amino acid substitution

MicroRNA-mediated existential threats (2)

April 22, 2022
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Nutrigenomics, Pharmacogenomics, Physics, replication timing, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations
No Comments

On 6/26/19, a friend and I stopped at the Scopes Museum in Dayton, Tennessee to make sure I could view this presentation on my laptop computer via a hotspot wi-fi connection. See: Genome-Wide Study Reveals a Novel Regulatory Pathway: Translation Affects mRNA Stability in a Codon-Dependent Manner 6/26/19 (available for free on demand with registration). I may try to find my pictures, or my on-location video to show that, as predicted, the presentation put an end to all the nonsense…

Read More

Orchestrated death: Kevin J. Mitchell

October 13, 2021
James Kohl
Adaptations, Autophagy, base editing, biophotonics, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Physics, replication timing, RNA Directed, RNA interference, Subatomic
No Comments

For another example of how stupid theorists orchestrate unnecessary suffering and premature death, see: The Archean origin of oxygenic photosynthesis and extant cyanobacterial lineages 9/29/21 reported as Genomic analysis pinpoints early date for the evolution of photosynthesis 10/6/21, which was the day after NIH director, Francis S. Colllins resigned. The evolution of oxygen-generating photosynthesis “is probably the single most important event that ever occurred on Earth, aside from the origin of life itself,” says Gregory Fournier, a geobiologist at the…

Read More

Quantum Darwinism (5)

April 15, 2021
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, Cytosis, Diseases & Disorders, Ecology, microRNA editing, Model Organisms, Physics, RNA Directed, RNA editing, RNA interference, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Subatomic
No Comments

See with my added emphasis: Parallel genetics of regulatory sequences using scalable genome editing in vivo 4/13/21 [Energy-dependent biophysically-constrained microRNA-mediated] Regulatory elements must ultimately be understood within their genomic environment and development- or tissue-specific contexts. Gene-centric theorists are too stupid to start with God’s Creation of energy, which must be linked from regulatory elements to regulation of the genomic environment before the effects of energy can be understood in any context whatsoever. See for context: Energy as information and constrained…

Read More

Impeaching the God of Abraham (5)

February 23, 2021
James Kohl
Adaptations, Alternative Splicings, base editing, Ecology, Light Energy, microRNA editing, Model Organisms, Physics, RNA Directed, RNA editing, RNA interference, RNA–Mediated Epigenetic Heredity
No Comments

More than 116,000 indexed published works link sunlight from microRNA biogenesis to biophysically constrained viral latency across kingdoms via the energy-dependent assembly of the microRNA-RNA-peptide nanocomplex. But see: Experts say there’s no medical basis for Trump’s suggestion that sunlight, disinfectants may treat coronavirus 4/24/21 Jonathan Reiner, professor of medicine at The George Washington University Hospital, said there’s no medical basis for Trump’s statements about sunlight. See for comparison: Specific enzymatic amplification of DNA in vitro: the polymerase chain reaction (1986)…

Read More

Epigenetic inheritance of spatiotemporal regulation (3)

May 24, 2018
James Kohl
Adaptations, Alternative Splicings, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, microRNA editing, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA interference, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA–Mediated Epigenetic Heredity, Variations, What's in the News
No Comments

Summary: Wen Zhou’s group has linked the creation of anti-entropic virucidal light from the quantized energy-dependent creation of microRNAs to the food energy-dependent neuroendocrine origins of human behavior via the pheromone-controlled physiology of reproduction and fixation of RNA-mediated amino acid substitutions in species from microbes to humans. Simply put, she has linked quantum physics to quantum souls via what is known about biophysically constrained viral latency in the context of the cell biology game Cytosis and the future of biology.…

Read More
Plenty of Room at the Bottom

Environmental selection is natural selection (2)

April 26, 2018
James Kohl
Adaptations, base editing, biophotonics, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
No Comments

I believe that if you put enough biologically uniformed theorists in the same room, they will invent more theories to support the pseudoscientific nonsense they have touted in the past. See for example: Environmental selection during the last ice age on the mother-to-infant transmission of vitamin D and fatty acids through breast milk Acknowledgments The synthesis presented here is a product of the American Association for the Advancement of Science’s 2017 annual meeting, as the ideas came together in the…

Read More

Odor activation of ATP (2)

March 26, 2018
James Kohl
Adaptations, Diseases & Disorders, Ecology, Model Organisms, Physics, RNA Directed, Subatomic
No Comments

Metabolic Regulation of Cytoplasmic DNA Synthesis (1974) The curve that results when the rate of DNA synthesis is plotted as a function of ATP concentration is sigmoidal, suggesting that more than one site on the enzyme interacts with ATP and that these sites are acting cooperatively. Odor activation of ATP is the obvious link to RNA-mediated feedback loops that control the food energy-dependent pheromone-controlled physiology of reproduction via the rate of DNA repair in species from microbes to humans. See:…

Read More
Lethal virus kills 5 billion people?

The “walking fish” walks straight from quantum physics to quantum souls (5)

January 4, 2018
James Kohl
Adaptations, Autophagy, biophotonics, Diseases & Disorders, Ecology, RNA Directed
No Comments

Evolutionary determinants of genome-wide nucleotide composition January 1, 2018 1) They place their thoughts about mutation rates into the context of compatibility with mutational spectra. 2)They claim the mutation rate can be linked to mutational spectra that may be free to wander across evolutionary time. 3) They ignore facts that link the energy-dependent maintenance of a suppressed constant genome-wide deleterious rate that obviously occurs in the context of the Virus-mediated archaeal hecatomb in the deep seafloor 4) They eliminate the…

Read More

A Mathematical Model Links Quantum Physics to Quantum Souls (1)

December 28, 2017
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic
One Comment

Historical facts: All energy-dependent cell type differentiation is biophysically constrained by the de novo creation of microRNAs and enzymes that metabolize food and drugs. All food energy-dependent metabolism occurs in the context of microRNA-mediated cause and effect and the physiology of pheromone-controlled reproduction. The food energy-dependent pheromone controlled physiology of reproduction in bacteria links what organisms eat to the transgenerational epigenetic inheritance of their morphological and behavioral phenotypes. The virus-driven degradation of messenger RNA has been linked to all pathology…

Read More
RSS Perfuming the Mind