Summary: Neo-Darwinian pseudoscientific nonsense should never have achieved any level of acceptance — even among scientists who are biologically uninformed science idiots.
Beyond blanket terms: Challenges for the explanatory value of variational (neuro-)ethology: Comment on “Answering Schrödinger’s question: A free-energy formulation” by Maxwell James Désormeau Ramstead et al
My summary: The commenters complain that the answer to Schrödinger’s question is framed in the context of a “Just-So” story. The theoretical construct places a “… spatio-temporal Markov blanket around the entire species of Homo Sapiens.”
Simply put, the free energy formulation does not start with the creation of the free energy. Instead the formulation invites a creationist foot to be place into the doorway of the time-space continuum without emerging on another planet. There is no other way to explain free energy-dependent changes that have already been explained by olfactory researchers who exist in the context of the space-time continuum on this planet.
The same kinds of amino acid substitutions that control the separations and interactions of side chains in fluorescent proteins also play an essential role in tuning the proposed mechanism for vibration detection—inelastic electron tunneling. Life literally runs on electron tunneling through the respiratory chain complexes in mitochondria
For comparison to this energy-dependent approach, evolution via natural selection has been reported to be a continuous “process.” The “process” must occur in the context of biophysically constrained food energy-dependent population-wide changes.
In my model, changes in the evolutionary “process” are biophysically constrained by the pheromone-controlled physiology of reproduction, which constrains viral latency. Outside the context of the energy-dependent constraints on viral latency, others are force to extend Nei’s textbook claims about all mutations in all species to the evolution of humans by including every species in the entire evolutionary tree. See: Mutation-Driven Evolution
Others have done the math. The mathematical models don’t work. No experimental evidence of biologically-based cause and effect supports the ridiculous theories.
See for comparison: Learning from Bacteria about Natural Information Processing
…not all the information required for efficient responses to all environmental conditions is stored. To solve newly encountered problems, they assess the problem via collective sensing, recall stored information of past experience, and then execute distributed information processing of the 109–1012 bacteria in the colony—transforming the colony into a “super-brain.” I show illuminating examples of swarming intelligence of live bacteria in which they solve optimization problems that are beyond what human beings can solve. This will lead to a discussion about the special nature of bacterial computational principles compared to Turing algorithm computational principles, in particular about the role of distributed information processing.
The extension from the food energy-dependent pheromone-controlled physiology or reproduction via what is known to serious scientists about the links from quantum physics to quantum computing and quantum souls involved changes in electrons to ecosystems that can now be observed via cryo-EM technology.
Even if that was not possible, theories based on mathematical models seem ridiculous at a time when serious scientists have linked multisensory integration to this report: Olfaction Warps Visual Time Perception
The added advantage that all serious scientists have is the fact that they use facts in their models, not math.
Perhaps the elegant mathematics and the extraordinary reputation of the scientists involved blinded us to what now seems obvious: the organism should never have been relegated to the role of mere carrier of its genes.
If humans are nothing more than gene carriers, experimental evidence suggests that we have not been on Earth long enough to evolve from other primates.
The findings confirm their earlier work suggesting that the majority of variants, including potentially harmful ones, were picked up during the past 5,000–10,000 years.
Other primates appear to have been on Earth long enough to be representatives of what happens due to the virus-driven degradation of messenger RNA. That also seems to be exemplified in the changes from bacteria to archaea and L-forms.
See also: Mitosis
As mitosis progresses, the microtubules attach to the chromosomes, which have already duplicated their DNA and aligned across the center of the cell. The spindle tubules then shorten and move toward the poles of the cell. As they move, they pull the one copy of each chromosome with them to opposite poles of the cell. This process ensures that each daughter cell will contain one exact copy of the parent cell DNA.
SARCASM ALERT: At what point do theorists claim that mutations lead to the evolution of differentiated cell types?
See for comparison, from The Evolution Institute:
Researchers at several [government] agencies have been censored, silenced, and otherwise intimidated; public documents on climate change have been targeted for deletion; fringe ideas in public health and the environment have been getting traction.
See also this 2014 invited review of nutritional epigenetics that was returned without review.