See also: Neuroplasticity Thanks to Teresa Binstock for calling my attention to this: Thanks to Anna Di Cosmo for calling the attention of others to this: My comment: Attempts to explain the “binding problem” of integration in the context of ecoimmunology and disease ecology compared to emergence and evolution are examples of how much … Theorists can’t understand biology
Watch what happens after the folks at “Complex Biological Systems Alliance” and George Ellis have realized the seriousness of their failure to link the sun’s biological energy from top-down causation in an atoms to ecosystems model of how metabolic networks and genetic networks are linked to the supercoiled DNA that protects organized genomes from virus … Too complex for the Complex Biological Systems Alliance
The protein arginine methyltransferase PRMT5 promotes D2-like dopamine receptor signaling Excerpt 1) The addition of a methyl group to an arginine residue can remove a hydrogen bond donor and decrease the electrostatic surface potential at the residue, resulting in a change in size and hydrophobicity that can affect its interaction with binding partners (21). Excerpt … Receptor methylation controls behavior
Serine … is one of the proteinogenic amino acids. [It]… is classified as a polar amino acid. My comment: Serine synthesis in the body is linked to glycine, which also may be naturally produced when UV light illuminates simple ices (e.g., combinations of water, methanol, hydrogen cyanide, and ammonia). That suggested to some people that … Controled Stem Cell Expansion
Unconstrained cranial evolution in Neandertals and modern humans compared to common chimpanzees Excerpt: “…cranial differentiation in common chimpanzees has been restricted by stabilizing natural selection.” See for comparison: Mutation-Driven Evolution Excerpt: “…genomic conservation and constraint-breaking mutation is the ultimate source of all biological innovations and the enormous amount of biodiversity in this world.” See also … Biophysically constrained or unconstrained?
Retrotransposons (also called transposons via RNA intermediates) are genetic elements that can amplify themselves in a genome and are ubiquitous components of the DNA of many eukaryotic organisms. See also: A Single Amino Acid Change in the Yeast Retrotransposon Ty5 Abolishes Targeting to Silent Chromatin Excerpt: Target site biases observed among retroviruses and retrotransposons are … RNA-mediated retrotransposon-mediated biodiversity
The Vital Question: Energy, Evolution, and the Origins of Complex Life Excerpt: Building on the pillars of evolutionary theory, Lane’s hypothesis draws on cutting-edge research into the link between energy and cell biology in order to deliver a compelling account of evolution from the very origins of life to the emergence of multicellular organisms while … Energy and evolution: another opinion?
Predicted Inactivation of Viruses of Relevance to Biodefense by Solar Radiation (2005)Excerpt: Sunlight or, more specifically, solar UV radiation (UV) acts as the principal natural virucide in the environment. UV radiation kills viruses by chemically modifying their genetic material, DNA and RNA. See also: Let there be anti-entropic light (1) Excerpt: Nutrient-stress and social stress … Let there be anti-entropic light (2)
There are foundations of epigenetics and fundamentals of molecular mechanisms. They have been detailed in this atoms to ecosystems model of RNA-mediated cell type differentiation. Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems. I have never seen anyone mention the “foundamentals” of epigenetics. It appears the word has been invented. Similarly, the word “mutation” was … Foundamentals of theory
See: Single neuron may carry over 1,000 mutations (with my comments), A natural history of neurons: Diverse mutations reveal lineage of brain cells (with my comments), and Study examines scale of gene mutations in human neurons, All three of the links above are to reports on the study results published as: Somatic mutation in single … Is mainstream science in “Science” pseudoscience?
