READ
2
Antithetical conclusions (5)
4 MIN READ
0
Anthetical conclusions (2)
5 MIN READ
0
Co-evolution and co-speciation replace neo-Darwinian nonsense
4 MIN READ
0
Energy-dependent natural fluorescence and bioluminescence
2 MIN READ
0
Food supplement or licensed immunostimulant?
6 MIN READ
0
Q and A: Energy-dependent cell type differentiation
10 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity (2)
19 MIN READ
0
The Origin of Information (2)
6 MIN READ
0
Did “Nature” kill Steve Jobs? (3)
10 MIN READ
0
Funding the Human Genome Project-Write
2 MIN READ
0
Did “Nature” kill Steve Jobs? (2)
6 MIN READ
0
Did “Nature” kill Steve Jobs?
3 MIN READ
0
MicroRNAs and sexual orientation
8 MIN READ
0
RNA methylation, learning, memory and behavior,
< 1 MIN READ
0
Innate immunity and multiplexing
7 MIN READ
0
Amino acids and virus penetration
3 MIN READ
0
Major transition ends use of silly theories
5 MIN READ
0
RNA methylation
2 MIN READ
0
Model vs theory: Progress report!
8 MIN READ
0
The Mind’s Eyes (revisited)
10 MIN READ
0
RNA methylation, behavior, and disease
6 MIN READ
0
Energy-dependent RNA methylation (10)
4 MIN READ
0
Energy-dependent RNA methylation (7)
7 MIN READ
0
Energy-dependent RNA methylation (6)
9 MIN READ
0
Energy-dependent RNA methylation (3)
10 MIN READ
0
Energy-dependent RNA methylation (1)
6 MIN READ
0
Secular humanism and ecoterrorism
4 MIN READ
0
War Games: False Flag Terrorism
5 MIN READ
0
Magic, Miracle, or Molecular Mechanism (3)
2 MIN READ
0
Energy-dependent creation and entropy
4 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (4)
5 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (3)
5 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (2)
7 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics
9 MIN READ
0
Wasted Templeton Funding (4)
3 MIN READ
0
RNA splicing, genetic variation, and disease
2 MIN READ
0
Ricki Lewis’ Time Machine (3)
5 MIN READ
0
Creating nutrient-dependent life with enough genes to survive
3 MIN READ
0
Confusing effects and affects of visual input
2 MIN READ
0
Selective reporting of inferences: examples of pseudoscience
14 MIN READ
0
Energy-dependent purpose vs teleophobic telorexia
12 MIN READ
0
Virus-driven disorder prevention and health promotion
6 MIN READ
0
Stress-linked population-level history dependence
5 MIN READ
0
Do not miss the misrepresentations
2 MIN READ
0
Energy dependent RNA-mediated immunity (5)
4 MIN READ
0
Energy dependent RNA-mediated immunity (4)
6 MIN READ
0
Energy dependent RNA-mediated immunity (3)
8 MIN READ
0
Energy dependent RNA-mediated immunity (2)
10 MIN READ
0
Energy-dependent RNA-mediated immunity (1)
10 MIN READ
0
The toxic river of neo-Darwinian pseudoscience
3 MIN READ
0
Science vs semantics
4 MIN READ
0
From angstroms to ecosystems and entropy
2 MIN READ
0
Bacteria see the light and they adapt (2)
5 MIN READ
0
Soil bacteria, bulls, cows, microRNAs, and mammary glands (2)
3 MIN READ
0
Soil bacteria, bulls, cows, microRNAs, and mammary glands
3 MIN READ
0
Bringing RNA back to epigenetics (20 years later)
11 MIN READ
0
Effects on invertebrate GnRH and affects on primate behavior
6 MIN READ
0
Creating gravity, nucleic acids, receptors, and supercoiled DNA (2)
9 MIN READ
0
Nutrient-dependent RNA-mediated cause and effect
3 MIN READ
0
Creating gravity, nucleic acids, receptors, and supercoiled DNA
2 MIN READ
0
Bacteria see the light and they adapt
7 MIN READ
0
Models of scientific literacy
3 MIN READ
0
Organic Compounds and the Miracle of Smell and Taste
7 MIN READ
0
Neuroscience Virtual Event vs AAAS Symposium
3 MIN READ
0
Cancer: Evolution 2.0’s Blind Spot
13 MIN READ
0
Despicable fools?
4 MIN READ
0
Ricki Lewis’ Time Machine
5 MIN READ
0
Virus-perturbed alternative splicings
3 MIN READ
0
Hydrogen-atom transfer in DNA base pairs (5)
10 MIN READ
0
The radical pair mechanism of ecological speciation
3 MIN READ
0
Brain evolution?
