5hmC

DNA Methylation and organized genomes

This open access review that is linked from the title (below) will appear in the next issue of Int J Biol Sci 2015; 11(5):604-617. doi:10.7150/ijbs.11218 It is a excellent, albeit incomplete, review of how nutrient-dependent RNA-directed DNA methylation and RNA-mediated amino acid substitutions link the epigenetic landscape to the physical landscape of DNA via the DNA Methylation and organized genomes

Are viruses microRNAs? (2)

The role of microRNAs in cell type differentiation can be compared in the context of the role of viruses and mutations that cause cancer. Facts provide a basis for explaining the biological basis of epigenetically-effected cell type differentiation in species from microbes to man. But first, those who are biologically uninformed must answer the question: Are viruses microRNAs? (2)

Memory of repression and memory of behavior

H3K27me and PRC2 transmit a memory of repression across generations and during development Reported as: How epigenetic memory is passed through generations: Sperm and eggs transmit memory of gene repression to embryos Date: September 18, 2014 Excerpt: “There are dozens of potential epigenetic markers. In studies that document parent-to-child epigenetic inheritance, it’s not clear what’s Memory of repression and memory of behavior