RNA-mediated silencing (3)
(click to enlarge)
Robert H. Singer, co-authored: Single-molecule imaging of microRNA-mediated gene silencing in cells 3/17/22
Simultaneous visualization of single mRNAs, translation, and miRNA-binding revealed that miRNAs preferentially bind to translated mRNAs rather than untranslated mRNAs.
Trust in God, but verify the fact that Singer’s publication history links God’s Creation of anti-entropic virucidal energy to biophysically constrained microRNA-mediated protein folding chemistry and healthy longevity across kingdoms via light-activated carbon fixation in cyanobacteria, and pheromone-regulated genetic processes of preferential binding and reproduction in species from yeasts to humans.
See: Photon-Counting CMOS Sensors Extend Frontiers in Scientific Imaging
See also: MicroRNAs organize intrinsic variation into stem cell states 3/5/20
…naturally arising cell-to-cell variation, sometimes described as stochastic fluctuation, is in fact coherently organized biology.
Link quantum coherence to coherently organized biology via God’s Creation of species-specific cell membranes in this STEM toy for ages 14+: Cellulose
Link quantum biology to effective treatment of cancer via food energy-dependent microRNA abundance compared to virus-driven mutations.
See also: Quantifying the contribution of transcription factor activity, mutations and microRNAs to CD274 expression in cancer patients 3/14/22
…CD274 expression is largely explained by TF activity, and the remaining unexplained cases can largely be explained by mutations or low miRNA abundance.
Low miRNA abundance is caused by the virus-driven degradation of mRNA. Viruses steal the energy that links what organisms eat to microRNA-mediated DNA repair.
Link that fact to effective treatment of cancer via the patent for Methods and compositions for identifying a peptide having an intermolecular interaction with a target of interest 12/25/18
A system of a recombinant bacteriophage library and a target of interest complex, wherein the recombinant bacteriophage peptide library includes a plurality of peptides expressed on the surface of recombinant bacteriophages…
Link bacteriophages to all virus-driven pathology via the degradation of mRNA. Link light-activated microRNA biogenesis from carbon fixation in cyanobacteria to microRNA-mediated protein folding chemistry and healthy longevity via Cellulose: A Plant Cell Biology Game
See examples of COVID-19 linked human idiocy for comparison: A time to reflect 3/10/22
…the virus sequence was swiftly solved, and the spike protein structure emerged.
Spike protein structure did not automagically emerge at the time the virus sequence was solved. Look back at what happened when greedy profiteers corrupted the entirety of the medical-industrial complex via their failure to start with God’s Creation of sunlight and humidity.
On 4/23/20, former President Trump linked it to the end of COVID-19 via what was known to all intelligent serious scientists about physics, chemistry, and molecular interactions across kingdoms in the context of Thomas Hunt Morgan’s 1910 claims about food energy-dependent pheromone- regulated ecological adaptations in Drosophila.
See for review: Genotype (for ages 14+)
See for comparison: Direct observation of adaptive tracking on ecological time scales in Drosophila 3/18/22
Adaptation is a foundational process in evolutionary biology that is central to human health and the conservation of biodiversity. Adaptive tracking, defined as continuous adaptation in response to rapid environmental change, is a potentially critical mechanism by which populations persist in changing environments.
From one week to the next, Science Magazine has pushed the limits of obfuscation to change the definition of evolutionary biology to ecological adaptation.
See for comparison: Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems 4/18/18
No one can be forced to apologize for their lack of knowledge, but some stupid theorists could be expected to apologize for their arrogance and ignorance in the context of what has been known for more than 110 years about energy-dependent biophysically constrained microRNA-mediated species-specific cell type differentiation and Genotypes.
How many theorists failed to link quantum coherence from coherently organized biology to quantum souls via microRNA-mediated stem cell creation? It is the obvious link to prevention of all virus-driven pathology via observable differences in the growth of Angel Trumpets and successful ecological adaptations in daffodils. Former President Trump announced that fact on 4/23/20 in the context of how sunlight and humidity weaken Covid-19.
Angel Trumpets are extinct in the wild. Daffodils are extremely well adapted. Other organisms and people who are not ecologically adapted suffer unnecessarily and die prematurely from the virus-driven degradation of mRNA.
