anti-entropy Archives - RNA-Mediated

Do not miss the misrepresentations

March 8, 2016

Adaptations, Diseases & Disorders, Ecology, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, RNA Directed, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations

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PLOS Biology ICYMI: February’s Five January 25, 2016 Reported as 1) “… they hypothesise short bursts of rapid species diversification, such as after the famous mass extinction event…” January 11, 2016 Reported as 2) “…a newly identified protein, Wuho (WH), regulates the activity of FEN1 when around a replication fork, ensuring it does more good acting as a flap endonuclease than damage as a gap endonuclease.” January 7, 2016 Reported as 3) “Exosomes Protect and Perpetuate Chemical Attractants” February 12,…

Ecological law, cooperation, and DNA repair

January 10, 2016

James Kohl

Adaptations, biophotonics, Ecology, Light Energy, Model Organisms, Neuronal Plasticity, Physics, RNA Directed, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations

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Ecological laws: what would they be and why would they matter? Abstract excerpt: … I argue, the existence of ecological laws would make ecological explanations irreducible to even the most complete possible physical explanations of the same phenomena. Ecological laws would make ecology genuinely autonomous from physics. My comment: This is a fool’s argument. Serious scientists know physics and chemistry must be linked to biophysically constrained nutrient-dependent RNA-mediated protein folding chemistry. The links must be placed into the context of…

Viruses, amino acids, and somatic cell types (3)

August 1, 2015

James Kohl

Adaptations, Alternative Splicings, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, RNA Directed, Variations

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A co-author of our 1996 Hormones and Behavior review of hormone-organized and hormone-activated behaviors gave her permission to add additional items of interest to this series of blog posts about viruses, amino acids, and somatic cell types. Teresa Binstock is largely responsible for my knowledge of RNA-mediated cell type differentiation. She introduced me and others to the complexity in the section of our review with the title Molecular epigenetics. Excerpt: It is now understood that certain genes undergo a process…

Living the life that randomness created? (Sarcasm alert)

June 3, 2015

James Kohl

Adaptations, Ecology, Light Energy, Physics, RNA Directed, Variations

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The Living Set Mathematical and computational approaches are making strides in understanding how life might have emerged and organized itself from the basic chemistry of early Earth. By Wim Hordijk | June 1, 2015 Excerpt: Put some E. coli in a dish with appropriate nutrients, and after a few days the dish will be teeming with new bacterial offspring. My comment: Put some genetically altered P. fluorescens in a dish and leave them “over-the-weekend” with their missing flagella over-the-weekend. Forget…

RNA directed DNA methylation and cell types

March 12, 2015

James Kohl

Adaptations, Alternative Splicings, Ecology, Human Pheromones, Model Organisms, Nutrigenomics, RNA Directed

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Cell type differentiation is included in all topics in biology, which is why it is important to understand what is currently known about top-down causation in the context of physics and chemistry. Taken together, physics, chemistry, and the conserved molecular mechanisms of biology link Drosophila to Octopuses and all other species on this planet via RNA-directed DNA methylation and RNA-mediated amino acid substitutions that differentiate cell types. See for examples: Let there be anti-entropic light (1) An antagonist led me…