allergic reaction

Base pairs, olfaction and RNA thermometers

RNA thermometer controls temperature-dependent virulence factor expression in Vibrio cholerae (2014) Excerpt: The stem-loop can be stabilized by strengthening the base pairing between the fourU element and SD sequence through the substitution of G-C base pairs, and this results in an elevated melting temperature (10). Conclusion: RNA thermometers represent a simple yet elegant mechanism for Base pairs, olfaction and RNA thermometers

Model vs theory: Progress report!

On June 14, 2013, 1) Nutrient-dependent/pheromone-controlled adaptive evolution: a model and 2) Mutation-Driven Evolution were published with divergent/opposite conclusions. 1) …the largest contributor to the development of our personal preferences may be the unconscious epigenetic effects of food odors and pheromones on hormones that organize and activate behavior. If so, the model represented here is Model vs theory: Progress report!

Ricki Lewis’ Time Machine

Can a Quirky Chromosome Create a Second Human Species? Excerpt 1) The first departure from the common house mouse (Mus musculus) was the “tobacco mouse” (Mus poschiavinus), described in 1869 from specimens trapped in a tobacco factory in Valle di Poschiavo, Switzerland. They had big heads and small, dark bodies. Excerpt 2) I spoke to Bear Ricki Lewis’ Time Machine

Cytogenetic approaches link biosystems to ecosystems

Cytogenetic approaches for determining ecological stress in aquatic and terrestrial biosystems (Original Russian Text E.V. Daev, A.V. Dukelskaya, L.V. Barabanova, 2014, published in Ecologicheskaya Genetika, 2014, Vol. 12, No. 2, pp. 3–12.) For comparison see this open access review: Assessing vertebrate biodiversity in a kelp forest ecosystem using environmental DNA The Russian group seemed to Cytogenetic approaches link biosystems to ecosystems

Amino acid substitutions, stress, and human behavior

Stress dynamically regulates behavior and glutamatergic gene expression in hippocampus by opening a window of epigenetic plasticity Excerpt: …33% of the human population present a BDNF Val66Met SNP that leads to a valine-to-methionine substitution in the BDNF protein at codon 66, and this SNP has been associated with increased susceptibility to development of stress-related disorders Amino acid substitutions, stress, and human behavior

Assumptions prove ignorance

Testing Einstein’s Equivalence Principle With Fast Radio Bursts Excerpt: Assuming as a lower limit that the time delays are caused mainly by the gravitational potential of the Milky Way, we prove that fast radio bursts (FRBs) of cosmological origin can be used to constrain the EEP with high accuracy. My comment: Theoretical physicists are allowed Assumptions prove ignorance

RNA-mediated cell type differentiation: Honeybee

Changes in the Gene Expression Profiles of the Hypopharyngeal Gland of Worker Honeybees in Association with Worker Behavior and Hormonal Factors Excerpt: …amino acid spacer connecting the Zn-finger motifs [49], is an early JH-response gene that mediates JH action downstream of Met [46]. My comment: RNA-mediated amino acid substitutions link the epigenetic landscape to the RNA-mediated cell type differentiation: Honeybee

Bees and primates automagically evolve

The Evolution of Social Bees Excerpt: …one key feature of increased sociality is an elaboration of gene regulation capacity. See also: From Fertilization to Adult Sexual Behavior (1996) Excerpt: …odor perception is more akin to the immune system workings where multitudes of receptors are each uniquely responsive to chemical structures (Bartoshuk and Beauchamp, 1994; Buck Bees and primates automagically evolve

MicroRNAs and memory

Diet rich in methionine may promote memory loss Excerpt: “We are looking further into epigenetic factors like microRNA and other downstream genes that could be associated with memory loss.” See also: Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems (an invited review of nutritional epigenetic) Abstract excerpt: “This atoms to ecosystems model of ecological adaptations MicroRNAs and memory