< 1 MIN READ
0
Center stage RNA-mediated events (since 1996)
3 MIN READ
0
The unoffically uninvited
3 MIN READ
0
Blood test links atoms to ecosystems
2 MIN READ
0
A failed theory of cancer: two more decades of pseudoscience
5 MIN READ
0
Teleophobes vs teleophiles: a recent history
2 MIN READ
0
Ecological genomics: teleophobes respond (too late)
10 MIN READ
0
Genes, orchid odors, and pheromones from blonds
5 MIN READ
0
RNA-mediated theory killers (11) (12) (13) (14) (15)
7 MIN READ
0
Finding peace and π in the light of H bond energy (2)
8 MIN READ
0
MicroRNA-mediated RNA epigenetics
2 MIN READ
0
RNA methylation, RNA-directed DNA methylation, learning and memory
3 MIN READ
0
Finding peace and π in the light of H bond energy
5 MIN READ
0
Perry Marshall: too much information for atheist PZ Myers
3 MIN READ
0
Epigenetic (re)programming of behavior
4 MIN READ
0
Assumptions prove ignorance
5 MIN READ
0
Neo-Darwinian sink testing
2 MIN READ
0
NORAD: air defense and defense against genomic entropy
7 MIN READ
0
Life history transitions and RNA-mediated survial
2 MIN READ
0
Did Brain Atrophy Evolve?
2 MIN READ
0
Did Dobzhansky see the UV light of creation?
10 MIN READ
0
RNA-mediated theory killers (6) (7) (8) (9) (10)
5 MIN READ
0
Does metabolism link beneficial mutations to cancer?
10 MIN READ
0
Hydrogen-Atom Transfer in DNA Base Pairs (3)
3 MIN READ
0
Manufacturing fossil “evidence”
4 MIN READ
0
RNA-mediated theory killers (4)
9 MIN READ
0
RNA-mediated theory killers (3)
7 MIN READ
0
RNA-mediated regulatory mechanisms link microbes to humans (3)
5 MIN READ
0
Hydrogen-Atom Transfer in DNA Base Pairs (2)
< 1 MIN READ
0
Essential pseudoscientific concepts of atheism
3 MIN READ
0
RNA-mediated theory killers (2)
8 MIN READ
0
RNA-mediated theory killers
6 MIN READ
0
Natural cooperation and Evolution 2.0
6 MIN READ
0
A million dollar paradox?
2 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (4)
6 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (5)
4 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (3)
8 MIN READ
0
Teaching the biologically uninformed
3 MIN READ
0
MicroRNAs vs Red Queen hypothesis
4 MIN READ
0
Innovative Neurotechnologies Link Sunlight to Precision Medicine
4 MIN READ
0
Hydrogen-Atom Transfer in DNA Base Pairs
9 MIN READ
0
The Sherlock lab: Beneficial mutations
5 MIN READ
0
Neo-Darwinism vs the neocortex
4 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair
2 MIN READ
0
Life and death predicted by DNA methylation
3 MIN READ
0
Virally derived RNA molecules and cell types
2 MIN READ
0
Phenols: Laws of physics meet biology
2 MIN READ
0
Plasma created by sunlight and RNA–mediated epigenetic heredity
2 MIN READ
0
Positive feedback loops and epigenetic traps
2 MIN READ
0
Behavioral Immune System model
4 MIN READ
0
Stress-perturbed mitochondrial dysfunction
4 MIN READ
0
Understanding cell type differentiation
3 MIN READ
0
Let there be anti-entropic light (3)
6 MIN READ
0
Theorists can’t understand biology
6 MIN READ
0
Neuroplasticity
4 MIN READ
0
Sensationalizing no new mechanism
2 MIN READ
0
Cell type differentiation: atoms to ecosystems
2 MIN READ
0
Too complex for the Complex Biological Systems Alliance
4 MIN READ
0
More re-evolved functional structures?
2 MIN READ
0
Rediscovering quantum behavior
2 MIN READ
0
From dust to genomic entropy?
3 MIN READ
0
Virus, transposon and plasmid evolution
< 1 MIN READ
0
Conserved molecular mechanisms
< 1 MIN READ
0
Models are not theories (2)
2 MIN READ
0
Models are not theories (1)
2 MIN READ
0
MicroRNA-encoded behavior
7 MIN READ
0
Fossils vs cell types and the brain
3 MIN READ
0
Can veterans and other prisoners escape pseudoscience?
2 MIN READ
0
Cyclic cosmology and the stability of organized genomes
4 MIN READ
0
eQTLs and ecological adaptation
< 1 MIN READ
0
RNA central and RNA-mediated.com
6 MIN READ
0
Ecological speciation. Get it, theorists?