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Hypothesis free pseudoscience vs facts (4)
5 MIN READ
0
Chromatin: The structure of DNA (2)
8 MIN READ
0
Chromatin: The structure of DNA (3)
4 MIN READ
0
Chromatin: The structure of DNA
6 MIN READ
0
Consciousness is simply food rearranged
2 MIN READ
0
DNA repair via junk DNA (2)
5 MIN READ
0
Light energy-dependent active motifs
6 MIN READ
0
Light energy-induced base pair changes (2)
4 MIN READ
0
Light energy-induced base pair changes (1)
6 MIN READ
0
Displays of ecological adaptation (2)
3 MIN READ
0
Unconstrained mutations, Zika virus, Kallmann’s syndrome
4 MIN READ
0
How did the innate immune system evolve?
4 MIN READ
0
The Aquatic Ape: New evidence?
4 MIN READ
0
Plant microRNAs slow virus-driven aging
3 MIN READ
0
Increased soil pH and nutrient availability
4 MIN READ
0
Energy-dependent cellular communication
3 MIN READ
0
Antithetical conclusions (5)
4 MIN READ
0
Anthetical conclusions (2)
5 MIN READ
0
RNAi: From magic bullet to billion dollar baby
4 MIN READ
0
Co-evolution and co-speciation replace neo-Darwinian nonsense
4 MIN READ
0
Energy-dependent natural fluorescence and bioluminescence
2 MIN READ
0
Pseudoscientists ignore what serious scientists prove
6 MIN READ
0
GC-rich neo-Darwinian train wreck
5 MIN READ
0
Food supplement or licensed immunostimulant?
6 MIN READ
0
Q and A: Energy-dependent cell type differentiation
10 MIN READ
0
Biophotonics, glycobiology, quantized biodiversity (2)
19 MIN READ
0
The tipping point? 50,000 publications (5)
3 MIN READ
0
Light ‘drives’ adaptation; nothing ‘drives’ evolution
6 MIN READ
0
Did “Nature” kill Steve Jobs?
3 MIN READ
0
RNA methylation, learning, memory and behavior,
< 1 MIN READ
0
Amino acids and virus penetration
3 MIN READ
0
RNA methylation, behavior, and disease
6 MIN READ
0
Energy-dependent RNA methylation (10)
4 MIN READ
0
Energy-dependent RNA methylation (7)
7 MIN READ
0
Energy-dependent RNA methylation (1)
6 MIN READ
0
Secular humanism and ecoterrorism
4 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (4)
5 MIN READ
0
RNA-mediated physics, chemistry, and molecular epigenetics (3)
5 MIN READ
0
Wasted Templeton Funding (4)
3 MIN READ
0
Molecular Diagnostics: What is unprotected life? (5)
5 MIN READ
0
Confusing effects and affects of visual input
2 MIN READ
0
Selective reporting of inferences: examples of pseudoscience
14 MIN READ
0
Ignore the evidence: Rachel Feltman
5 MIN READ
0
Energy-dependent purpose vs teleophobic telorexia
12 MIN READ
0
Virus-driven disorder prevention and health promotion
6 MIN READ
0
Stress-linked population-level history dependence
5 MIN READ
0
Energy dependent RNA-mediated immunity (4)
6 MIN READ
0
Energy-dependent RNA-mediated immunity (1)
10 MIN READ
0
Hydrogen-atom transfer in DNA base pairs (7)
5 MIN READ
0
Bacteria see the light and they adapt
7 MIN READ
0
Cancer: Evolution 2.0’s Blind Spot
13 MIN READ
0
Blood test links atoms to ecosystems
2 MIN READ
0
A failed theory of cancer: two more decades of pseudoscience
5 MIN READ
0
Ecological genomics: teleophobes respond (too late)
10 MIN READ
0
Amino acid substitutions, stress, and human behavior
3 MIN READ
0
Finding peace and π in the light of H bond energy
5 MIN READ
0
Neo-Darwinian sink testing
2 MIN READ
0
NORAD: air defense and defense against genomic entropy
7 MIN READ
0
RNA-mediated theory killers (4)
9 MIN READ
0
RNA-mediated regulatory mechanisms link microbes to humans (3)
5 MIN READ
0
Natural cooperation and Evolution 2.0
6 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (5)
4 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair (3)
8 MIN READ
0
Teaching the biologically uninformed
3 MIN READ
0
Neo-Darwinism vs the neocortex
4 MIN READ
0
A two-faced protein enables RNA-mediated DNA repair
2 MIN READ
0
Nutrient-dependent trophic analogs
3 MIN READ
0
Virally derived RNA molecules and cell types
2 MIN READ
0
Positive feedback loops and epigenetic traps
2 MIN READ
0
Theorists can’t understand biology
6 MIN READ
0
More re-evolved functional structures?
