biophysical

A Darwinian pediatrician and expected life span

See also: A 5-10K comparison of design priciples to evolution CEM Thursday Seminar – Paul Turke Excerpt: The human immune system reboots every generation. It’s a lifelong process, but much of it is accomplished before birth. My comment: The world’s first Darwinian pediatrician appear to know nothing about nutrient-dependent RNA-mediated cell type differentiation. See for comparison: Regulating S-adenosine-methionine (SAM) levels to extend life span Excerpt: Limiting S-adenosyl-methionine (SAM) synthesis, the first metabolic reaction of dietary methionine, extends longevity in Caenorhabditis elegans…

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RNA-protein interactions reveal biophysical to ecological landscapes

Quantitative analysis of RNA-protein interactions on a massively parallel array reveals biophysical and evolutionary landscapes RNA-protein interactions are tethered to DNA via ultra-high-throughput measurement of the RNA-protein interactions that link amino acid substitutions to cell type differentiation. Differences in affinity are often driven by sequence-specific changes in both association and dissociation rates that rapidly link bio-physical constrained RNA-mediated protein folding to models that provide “…generalizable insight into the biophysical basis and evolutionary consequences of sequence-function relationships.” This is the generalizable…

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Soft atheism: a case for Creation

The Case for ‘Soft Atheism’ By GARY GUTTING   Excerpt: “…much as I admire Dawkins’s work in evolutionary biology and in enhancing the public understanding of science…” My comment: The case against evolution. Quantitative analysis of RNA-protein interactions on a massively parallel array reveals biophysical and evolutionary landscapes Biophysical constraints that enable the intermolecular tethering of RNA to DNA also link the epigenetic landscape to the physical landscape of DNA via the conserved molecular mechanisms of RNA-mediated events in species from…

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