< 1 MIN READ
0
Designing, engineering, and protecting biodiversity
3 MIN READ
0
The virome, microbiome, replisome and supercoiled DNA
2 MIN READ
0
Skip the politics; embrace the facts
5 MIN READ
0
Controled Stem Cell Expansion
3 MIN READ
0
Neo-Darwinian logic is nonsense
3 MIN READ
0
FREE* SAMPLE: Histone modification
4 MIN READ
0
700 million years of evolution?
5 MIN READ
0
Biophysically constrained or unconstrained?
2 MIN READ
0
Mutated mitochondrial genes vs Supercoiled DNA
2 MIN READ
0
RNA-mediated retrotransposon-mediated biodiversity
3 MIN READ
0
Mystery machine vs model (2)
2 MIN READ
0
Mystery machine vs model
2 MIN READ
0
Mystery machine vs medical intelligence
2 MIN READ
0
The Current State of Neuroscience
3 MIN READ
0
Cancer: forward and reverse
2 MIN READ
0
Energy and evolution: another opinion?
2 MIN READ
0
Bird watchers and RNAs in cancers
2 MIN READ
0
Supercoiled DNA constrains virus-driven genomic entropy
2 MIN READ
0
Let there be anti-entropic light (2)
4 MIN READ
0
Foundamentals of theory
4 MIN READ
0
Microbes to humans 2015 Nobel Prize
2 MIN READ
0
Is mainstream science in “Science” pseudoscience?
5 MIN READ
0
Mechanisms of stress: from genes to cancer
9 MIN READ
0
Viruses come alive: Tree of life pseudoscience
6 MIN READ
0
Theorists have not seen the light (2)
3 MIN READ
0
Hijacked light energy and vertebrate pathology
4 MIN READ
0
Theorists have not seen the light
4 MIN READ
0
A 5-10K comparison of design principles to evolution
3 MIN READ
0
Alternative pre-mRNA splicing and ecological adaptation
7 MIN READ
0
Nucleic acids: Stability of DNA/RNA
2 MIN READ
0
Exosomes and the RNA-mediated future of medicine (3)
2 MIN READ
0
Exosomes and the RNA-mediated future of medicine (2)
< 1 MIN READ
0
Exosomes and the RNA-mediated future of medicine
5 MIN READ
0
Multi-omic analysis features (SNPs, miRNA)
3 MIN READ
0
Anti-entropic effects on the origin of life
< 1 MIN READ
0
Somatic hypermutation vs RNA-mediated events
2 MIN READ
0
From fertilization to RNA-mediated events and back
2 MIN READ
0
Phytochemical link from the sun to cell types
2 MIN READ
0
Metabolic competition and cancer
2 MIN READ
0
Natural selection: an anti-entropic force?
2 MIN READ
0
Genome sequencing, cadherins, and quantum consciousness
6 MIN READ
0
“New” quantum biology. Pirating the old
3 MIN READ
0
Creating genes and species
3 MIN READ
0
Cell types, SNVs, CNVs, and chromosomes
3 MIN READ
0
A “new” code enables ecological adaptation
4 MIN READ
0
Thermotolerance and Longevity
57 MIN READ
0
Is life the balance between quantum and classical physics?
3 MIN READ
0
Anti-entropic containment of energy: symbiosis 1.0
5 MIN READ
0
RNA-mediated X chromosome inactivation
3 MIN READ
0
The “great filter” is an epigenetic trap
4 MIN READ
0
Atomic-resolution of cell type signaling
4 MIN READ
0
Information and communication
2 MIN READ
0
Unraveling evolutionary pseudoscience
2 MIN READ
0
Eibi Nevo gets it wrong
3 MIN READ
0
Rs3827760 is Val370Ala and EDARV370A
3 MIN READ
0
From “Blood Music” to Evolution 2.0
5 MIN READ
0
Olfaction & the octopus and human genomes (2)
4 MIN READ
0
Olfaction & the octopus and human genomes
3 MIN READ
0
Protosuns, prebiotic molecules, proteins, and people
4 MIN READ
0
Mammalian-wide interspersed repeats (MIRs)
2 MIN READ
0
Ecological speciation vs revised evolutionary syntheses
6 MIN READ
0
Ecology replaces the extended evolutionary synthesis
4 MIN READ
0
The stability of organized genomes (4)
3 MIN READ
0
The stability of organized genomes (3)
3 MIN READ
0
The stability of organized genomes (2)
5 MIN READ
0
Epimutation.com: a domain of confusion
8 MIN READ
0
Light -induced nucleic acid-mediated gene duplication?
< 1 MIN READ
0
Is the best Chinese research from China?