2 MIN READ
0
Conserved molecular mechanisms
< 1 MIN READ
0
Models are not theories (2)
2 MIN READ
0
RNA central and RNA-mediated.com
6 MIN READ
0
Skip the politics; embrace the facts
5 MIN READ
0
Preventing genomic entropy
4 MIN READ
0
Cancer: forward and reverse
2 MIN READ
0
Supercoiled DNA constrains virus-driven genomic entropy
2 MIN READ
0
Let there be anti-entropic light (2)
4 MIN READ
0
Mechanisms of stress: from genes to cancer
9 MIN READ
0
Gene creation (revisited)
2 MIN READ
0
Theorists have not seen the light
4 MIN READ
0
A 5-10K comparison of design principles to evolution
3 MIN READ
0
Alternative pre-mRNA splicing and ecological adaptation
7 MIN READ
0
Genome sequencing, cadherins, and quantum consciousness
6 MIN READ
0
“New” quantum biology. Pirating the old
3 MIN READ
0
Cell types, SNVs, CNVs, and chromosomes
3 MIN READ
0
Anti-entropic containment of energy: symbiosis 1.0
5 MIN READ
0
The “great filter” is an epigenetic trap
4 MIN READ
0
Information and communication
2 MIN READ
0
Rs3827760 is Val370Ala and EDARV370A
3 MIN READ
0
From “Blood Music” to Evolution 2.0
5 MIN READ
0
The stability of organized genomes (3)
3 MIN READ
0
Viruses, amino acids, and somatic cell types (3)
9 MIN READ
0
Viruses, amino acids, and somatic cell types (2)
5 MIN READ
0
Hematopoiesis and practopoiesis
4 MIN READ
0
RNA-mediated morphological AND behavioral phenotypes
2 MIN READ
0
Becoming biologically informed (3)
3 MIN READ
0
Easy editing: Reinventing our RNA world
3 MIN READ
0
Riding the wrong direction
3 MIN READ
0
RNA-mediated gene duplication, fixation, and ecological adaptation
6 MIN READ
0
MicroRNA – controlled ecological adaptations
5 MIN READ
0
“New” epigenetic mechanism for lifelong learning?
3 MIN READ
0
Iron, ferritin, thyroxine
2 MIN READ
0
Amino acid substitutions are not mutations
2 MIN READ
0
What I cannot create I eliminate from discussion
3 MIN READ
0
RNA-mediated development
2 MIN READ
0
microRNAs, glycosylation, and genomes
4 MIN READ
0
Alternative splicings: epigenetics meets pharmacogenomics
4 MIN READ
0
Epigenetic regulation of aging by glycine and GnRH
5 MIN READ
0
Pattern recognition: biogeochemical structure and function
5 MIN READ
0
Informing the biologically uninformed
< 1 MIN READ
0
I forgot. How do mutations cause evolution?
4 MIN READ
0
Batch effect vs epigenetic effects
3 MIN READ
0
Gene expression, immortality, and cancer
6 MIN READ
0
Missing a fact: microRNAs are genomic biomarkers
4 MIN READ
1
Vitamin B3 and DNA repair
4 MIN READ
0
Ignoring systems complexity (it’s too complicated)
3 MIN READ
0
Five years of Ferguson
2 MIN READ
0
Computing via phosphorylation and fixation
3 MIN READ
0
Virus-driven cancer treatment and prevention
2 MIN READ
0
A special issue on nutritional epigenetics
5 MIN READ
0
Retinoic acid + one receptor regulate the genome
3 MIN READ
0
Epigenetics: microRNAs effect an integrative pathway
4 MIN READ
0
Protein isoforms do not evolve
3 MIN READ
0
From gut bacteria to breast milk and back
5 MIN READ
0
MicroRNAs and the exposome
5 MIN READ
0
Thermodynamics and protein folding landscapes
2 MIN READ
0
Feedback loops link insects to human brains
2 MIN READ
0
Misunderstanding cancer
7 MIN READ
0
The Darwin Code by Greg Bear
13 MIN READ
0
Mutisensory integration: watching the paradigm shift
12 MIN READ
0
The miRNA/mRNA balance: a suboptimal strategy?
2 MIN READ
0
Nutrient-dependent microRNAs control cell types
6 MIN READ
0
Too many targets for theories
3 MIN READ
0
Methylation maintains cell type differences
3 MIN READ
0
Creating nothing but a theory
4 MIN READ
0
Epigenetic switch links MicroRNAs to RNA-protein interactions
4 MIN READ
0
Correctly modeling life on this planet
3 MIN READ
0
Questions about life’s diversity
21 MIN READ
0
Luis P. Villarreal tells it like it is
3 MIN READ
0
RNA-directed gene choice
5 MIN READ
0
What about birds?
