Amino Acid

RNA-mediated retrotransposon-mediated biodiversity

Retrotransposons (also called transposons via RNA intermediates) are genetic elements that can amplify themselves in a genome and are ubiquitous components of the DNA of many eukaryotic organisms. See also: A Single Amino Acid Change in the Yeast Retrotransposon Ty5 Abolishes Targeting to Silent Chromatin Excerpt: Target site biases observed among retroviruses and retrotransposons are thought to be the consequence of interactions between the retroelement integration complex and chromosome-localized proteins. My comment: Clearly, the way to make scientific progress is…

Read More

Keep the gay gene theory?

See first: Supercoiled DNA constrains virus-driven genomic entropy The data that links small molecules, such as microRNAs, from metabolic networks to genetic networks, makes the claims of neo-Darwinian theorists the theme of this parody. It is an accurate representation of how nutrient-dependent base pair changes link ecological variation to ecological adaptation and all biomass on earth via what is currently known to serious scientists about base pair changes and RNA-mediated DNA repair. For example: This gene-centric theory has been eliminated.…

Read More

Let there be anti-entropic light (2)

Predicted Inactivation of Viruses of Relevance to Biodefense by Solar Radiation (2005)Excerpt: Sunlight or, more specifically, solar UV radiation (UV) acts as the principal natural virucide in the environment. UV radiation kills viruses by chemically modifying their genetic material, DNA and RNA. See also: Let there be anti-entropic light (1) Excerpt: Nutrient-stress and social stress contribute to the accumulation of viral miRNAs that would typically be prevented by nutrient-dependent pheromone-controlled feeback loops that link food odors and social odors to…

Read More

Microbes to humans 2015 Nobel Prize

3 Scientists Win Nobel Prize in Medicine for Parasite-Fighting Therapies Excerpt 1) Success in antimalarial therapy depends on how clever scientists are in using combinations of drugs. Excerpt 2) Dr. Omura played down his accomplishments, saying, “I merely borrowed the power of microbes.” My comment: These two excerpts appear within the context of three paragraphs that clearly link RNA-mediated cell type differentiation in species from microbes to humans. The context attests to what at first may appear to be a…

Read More

Is mainstream science in “Science” pseudoscience?

See: Single neuron may carry over 1,000 mutations (with my comments),  A natural history of neurons: Diverse mutations reveal lineage of brain cells (with my comments), and Study examines scale of gene mutations in human neurons, All three of the links above are to reports on the study results published as: Somatic mutation in single human neurons tracks developmental and transcriptional history Excerpt 1) We also observed a signature of methylated cytosine (meC) to thymine (T) transitions (fig. S8), which…

Read More

Alternative pre-mRNA splicing and ecological adaptation

This startup thinks it can speed up a cure for cancer by bringing scientific research into the YouTube era Excerpt: The current scholarly publishing model did not allow me to present the research I was doing. I created [Figshare] initially out of purely selfish reasons and I spent my evenings and weekends creating a platform that allowed me show, in a super simple way, data sets, and videos to put me ahead of the rest of my peers. I’ve used…

Read More

“New” quantum biology. Pirating the old

Jim Al-Khalili is a nuclear physicist. Luca Turin is a biologist. Both presenters link Schrödinger’s claims in What is Life? Which one knows most about it? Jim Al-Khalili  frames his presentation in the context of evolutionary theory. See the text or the 20-minute Video presentation: Jim Al-Khalili: How quantum biology might explain life’s biggest questions Luca Turin frames his presentation in the context of what is known to serious scientists about the biophysically constrained chemistry of nutrient-dependent RNA-mediated protein folding. See also: …

Read More

Anti-entropic containment of energy: symbiosis 1.0

Scientists explore the origins of energy in chemical reactions using experimental quantum chemistry Excerpt: One thing that all chemical reactions have in common—whether they are the reactions that take place inside a battery, the metabolic reactions inside a living organism, or the combustion reactions that cause an explosion—is that they all involve some kind of change in energy. My comment: Therein lies the problem with attempts by pseudosceintists to link nutrient energy from ecological variation to epigenetically-effected ecological adaptation, which…

Read More

Eibi Nevo gets it wrong

Eibi Nevo: Evolution, Let’s Get It Right, It’s the “Basis of Everything” Excerpt: “The best we can know about origin of life may be from viruses we are looking at. They could have been at the origin of life before they parasitized it, or became symbionts in prokaryotes and eukaryotes. . . .” My comment: Let’s really get it right. Were viruses created first or did they parasitize all creation via perturbation of nutrient-dependent RNA-mediated protein folding in the context…

Read More

The stability of organized genomes (3)

See also: The stability of organized genomes; The stability of organized genomes (2) Nutrient-dependent/pheromone-controlled adaptive evolution: a model Excerpt from 6/14/13  …the epigenetic ‘tweaking’ of the immense gene networks that occurs via exposure to nutrient chemicals and pheromones can now be modeled in the context of the microRNA/messenger RNA balance, receptor-mediated intracellular signaling, and the stochastic gene expression required for nutrient-dependent pheromone-controlled adaptive evolution. Global relationships in fluctuation and response in adaptive evolution Preprint pdf opens here Excerpt: It should…

Read More