3 MIN READ
0
The stability of organized genomes
5 MIN READ
0
Viruses, amino acids, and somatic cell types (3)
9 MIN READ
0
Viruses, amino acids, and somatic cell types (2)
5 MIN READ
0
Big Bang Cosmology vs Reality
< 1 MIN READ
0
RNA-mediated terms of virus-induced en-deer-ment
2 MIN READ
0
Chromosomal rearrangements and domestication
3 MIN READ
0
Domestication via a single amino acid substitution
2 MIN READ
0
Hematopoiesis and practopoiesis
4 MIN READ
0
RNA-mediated morphological AND behavioral phenotypes
2 MIN READ
0
Becoming biologically informed (3)
3 MIN READ
0
Easy editing: Reinventing our RNA world
3 MIN READ
0
Is photic-zone ribosomal diversity linked to all biodiversity?
2 MIN READ
0
Picornaviruses moving between primates (or not)
2 MIN READ
0
Riding the wrong direction
3 MIN READ
0
Decreased phenotypic variation: Faith in Facts
7 MIN READ
1
Faithfully repaired DNA
5 MIN READ
0
RNA-mediated gene duplication, fixation, and ecological adaptation
6 MIN READ
0
MicroRNA controlled growth and brain development
7 MIN READ
0
MicroRNA – controlled ecological adaptations
5 MIN READ
0
Celebrating independence from ridiculous theories
3 MIN READ
0
“New” epigenetic mechanism for lifelong learning?
3 MIN READ
0
The sum of our RNA-mediated parts
2 MIN READ
0
Protein folding and Google page rank
2 MIN READ
0
Iron, ferritin, thyroxine
2 MIN READ
0
“Evolution” of sex differences?
2 MIN READ
0
Nutrient stress-induced RNA-mediated pathology
< 1 MIN READ
0
Amino acid substitutions are not mutations
2 MIN READ
0
RNA-mediated events from A to Z
2 MIN READ
0
What I cannot create I eliminate from discussion
3 MIN READ
0
RNA-mediated development
2 MIN READ
0
Creating and maintaining the human virome
2 MIN READ
0
Healthy mutants
2 MIN READ
0
Uniquely epigenomic gene regulation
2 MIN READ
0
MicroRNAs and inappropriate functions
2 MIN READ
0
Rejecting pseudoscientific nonsense
6 MIN READ
1
Living the life that randomness created? (Sarcasm alert)
3 MIN READ
0
30 years of theoretical nonsense
3 MIN READ
0
microRNAs, glycosylation, and genomes
4 MIN READ
0
Unknown mechanisms and conclusions
2 MIN READ
0
Alternative splicings: epigenetics meets pharmacogenomics
4 MIN READ
0
Epigenetic regulation of aging by glycine and GnRH
5 MIN READ
0
Physicians who practice evolutionary medicine?
3 MIN READ
0
Pattern recognition: biogeochemical structure and function
5 MIN READ
0
Tweaking the story to fit the theory
5 MIN READ
0
Appetite for ingesting theories (raw)
< 1 MIN READ
0
I forgot. How do mutations cause evolution?
4 MIN READ
0
One amino acid substitution, genes, and brain activity
3 MIN READ
0
Batch effect vs epigenetic effects
3 MIN READ
0
Gene expression, immortality, and cancer
6 MIN READ
0
Missing a fact: microRNAs are genomic biomarkers
4 MIN READ
1
Bee-birthed epigenetics and primate cell types
5 MIN READ
0
A lighting requirement for life
11 MIN READ
3
Scientists lose. A sci-fi author gains credibility
2 MIN READ
0
Vitamin B3 and DNA repair
4 MIN READ
0
Bees and primates automagically evolve
3 MIN READ
0
Ignoring systems complexity (it’s too complicated)
3 MIN READ
0
Five years of Ferguson
2 MIN READ
0
Computing via phosphorylation and fixation
3 MIN READ
0
Virus-driven cancer treatment and prevention
2 MIN READ
0
The microbiome, pharmacogenetics, and privacy
< 1 MIN READ
0
Retinoic acid + one receptor regulate the genome
3 MIN READ
0
Epigenetics: microRNAs effect an integrative pathway
4 MIN READ
0
Protein isoforms do not evolve
3 MIN READ
0
Tissue type variation and expression of genes
< 1 MIN READ
0
From gut bacteria to breast milk and back
5 MIN READ
0
Chance mutations — not natural selection
5 MIN READ
0
Viruses in gut microbes
4 MIN READ
0
Physics, chemistry, light, and life
2 MIN READ
0
Finding odor and taste receptors everywhere
6 MIN READ
0
Linking the origin of birds to dinosaurs
< 1 MIN READ
0
pH, water, amino acids and protein folding