5 MIN READ
0
Implicating microRNAs in cancer
2 MIN READ
0
RNA-mediated “repurposing” is nutrient-dependent and pheromone-controlled
3 MIN READ
0
RNA-mediated "repurposing" is nutrient-dependent and pheromone-controlled
3 MIN READ
0
An epigenetic trap (the prequel)
5 MIN READ
0
Nutritional epigenetics, exercise, and immune system integrity
4 MIN READ
0
Quantum physics, quantum biology, and quantum consciousness
4 MIN READ
0
How fast can evolutionary theory be changed?
5 MIN READ
0
Are viruses microRNAs? (2)
5 MIN READ
0
Sneaking up from behind (2)
3 MIN READ
0
Physicists: Desperate Acts
16 MIN READ
0
Constrained evolution is ecological adaptation
5 MIN READ
0
A single amino acid substitution differentiates cell types of E. coli
3 MIN READ
0
Understanding cell type differentiation
3 MIN READ
0
Models by evolutionary biologists are not models
2 MIN READ
0
Glycine and GnRH: Am I being pedantic?
4 MIN READ
0
Meaningful dialogue, anonymous fools and idiot minions
4 MIN READ
0
RNA-mediated species specificity
2 MIN READ
0
Ecological adaptations reported as evolution in insects and mammals
4 MIN READ
0
Nothing new under the sun, except pseudoscientific nonsense
6 MIN READ
0
Complex behaviors of cell types in cancer
6 MIN READ
0
RNA eclipses the importance of DNA to cell type differentiation
4 MIN READ
0
We need pattern recognition, not proclamations
3 MIN READ
0
We need pattern recognition, not a prologue
6 MIN READ
0
Are evolutionary theorists 'nob ends'?
5 MIN READ
2
ALPHA GENOMIX
7 MIN READ
2
No excuses: Creation and the meaning of organismal complexity
7 MIN READ
0
Nutrient-dependent gene duplication in plants (but not animals?)
4 MIN READ
0
Evolutionary theorists justify fear of the Ebola viruses
2 MIN READ
0
Evolutionary theorists and evolutionary theists live under rocks
< 1 MIN READ
0
RNA-mediated events: chromosomal rearrangements and genomic rearrangements
2 MIN READ
2
RNA-mediated genetic engineering (Part 3)
< 1 MIN READ
0
RNA-mediated events are not a matter of faith
2 MIN READ
0
Genomic surveillance ends our world of RNA-mediated ecological adaptations
2 MIN READ
0
Metabolism, fixation, health or neurodegerative disorder
2 MIN READ
0
Physics, Chemistry, and Molecular biology (PCMb)
2 MIN READ
0
Physics denied; pseudoscientific nonsense accepted
2 MIN READ
0
Evolving DNA before RNA
4 MIN READ
0
Stop evolutionary theorists. Kill cancers
3 MIN READ
0
RNA-directed DNA methylation and RNA-mediated events
5 MIN READ
1
Mathematical model: microRNA and epigenetic regulation
2 MIN READ
0
Seemingly futile cycles are not thermodynamically futile
3 MIN READ
0
Nutrient-dependent pheromone-controlled exercise-induced physiques
< 1 MIN READ
0
RNA-mediated species diversification from microbes to primates
3 MIN READ
0
Genotype, observed phenotype, and distinctly disordered behaviors
3 MIN READ
0
Evolutionary heritage or ecological adaptation? Racism versus reality
4 MIN READ
0
Biophysically constrained beginnings of RNA and DNA
4 MIN READ
0
Genes and Race: Human History?
2 MIN READ
0
Nutrition, pheromones and cancer (2)
2 MIN READ
0
Cell-type differentiation
2 MIN READ
0
Darwinian theories vs Darwin's facts
2 MIN READ
0
Jay R. Feierman
3 MIN READ
0
Targeting a cancer gene
2 MIN READ
0
Pheromone-controlled thermodynamics and cancer
2 MIN READ
0
Nutrient-dependent pheromone-controlled stickleback evolution
2 MIN READ
0
Understanding the role of mutations and evolution
4 MIN READ
0
Pheromones and cancer
4 MIN READ
0
Evolution at work sans random mutations (Part 2)
< 1 MIN READ
0
Human Pheromones and Consilience
2 MIN READ
0
More than speculation: adaptive evolution in species from microbes to man
2 MIN READ
0
[…] See first: RNA-mediated silencing (3) […]