Amino Acid

Biologically uninformed biologists fight back and lose

Novel layers of RNA polymerase III control affecting tRNA gene transcription in eukaryotes 22 Feb 2017 A subset of tRNA genes shows low responsiveness to both environmental and cellular signals. Notably, this group contains at least one tRNA for each amino acid. Together these findings suggest the existence of a basal subset of housekeeping tRNA genes [36]. This concept is consistent with the mode of Maf1-mediated repression of actively transcribed tRNA genes in human cells subjected to serum starvation [104].…

Read More

Francis S. Collins refutes theistic evolution

Criticisms of the nutrient-dependent pheromone-controlled evolutionary model Based on his writings, both published and unpublished, James Kohl presents an unsupported challenge to modern evolutionary theory and misrepresentations of established scientific terms and others’ research. — Andrew Jones, BA Editor’s note The 2013 review article by James Vaughn Kohl published in Socioaffective Neuroscience & Psychology and criticized in the above Letter to the Editor was subjected to standard peer review and the revised version was accepted by me after it had…

Read More

Physicists: Desperate Acts (revisited)

Physicists: Desperate Acts Light-induced endogenous RNA interference in bioluminescent microbes links Schrodinger’s claims in “What is LIfe?” (1944) from a light-to-chemical pathway of information exchange in all living genera via amino acid substitutions in supercoiled DNA. All subsequent works on the evolutionary synthesis failed to link  the anti-entropic virucidal energy of sunlight to Darwin’s “conditions of life” from the claims of Schrodinger (1944) or the claims of any other serious scientist. Indeed, in the case of higher animals we know…

Read More

Energy-dependent chirality

See also: Achiral glycine Summary: Virus-driven energy theft alters the interactions between physics and chemistry that maintain biophysically constrained biodiversity. That’s how viruses are linked from mutations to all pathology. Nutrient energy-dependent changes in the context of the pheromone-controlled physiology of reproduction biophysically constrain biodiversity via the fixation of amino acid substitutions in supercoiled DNA, which protects organized genomes from virus-driven pathology. Chirality (chemistry) Two enantiomers of a generic amino acid that is chiral The chirality of amino acids is energy-dependent…

Read More

Anti-entropic virucidal energy as information

 How Can Physics Underlie the Mind? Top-Down Causation in the Human Context by George Ellis (p. 404) Repeated thousands of times over geological timescales, it is this relentless repetition of the top-down process of adaptive selection [29] that gives Darwinian evolution its enormous power. Theorists never seem to ask questions about where the enormous power came from or where it goes when organisms die. They seem to think that relentless repetition of biophysically constrained energy-dependent protein biosynthesis and degradation automagically…

Read More

Energy-dependent natural translational selection

17th Century Variola Virus Reveals the Recent History of Smallpox …our data clearly show that the VARV lineages eradicated during the 20th century had only been in existence for ∼200 years… Reported as: Smallpox, once thought an ancient disease, may have emerged in more recent times … smallpox virus evolved into two circulating strains, variola major and minor, after English physician Edward Jenner famously developed a vaccine in 1796. How does any virus-driven pathology evolve into two different strains and…

Read More

Energy-dependent de novo creation and neurogenesis

See also: Tasting light links energy from creation to adaptation Developmentally defined forebrain circuits regulate appetitive and aversive olfactory learning reported as: When neurons are ‘born’ impacts olfactory behavior in mice My summary: The de novo creation of different cell types is placed into the context of their energy-dependent birth and the transgenerational epigenetic inheritance of molecular mechanisms that link virus-driven energy theft to all pathology via olfaction, food odors, and human pheromones. See for comparison: Metabolism and neurogenesis …it…

Read More

Theories vs facts about polycombic adaptation

See: Demoncrats fight polycombic ecological adaptation Exosomes as miRNA Carriers: Formation–Function–Future Important aspects will be highlighted as a take-home message (THM) at the end of each paragraph. THM: Extracellular vesicles transport miRNA in a paracrine and endocrine manner. Questions regarding the cellular options of producing either microvesicles or exosomes and their difference in miRNA composition and number are still unknown. In my 2014 invited review, the four F’s, Formation–Function–Future and Copulation were included in details about how the nutrient energy-dependent…

Read More

RNA-mediated terrorism

Obama Advisers Urge Action Against CRISPR Bioterror Threat For the past two decades, the government has focused its biodefense efforts on a list of known pathogens—such as anthrax, smallpox, and Ebola—declared by the Department of Health and Human Services and Department of Agriculture to have the “potential to pose a severe threat to public health and safety.” Government-funded research on these pathogens receives special scrutiny, and the National Institutes of Health limits researchers from conducting experiments that could make certain…

Read More

Energy-dependent maternal-to-zygotic transition

Small Non-coding RNAs Associated with Viral Infectious Diseases of Veterinary Importance: Potential Clinical Applications ON 11/14/16 The co-author Mohamed Samir wrote:  Because our article is among the top 25% most viewed and downloaded articles in the third quarter of 2016 in “Frontiers in Veterinary Science”, The editor of the journal has invited me to host and moderate a new research topic in his journal about miRNAs in veterinary filed. Thanks God. The topic is virtually guaranteed to bring out the…

Read More