4 MIN READ
0
An epigenetic mark links algae, worms, and flies
2 MIN READ
0
Effect and affect of a single base-pair change
4 MIN READ
0
Tet3 regulation of nutrient-dependent cell type differentiation
4 MIN READ
0
Thermodynamics and protein folding landscapes
2 MIN READ
0
RNA-mediated silencing of a chromosome
3 MIN READ
0
Viruses, proteins, and gut metagenomes do not evolve
< 1 MIN READ
0
Pathology constrains X-linked evolution
2 MIN READ
0
Feedback loops link insects to human brains
2 MIN READ
0
Viruses and cell type differentiation
3 MIN READ
0
RNA-mediated cell types and precision medicine
5 MIN READ
0
DNA Methylation and organized genomes (2)
10 MIN READ
0
DNA Methylation and organized genomes
7 MIN READ
0
Misunderstanding cancer
7 MIN READ
0
Amino acid-dependent cell type differentiation
8 MIN READ
0
Nutrient-dependent RNA interference (2)
4 MIN READ
0
The Darwin Code by Greg Bear
13 MIN READ
0
Nutrient-dependent RNA interference
4 MIN READ
0
Mutisensory integration: watching the paradigm shift
12 MIN READ
0
Origin of life and cancer (1,2,3)
2 MIN READ
0
A genetic variant refutes neo-Darwinism
6 MIN READ
0
MicroRNAs and invasive phenotypes
< 1 MIN READ
0
Silencing genes and serious scientists
3 MIN READ
0
The miRNA/mRNA balance: a suboptimal strategy?
2 MIN READ
0
Nutrient-dependent microRNAs control cell types
6 MIN READ
0
Deeply ingrained thoughts
< 1 MIN READ
0
Graphic misrepresentations of ecological adaptation
2 MIN READ
0
Too many targets for theories
3 MIN READ
0
Methylation maintains cell type differences (2)
2 MIN READ
0
Methylation maintains cell type differences
3 MIN READ
0
Creating nothing but a theory (3)
4 MIN READ
3
Creating nothing but a theory (2)
4 MIN READ
0
Creating nothing but a theory
4 MIN READ
0
Viruses and ecologically adapted animals
2 MIN READ
0
2 genes in 2 species (too expensive and too insignificant)
11 MIN READ
0
The quantum / classical RNA-mediated ‘tipping point’
3 MIN READ
0
Epigenetic effects of soil bacteria on plants
< 1 MIN READ
0
Epigenetic switch links MicroRNAs to RNA-protein interactions
4 MIN READ
0
Quantum correlations/pseudoscience
3 MIN READ
0
Anti-entropic solar energy
5 MIN READ
0
Mimicking claims and ignoring facts
4 MIN READ
0
Correctly modeling life on this planet
3 MIN READ
0
Correctly modeling ecological adaptation
4 MIN READ
0
Behavior (4): All responses are RNA-mediated in birds
4 MIN READ
0
Questions about life’s diversity
21 MIN READ
0
UV-light mutations and gene loss (not gain)
5 MIN READ
0
Virus-driven origin of life
2 MIN READ
0
Luis P. Villarreal tells it like it is
3 MIN READ
0
RNA-directed gene choice
5 MIN READ
0
Walk towards the light
< 1 MIN READ
0
Two types of microRNA are not double agents
2 MIN READ
0
Epigenetics Skeptism
5 MIN READ
0
Assembling yourself: Molecular self / other recognition
4 MIN READ
0
What about birds?
5 MIN READ
0
Virus-driven cell type differentiation
2 MIN READ
0
RNA directed DNA methylation and cell types
4 MIN READ
0
Implicating microRNAs in cancer
2 MIN READ
0
Rejecting what is known about viral microRNAs and nutrient-dependent microRNAs
2 MIN READ
0
Reverse phosphorylation
7 MIN READ
0
RNA-mediated repurposing in microbes and adaptations in primate brains
2 MIN READ
0
RNA-mediated “repurposing” is nutrient-dependent and pheromone-controlled
3 MIN READ
0
RNA-mediated "repurposing" is nutrient-dependent and pheromone-controlled
3 MIN READ
0
From 3-D to epigenetically-effected 4-D genome make-up
5 MIN READ
0
Let there be anti-entropic light (1)
11 MIN READ
0
An epigenetic trap (the prequel)
5 MIN READ
0
Imagining that data historically supports evolutionary theory
7 MIN READ
0
Atheism: Arrogant, useless, and divisive ignorance
7 MIN READ
0
The anti-entropic force of "Nature"
2 MIN READ
0
Nutritional epigenetics, exercise, and immune system integrity
4 MIN READ
0
What if Darwin was not still dead?
