Alzheimer’s

Natural models inspire future therapeutics

Natural models inspire future therapeutics See: Screaming viruses and Alzheimer’s (1) Screaming viruses and Cancer Screaming Viruses and Alzheimer’s (2) MicroRNA biogenesis, the microRNAome, and your brainome and Reciprocal Interactions Between Gut Microbiota and Host Social Behavior We suggest that investigating these reciprocal interactions can advance our understanding of sociality, from healthy and impaired social cognition to the evolution of specific social behaviours and societal structure. There is no natural model of evolved social behavior. I suggest that all theorists…

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Part 2: Light-controlled cell biology (revisited)

Greg Bear took the lead with this approach in his novel Quantico (2006). A genetically engineered virus was used to erase the memory of a specifically targeted human population to reduce inter-ethnic conflict. [Greg Bear] …served as a consultant for NASA, the U.S. Army, the State Department, the International Food Protection Association, and Homeland Security on matters ranging from privatizing space to food safety, the frontiers of microbiology and genetics, and biological security. Greg Bear is a likely candidate for…

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Enzyme-constrained interethnic biodiversity (3)

Excerpt: Understanding a “correlational mechanism” is like understanding mutation-driven evolution. You have a mutation. You have evolution. Thus, you understand the simple-minded magic of the correlation. No energy-dependent molecular mechanisms are required. For comparison: Enzyme-constrained interethnic biodiversity is exemplified in Amish populations in the United States of America. Obviously, interethnic difference in genes matter. See: Low cancer incidence rates in Ohio Amish (2009) Why Don’t The Amish Get Cancer? (2016) See also: A null mutation in SERPINE1 protects against biological…

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Energy-dependent base editing and correction of mutations (3)

Alzheimer’s is tractable from lactose intolerance to diverticulitis and/or colon cancer, which progresses to Alzheimer’s in some people. Others ecologically adapt via a change in diet or reduction of social stress. Conclusion: Theories are the cause of all pathology. Excerpts from Energy-dependent base editing and correction of mutations (2) with a primate-specific addendum See: From Fertilization to Adult Sexual Behavior (1996) Small intranuclear proteins also participate in generating alternative splicing techniques of pre-mRNA and, by this mechanism, contribute to sexual…

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Science vs Secularism: Molecular Mechanisms or Math?

Summary: An example from ancient knowledge of trigonometry links pattern recognition as the basis for the science of creationism, and pattern recognition also is the basis for molecular biology. What form of virus-driven pathology would you most like to see eliminated from future consideration by serious scientists who know how energy-dependent RNA-mediated cell type differentiation occurs? In any case, a PubMed search for microRNA and your disease of choice will be enlightening. See for example: microRNA + Alzheimer’s or microRNA…

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George Church refutes theistic evolution

Wednesday Afternoon Lecture Series (WALS) – The future of genetic codes and BRAIN codes The NIH Director’s Wednesday Afternoon Lecture Series, colloquially known as WALS, is the highest-profile lecture program at the NIH. The future of genetic codes and BRAIN codes (video) My comment on the video: Biophysically constrained genetic codes are brain codes. They link the epigenetic landscape to the physical landscape of supercoiled DNA via metabolic networks, which link energy as information to all cell type differentiation in…

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Chirality is reality

I was banned from commenting on phys.org posts about a year ago, but recently found I could post to their FB page. This forces their “science” journalists to fight against the accurate representations of biologically-based cause and effect. Here’s an example of how they scrambled to defend their .org domain after my series of ~ 40 posts on chirality culminated with this one from January 1, 2017: Energy-dependent chirality (2) They linked light-induced changes in gamma oscillations (20-50 Hz) to…

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Energy-dependent alternative splicings 1996 – 2016

Highlights: 1) Alternative splicings of messenger RNA link the sun’s anti-entropic virucidal energy as information to DNA repair. 2) DNA repair links fixation of amino acid substitutions in supercoiled DNA to healthy longevity. 3) Supercoiled DNA protects all organized genomes from virus-driven energy theft and genomic entropy. 4) Genomic entropy is less likely to occur in the context of the physiology of reproduction and transgenerational epigenetic inheritance of ecologically adapted morphological and behavioral phenotypes. 5) Preventing virus-driven energy theft from…

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Hydrogen-atom energy in DNA base pairs

See also: Consciousness is simply food rearranged Role of Double Hydrogen Atom Transfer Reactions in Atmospheric Chemistry Abstract excerpt:  Hydrogen atom transfer (HAT) reactions are ubiquitous and play a crucial role in chemistries occurring in the atmosphere, biology, and industry. My comment: The link from physics to chemistry and the conserved molecular mechanisms of biologically-based RNA-mediated cell type differentiation has been the focus my works for more than 20 years, even before I knew what I would need to explain…

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Ignore the evidence: Rachel Feltman

“There is incontrovertible evidence that Alzheimer’s Disease has a dormant microbial component. We can’t keep ignoring all of the evidence” –Professor Douglas Kell, Manchester University Experts Say There’s a Herpes-Alzheimer’s Link Excerpt: …herpes has been linked to damage in the central nervous system and the limbic system, which is associated with mental decline and personality changes, the Telegraph reported. The experts called for a deeper investigation into the connection. Calm down: Herpes probably isn’t going to give you Alzheimer’s Excerpt:…

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  • Randomness and Divine Providence
    A Q&A on randomness and God’s providence …the main goal is to really put together a collection of scholarly studies of these issues: physicists, biologists, […]
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