Of Cells and Limits Leonard Hayflick has been unafraid to speak his mind, whether it is to upend a well-entrenched dogma or to challenge the federal government. At 86, he’s nowhere near retirement. By Anna Azvolinsky | March 1, 2015 Excerpt: The rejection letter came from Francis Peyton Rous who received the Nobel Prize a … Rejecting what is known about viral microRNAs and nutrient-dependent microRNAs
See for review: Let there be anti-entropic light (1) Squid are hyper-editors when it comes to RNA This is a great summary of what is currently known about anti-entropic light and nutrient-dependent RNA-mediated pheromone-controlled cell type differentiation. Excerpt: “During RNA editing, specific enzymes alter nucleotides in mRNA transcripts so that the resulting protein differs … Reverse phosphorylation
Discoveries in 3-D Genome Make-Up and Genetic Changes: Clarification of differences amidst chromosome pairs and how gene expression is effected by chromosome folding Excerpt: “…offers a useful guide for future studies of the epigenome’s function in our evolution and diseases that beset us.” My comment: The guide is also useful because it shows how the … From 3-D to epigenetically-effected 4-D genome make-up
Summary: Light-induced amino acid substitutions link cell type differentiation in plants to nutrient-dependent pheromone-controlled reproduction in animals via the biophysically constrained chemistry of protein folding. Protein folding is perturbed by mutations that limit the ability of organisms to adapt to ecological variation. Viruses contribute to mutations. The sun’s biological energy appears to supply the anti-entropic … Let there be anti-entropic light (1)
1) Arguments in the evo-devo debate: say it with flowers! Abstract excerpt: A key question in evolutionary developmental biology is how DNA sequence changes have directed the evolution of morphological diversity. The widely accepted view was that morphological changes resulted from differences in number and/or type of transcription factors, or even from small changes in … Imagining that data historically supports evolutionary theory
Scientific Seeker Stuart Kauffman on Free Will, God, ESP and Other Mysteries By John Horgan | February 4, 2015 Excerpt: Horgan: What do you make of the antipathy toward religion expressed by Richard Dawkins and other “New Atheists?” Kauffman: … moral behavior requires no belief in God. Morality probably evolved in Paleolithic to some extent. But … Atheism: Arrogant, useless, and divisive ignorance
Exploring the Epigenome A National Institutes of Health-funded consortium publishes 111 reference maps of DNA and histone marks. By Jenny Rood | February 18, 2015 Excerpt: “All our cells have a copy of the same book, but they’re all reading different chapters, bookmarking different pages, and highlighting different paragraphs and words.” These chemical bookmarks, such … The anti-entropic force of "Nature"
Anti-inflammatory mechanism of dieting and fasting revealed Summary: Researchers have found that a compound produced by the body when dieting or fasting can block a part of the immune system involved in several inflammatory disorders such as type 2 diabetes, atherosclerosis, and Alzheimer’s disease. My comment: For the obvious link from nutrition and exercise to … Nutritional epigenetics, exercise, and immune system integrity