2 MIN READ
0
Military combat training to fight disease (2)
3 MIN READ
0
Military combat training to fight disease
3 MIN READ
0
Theoretical physics and molecular biology
5 MIN READ
0
Atoms to ecosystems is not almost a molecular ecology
3 MIN READ
0
Epigenetic effects of viruses on cellular homeostasis (2)
2 MIN READ
0
RNA-mediated epigenetic modification via DNA-methylation
4 MIN READ
0
Quantum physics, quantum biology, and quantum consciousness
4 MIN READ
0
How fast can evolutionary theory be changed?
5 MIN READ
0
Biological energy and a microbiome model of a light-driven time machine
3 MIN READ
0
The biologically-based origin of the mammalian placenta (2)
6 MIN READ
0
Quantum Superpositions: let there be light
4 MIN READ
0
Are viruses microRNAs? (2)
5 MIN READ
0
Are viruses microRNAs?
3 MIN READ
0
Sneaking up from behind (2)
3 MIN READ
0
Sneaking up from behind
4 MIN READ
0
Quantum entanglement, mass, and biomass
4 MIN READ
0
Physicists: Desperate Acts
16 MIN READ
0
An epigenetic trap (the sequel)
10 MIN READ
0
Mute points: most are afraid to mention them
6 MIN READ
0
All of “like kind” (Part 2)
2 MIN READ
0
All of "like kind" in the (bigger) family
6 MIN READ
1
Environment epigenetically shapes the immune system
3 MIN READ
0
Beneficial microbes kill beneficial mutations
4 MIN READ
0
Constrained evolution is ecological adaptation
5 MIN READ
0
A single amino acid substitution differentiates cell types of E. coli
3 MIN READ
0
Unconstrained evolutionary innovability
4 MIN READ
0
RNA-protein interactions reveal biophysical to ecological landscapes
2 MIN READ
0
Mutagenesis: Replacing facts with theories
5 MIN READ
0
ISHE's human ethology group
2 MIN READ
0
Amino acid homeostasis for a Happy New Year!
6 MIN READ
0
Understanding cell type differentiation
3 MIN READ
0
From Hydra to humans vs a Lakatosian research program
4 MIN READ
0
Unified nutritional and molecular mechanisms
9 MIN READ
0
Removing natural selection; reshaping the horse; adjusting evolutionary theory
4 MIN READ
0
Communication, not mutations
2 MIN READ
0
Models by evolutionary biologists are not models
2 MIN READ
0
The future of physics predicts no future for evolutionary theory
3 MIN READ
0
Model organisms: the birds and the bees
3 MIN READ
0
Chemical ecology and RNA-mediated control of DNA loops
< 1 MIN READ
0
Atoms to ecosystems: Evolutionary theory vs the coelacanth
6 MIN READ
0
Jumping back: Science or Pseudoscience? (2)
2 MIN READ
0
Jumping back: Science or Pseudoscience?
6 MIN READ
0
Single-cell level assay of protein biosynthesis and degradation
2 MIN READ
0
Glycine and GnRH: Am I being pedantic?
4 MIN READ
0
Extensive molecular evidence vs ridiculous theories
2 MIN READ
0
Dual genomes: exposing the evolution industry
5 MIN READ
0
One test of bioenergetic health?
2 MIN READ
0
Meaningful dialogue, anonymous fools and idiot minions
4 MIN READ
0
Epigenetic pharmacology and RNA-mediated transciptional landscapes
3 MIN READ
0
RNA-mediated events and "The Theory of Everything"
4 MIN READ
0
Sackler Colloquium: Effects or AFFECTS on Behavior
2 MIN READ
0
Thermodynamic constraints and ecological adaptations sans evolution
6 MIN READ
0
Eliminating correlations from evolutionary ecology
6 MIN READ
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RNA-mediated species specificity
2 MIN READ
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Are mutations beneficial?
4 MIN READ
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The key to science: experimental evidence
5 MIN READ
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Ecological adaptations reported as evolution in insects and mammals
4 MIN READ
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There’s a model for that!
5 MIN READ
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Biologists puzzled by evolved RNAs and decaying DNA
6 MIN READ
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SNPs and millions of small variations in the human genome
3 MIN READ
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More than a bag of chemicals?
2 MIN READ
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Achiral GnRH: no prophesy, just prediction
9 MIN READ
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Nothing new under the sun, except pseudoscientific nonsense
6 MIN READ
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Making sense of quotes scattered across disciplines
2 MIN READ
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Intelligent viruses and cancers?
10 MIN READ
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Complex behaviors of cell types in cancer
6 MIN READ
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De novo DNA methylation?
3 MIN READ
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RNA eclipses the importance of DNA to cell type differentiation
4 MIN READ
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We need pattern recognition, not proclamations
3 MIN READ
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We need pattern recognition, not a prologue
6 MIN READ
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Pharmacogenomics
3 MIN READ
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Sexual differentiation of cell types in plants
2 MIN READ
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A model of MHC 'evolution'
2 MIN READ
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From deep time into real time: What evolutionary processes?
