bioinformatics

Sunlight, hydrophobicity and biodiversity (1)

A five-coordinate Mn(iv) intermediate in biological water oxidation: spectroscopic signature and a pivot mechanism for water binding 11/17/15 …a multi-step process that involves the redox-active tyrosine residue and includes oxidation and deprotonation of the catalytic cluster, as well as the binding of a water molecule. See for comparison: Molecular Diagnostics April 6-7, 2016 What is Sunlight, hydrophobicity and biodiversity (1)

MicroRNAs as therapeutic agents

Excerpt: See for comparison: Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems (2018) Twitter is blocking my tweets when I include links to this open access article about the fact that microRNAs buffer genetic variation. MicroRNAs as therapeutic agents: The future of the battle against cancer MicroRNAs bind to their target mRNAs to act as MicroRNAs as therapeutic agents

Energy-dependent RNA methylation (8)

Multiplexing Genetic and Nucleosome Positioning Codes: A Computational Approach Mutation Monte Carlo method (MMC): Excerpt: The mutation moves change the bp sequence but keep the DNA configuration fixed. Both moves change the energy, Eq (1), of the two bp steps involved. My comment: Moves that change energy cost energy. Attributing energy-dependent changes in base pairs Energy-dependent RNA methylation (8)

Molecular Microbial Ecology

Second Genome Solutions Excerpt: Todd DeSantis is Second Genome Co-founder and Senior Director of Bioinformatics. Todd has 17 years of experience designing and implementing bioinformatics solutions for analyzing microbial community dynamics. At Lawrence Berkeley National Laboratory he led the development of novel microbiome assays and analysis pipelines as a Molecular Microbial Ecology Software Developer. He Molecular Microbial Ecology