biodiversity

Cryo-EM: More than a suggestion

October 24, 2017
James Kohl
Adaptations, Diseases & Disorders, Ecology, Variations
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Cryo-EM imaging suggests how the double helix separates during replication October 23, 2017   Details in the structure not previously seen reveal how various protein subunits of the twin hexamers latch on to the double helix, via tiny loop-like structures. What are the subunits of protein? The subunits of proteins are called amino acids. I will not stop saying that cryo-EM links what is known about energy-dependent changes in the microRNA/messenger RNA balance from electrons to ecosystems via fixation of…

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Long-term adaptation replaces evolution (2)

October 23, 2017
James Kohl
Adaptations, Alternative Splicings, Autophagy, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Model Organisms, Nutrigenomics, Physics, RNA-directed DNA methylation, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity
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The food energy-dependent “doubling up” on ‘junk DNA’ is biophysically constrained by the physiology of pheromone-controlled reproduction. The metabolism of food to species-specific pheromones links the conserved molecular mechanisms of RNA-mediated cell type differentiation in all individuals of all living genera to healthy longevity via what is known about amino acid substitutions in supercoiled DNA, which link energy-dependent changes in chirality to autophagy. Supercoiled DNA is far more dynamic than the ‘Watson-Crick’ double … Researchers have imaged in unprecedented detail the…

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Predicting who wins the 2017 Nobel Prizes (7)

October 6, 2017
James Kohl
Adaptations, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Physics, RNA Directed, RNA-mediated toxicity, Subatomic
One Comment

Conclusion: The biggest threat to humanity is not the “Big Bang” theory of creation or the “Big Bang” theory of how life on Earth might end after an explosion of cosmic proportions. The biggest threat has always been “human idiocy.” 2017 Nobel Peace Prize Awarded to International Campaign to Abolish Nuclear Weapons “for its work to draw attention to the catastrophic humanitarian consequences of any use of nuclear weapons and for its ground-breaking efforts to achieve a treaty-based prohibition of…

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Predicting who wins the 2017 Nobel Prizes (4)

October 3, 2017
James Kohl
Adaptations, Autophagy, biophotonics, Ecology, Light Energy, Physics, RNA Directed, Subatomic, Variations
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As you wait to learn who won the 2017 Nobel Prize in Physics and in Chemistry, please consider how these recent reports will be linked from electrons to ecosystems. Every aspect must start with the creation of energy, which must link chemistry to biophysically constrained biologically based life on Earth in the context of the physiology of pheromone-controlled reproduction and Schrodinger’s claims in “What is Life? (1944). Without mention of the anti-entropic virucidal energy of sunlight, the theories of physicists…

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For God and Country

Dispelling the ignorance of theorists

September 22, 2017
James Kohl
base editing, RNA Directed, RNA editing, RNA-directed DNA methylation
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American Legion Riders (Riding for God and Country on 9/9/17) Summary: The highest-order of energy-dependent pre-assembly of respiratory chain complexes allows mitochondria to respond to energy-requiring conditions. There is no such thing as the emergence of energy, self-assembly, self-organization or any other pseudoscientific nonsense touted by theorists. Their theories exemplify what Richard P. Feynman referred to as “human idiocy.” That is why I refer to theorists who argue with me as “biologically uninformed science idiots.” Friends sometimes tell me I…

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For God and Country

Sci-Hub vs limits on the dissemination of information

September 20, 2017
James Kohl
Adaptations, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, RNA Directed, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations, What's in the News
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The ideology of “Americanism” is not consistent with the tactics of academics and politicians that constrain release of accurate information about  biologically-based cause and effect. …Americanism is an ideology, or belief in devotion, loyalty, or allegiance to the United States of America, or to its flag, traditions, customs, culture, symbols, institutions, or form of government.[2] In the words of Theodore Roosevelt, “Americanism is a question of spirit, conviction, and purpose, not of creed or birthplace.”[3] Americanism has two different meanings.…

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Automagical protein creation sans energy

August 10, 2017
James Kohl
Adaptations, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Physics, RNA Directed, RNA-directed DNA methylation, RNA–Mediated Epigenetic Heredity
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Summary: The creation of the enzyme is linked to the evolution of all biodiversity via the creation of the enzyme and mutations. See for comparison: Neuronal-expressed microRNA-targeted pseudogenes compete with coding genes in the human brain. Listen to this song about Santa Claus and note that he sees you when you’re sleeping and somehow unconsciously determines if you’ve been good or bad. Santa Claus may know that the sense of smell has repeatedly been linked to effects on hormones and unconscious…

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Solar analemma with a total solar eclipse

August 8, 2017
James Kohl
Adaptations, biophotonics, Ecology, Light Energy, Physics
No Comments

Energy as Information and Constrained Endogenous RNA Interference (video) The energy as information comes from the sun. The sun’s anti-entropic virucidal energy has been linked to the creation of microRNAs and to all biophysically constrained biodiversity on Earth via the physiology of food energy-dependent pheromone-controlled reproduction. See also: The link from the sun’s anti-entropic virucidal energy to all biodiversity via the physiology of reproduction may have been better understood from representations in Biblical Genesis than any other post hoc representations.…

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The Origin of Information (4)

August 4, 2017
James Kohl
Adaptations, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
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Summary: Others have learned that the energy in a hydrogen atom must be linked to all biodiversity on Earth. The question is: “Where did the energy in the hydrogen atom come from?” See: The Origin of Information (3) Finally, someone is asking questions that can be summarized in one question (see below). Until now, on the International Society for Human Ethology’s Yahoo group, and elsewhere, the moderator: Jay R. Feierman has prevented the dissemination of accurate information on this topic.…

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Energy-dependent physical and biophysical constraints (8)

July 27, 2017
James Kohl
Adaptations, Alternative Splicings, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA–Mediated Epigenetic Heredity, Variations
One Comment

Summary: The role of vitamin C in the treatment of pain: new insights links what is known about the “superfood” Spirulina (blue-green algae), which is grown in marine and freshwater environments, to the stability of all organized genomes via its biological activities, such as antioxidant, anti-diabetic, cholesterol-controlling and insulin resistance effects. The biological activities are energy-dependent and they link the anti-entropic virucidal energy of sunlight to all biodiversity via the pheromone-controlled physiology of reproduction and microRNAs in plants and animals.…

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