10 MIN READ
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In theory, or supported by experimental evidence?
5 MIN READ
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It’s cell type differention, not cell fate determination (2)
3 MIN READ
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Are evolutionary theorists 'nob ends'?
5 MIN READ
2
ALPHA GENOMIX
7 MIN READ
2
No excuses: Creation and the meaning of organismal complexity
7 MIN READ
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Nutrient-dependent gene duplication in plants (but not animals?)
4 MIN READ
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Evolutionary theorists justify fear of the Ebola viruses
2 MIN READ
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Evolutionary theorists and evolutionary theists live under rocks
< 1 MIN READ
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No understanding of biodiversity
2 MIN READ
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Understanding physical forces of ecological variation and adaptation
< 1 MIN READ
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Eliminating evolutionary theory
3 MIN READ
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Behavioral ecology: please continue to believe in our fantasies
3 MIN READ
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2014 and 2004 Nobel Prize in Medicine
3 MIN READ
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How much good can be attributed to social science theories?
< 1 MIN READ
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RNA-mediated genetic engineering (Part 3)
< 1 MIN READ
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RNA-mediated genetic engineering (Part 2)
3 MIN READ
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RNA-mediated genetic engineering
2 MIN READ
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RNA-mediated events are not a matter of faith
2 MIN READ
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Color vision refutes the evolutionary dogma of gene duplication
4 MIN READ
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Unassailable evidence vs assumptions
4 MIN READ
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Forces of "Nature" limit dissemination of information
4 MIN READ
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Genomic surveillance ends our world of RNA-mediated ecological adaptations
2 MIN READ
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Systems biology and memory disorders
3 MIN READ
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RNA-mediated cell type differentiation and behavior
3 MIN READ
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Different physical locations and different molecular mechanisms of health and disease
2 MIN READ
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Metabolism, fixation, health or neurodegerative disorder
2 MIN READ
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Physics, Chemistry, and Molecular biology (PCMb)
2 MIN READ
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Physics denied; pseudoscientific nonsense accepted
2 MIN READ
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Ecological variation and niche construction: 1, 2, 3
6 MIN READ
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Epigenetically-effected metabolic shifts and ecological adaptations
3 MIN READ
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Evolving DNA before RNA
4 MIN READ
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Stop evolutionary theorists. Kill cancers
3 MIN READ
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Did our adapted mind evolve? (Revisited)
2 MIN READ
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De novo gene Creation sans evolution of genes via mutations
4 MIN READ
0
Did our adapted mind evolve?
6 MIN READ
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RNA-directed DNA methylation and RNA-mediated events
5 MIN READ
1
Miracles are not miracles to evolutionary theorists
2 MIN READ
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Mathematical model: microRNA and epigenetic regulation
2 MIN READ
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Seemingly futile cycles are not thermodynamically futile
3 MIN READ
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Do bacterial proteins evolve?
3 MIN READ
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“Kardashians” in science
< 1 MIN READ
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Probable changes in connectivity
2 MIN READ
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New technique used in report of atomic-level ecological adaptations
3 MIN READ
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Can epigenetic inheritance occur without concurrent changes in morphology AND behavior?
3 MIN READ
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Memory of repression and memory of behavior (2)
< 1 MIN READ
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Memory of repression and memory of behavior
2 MIN READ
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Quantum physics meets Evolutionary Psychology News
2 MIN READ
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Nutrient-dependent pheromone-controlled exercise-induced physiques
< 1 MIN READ
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Watching and waiting for more retractions
2 MIN READ
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RNA-mediated ecological adaptations of teeth
4 MIN READ
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A molecular visualizer of worthwhile molecular biology
2 MIN READ
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RNA-mediated species diversification from microbes to primates
3 MIN READ
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RNA-mediated events found everywhere
2 MIN READ
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Reseachers think copy number variation is genetically determined
< 1 MIN READ
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Some neuroscientists think a mutation led to human language development
< 1 MIN READ
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Genotype, observed phenotype, and distinctly disordered behaviors
3 MIN READ
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Is the problem an internet echo or Feierman's ethics?
2 MIN READ
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Behavior (3): All responses are RNA-mediated in bees
3 MIN READ
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RNA-mediated ecological adaptation is not evolution
2 MIN READ
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Exploding genomes and chromosomal rearrangements via RNA-mediated events
2 MIN READ
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Behavior (2): All responses are RNA-mediated not genetically-determined
4 MIN READ
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Behavior: The first response is RNA-mediated not genetically-determined
3 MIN READ
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Mechanisms that are not understood increase clarity
4 MIN READ
2
Pattern recognition and conserved receptors (TAARs)
5 MIN READ
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Nutrient-dependent erythropoiesis and anemia
6 MIN READ
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Evolutionary heritage or ecological adaptation? Racism versus reality
4 MIN READ
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A relatively young branch of science called epigenetics
4 MIN READ
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Insect homology and diversity attributed to mutations
2 MIN READ
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Biophysically constrained beginnings of RNA and DNA
4 MIN READ
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Baby talk: More misrepresentations of ecological adaptations
2 MIN READ
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Comparing divergent model organisms
2 MIN READ
1
A microRNA-mediated mechanism that is epigenetically inherited
2 MIN READ
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Epimutations: Attacking pseudoscientific dogmas
4 MIN READ
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Order and disorder: Ecological adaptations not mutations
6 MIN READ
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microRNAs differentiate neuronal cell types
3 MIN READ
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microRNAs and species relationships
3 MIN READ
0
Drunks and Monkeys: Pseudoscientific nonsense
2 MIN READ
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The quantum biology of consciousness
3 MIN READ
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Behavior is receptor-mediated
10 MIN READ
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Genes and Race: Human History?
2 MIN READ
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Soft atheism: a case for Creation
< 1 MIN READ
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Nutrition, pheromones and cancer (2)
2 MIN READ
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Ecologically linked adapted ants and brains
2 MIN READ
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MiRNAs methylation and ecological adaptation sans mutations
2 MIN READ
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Not focused and self-aggrandizing
2 MIN READ
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Nutrient-dependent cooperation vs cannibalism (video)
2 MIN READ
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Cell-type differentiation
2 MIN READ
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Another powerful refutation of mutation-initiated natural selection
4 MIN READ
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The new light of chromosomal rearrangements
3 MIN READ
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Darwinian theories vs Darwin's facts
2 MIN READ
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Chromosomal rearrangements and ecological adaptations
4 MIN READ
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The wrong picture of our evolution
4 MIN READ
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96 fixed amino acid substitutions, not 96 genes
6 MIN READ
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Jay R. Feierman
3 MIN READ
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Don't tell the Creationists
2 MIN READ
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Targeting a cancer gene
2 MIN READ
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Alternative splicings (very technical)
2 MIN READ
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Pulses of olfactory/pheromonal input
2 MIN READ
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Social experiences epigenetically effect gene networks
2 MIN READ
0
Pheromone-controlled thermodynamics and cancer
2 MIN READ
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Seeds of life: astrobiological theory and mutations theory
3 MIN READ
0
Your comment is awaiting moderation
2 MIN READ
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Nutrient-dependent pheromone-controlled stickleback evolution
2 MIN READ
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Functional coding variants are not mutations
2 MIN READ
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Mirror neurons and microRNA: theory vs biological facts
4 MIN READ
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Understanding the role of mutations and evolution
4 MIN READ
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Evolution: innovations may have non-adaptive origins (sans mutations)
2 MIN READ
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Pheromones and cancer
4 MIN READ
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Are pheromones responsible for human body odour assessment?
2 MIN READ
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Epigenetic effects underlie sexual preferences IV
< 1 MIN READ
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A key mutational event? That’s not very likely.
3 MIN READ
0
Disorders of development: altered microRNA / messenger RNA balance
< 1 MIN READ
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Evolution at work sans random mutations (Part 2)
< 1 MIN READ
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Evolution at work sans random mutations
2 MIN READ
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Sex differences in Alzheimer's and everything else
2 MIN READ
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CB Nemeroff: Off Restriction
< 1 MIN READ
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A thought experiment
3 MIN READ
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More than speculation: adaptive evolution in species from microbes to man
2 MIN READ
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Honeybees, food odors, and perfume
< 1 MIN READ
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Nice comments JVK. Linking molecular vibration sensing to de novo creation of olfactory receptor genes would be a challenge. I suppose it should start with the most primitive organisms we know of that have the complexity to direct the olfactory receptor palette in their own body and perhaps in that of their immediate progeny
Thanks, John. I think that Luca Turin was very close to establishing a species-wide epigenetic link to cell type differentiation via molecular vibrations and experience-dependent odor-induced de novo creation of olfactory receptor genes in species from microbes to man. Unfortunately, I don’t think he will pursue this due to the systems complexity required to link quantum physics to the chemistry of protein folding and the conserved molecular mechanisms of biodiversity. Why bother when your colleagues still think only in terms of mutations, natural selection, and the evolution of biodiversity? Teaching them about physics, chemistry, and molecular biology is akin to teaching pigs to sing.
[…] RNA-mediated events: chromosomal rearrangements and genomic rearrangements, I […]