biosynthesis

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The MicroRNAome Strikes Back: A Sokalian hoax (4)

In this Sokalian hoax series, all food energy-dependent pheromone-controlled biodiversity has clearly been linked from the speed of light on contact with water to biophysically constrained viral latency in all genera via the physiology of reproduction and autophagy, the innate phage defense mechanism. Will water link RNA modifications to stem cell self-renewal, or will light-activated endogenous substrates and biophysically constrained RNA-mediated amino acid substitutions be tossed into the brickyard for the win? I reiterate the most obvious facts by mentioning…

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God’s shrinking role in salvation

God’s shrinking role in salvation can temporarily be placed into the context of what serious scientists are reporting for comparison to the claims of pseudoscientists. See: Quantum Simulation (free download) It presents several examples of experiments using both density and momentum imaging and quantum gas microscopy to study the motion of atoms in optical lattices. The energy-dependent motion of atoms must be linked to ecosystems by the physiology of pheromone-controlled reproduction in all living genera. That fact requires extended consideration…

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Theistic evolutionists fight back and lose (2)

For a historical perspective on the amount of ignorance theistic evolutionists and atheists have repeatedly displayed as they ignored everything known about the energy-dependent RNA-mediated de novo creation of genes, see: The heat shock response is self-regulated at both the transcriptional and posttranscriptional levels (1982) Thirty-five years later, there is another clear indication that theorists and atheists will never consider the fact that there must be an anti-entropic virucidal source of energy. See for example: HSP90 Shapes the Consequences of…

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DNA repair via junk DNA (1)

Initiating DNA repair To communicate stress signals within cells, JNKs add phosphate groups to proteins, and the Rochester study found the amino acid residue on SIRT6 that is modified by JNK. They found an energy-dependent RNA-mediated amino acid substitution linked to the physiology of reproduction. It makes DNA repair and transgenerational epigentic inheritance of biologically-based cause and effect possible. The innate immune system, links RNA-mediated amino acid substitutions to supercoiled DNA and protection of organized genomes from virus-driven entropy. The…

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Neo-Darwinism vs the neocortex

From Fertilization to Adult Sexual Behavior Excerpt: (with my emphasis) Small intranuclear proteins also participate in generating alternative splicing techniques of pre-mRNA and, by this mechanism, contribute to c in at least two species, Drosophila melanogaster and Caenorhabditis elegans…. That similar proteins perform functions in humans suggests the possibility that some human sex differences may arise from alternative splicings of otherwise identical genes. Alternative splicing as a switch to enhance neuroprotection under stress Excerpt: Alternative splicing is an important post-transcriptional…

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Olfaction & the octopus and human genomes (2)

Darwinian evolution in the light of genomics Eugene Koonin excerpt: The distribution of evolutionary rates across sets of orthologous genes, the distribution of the sizes of paralogous gene families, the negative correlation between the expression level and the sequence evolution rate of a gene, and other relationships between key evolutionary and phenomic variables seem to be genuine universals of evolution. The simplicity of these universal regularities suggests that they are shaped by equally simple, fundamental evolutionary processes, rather than by…

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Viruses, amino acids, and somatic cell types

Although the ultimate origins of RNA viruses are uncertain, it seems reasonable to assume that these infectious agents have a long evolutionary history, appearing with, or perhaps before, the first cellular life-forms (38). The entire evolution of the microbial world and the virus world, and the interaction between microbes and viruses and other life forms have been left out of the Modern Synthesis… Perhaps the evolutionists have placed the cart before the horse on this issue, as proposed by several…

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An epigenetic trap (the prequel)

See also: An epigenetic trap (the sequel) Excerpt: “Support for the link from one epigenetic trap to cell type differentiation was included in the molecular epigenetics section of our 1996 review, which detailed how RNA-mediated chromatin remodeling occurs.” My comment: One epigenetic trap leads to the de novo creation of olfactory receptor genes and cell type differentiation. See also: Heterochromatin-mediated gene silencing facilitates the diversification of olfactory neurons. The first epigenetic trap links the sun’s biological energy to cell type…

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Are viruses microRNAs? (2)

The role of microRNAs in cell type differentiation can be compared in the context of the role of viruses and mutations that cause cancer. Facts provide a basis for explaining the biological basis of epigenetically-effected cell type differentiation in species from microbes to man. But first, those who are biologically uninformed must answer the question: Are viruses microRNAs? Andrew Jones aka anonymous_9001 is correct. Viruses are not microRNAs. anonymous_9001 5 / 5 (6) 11 hours ago Stupid question of the…

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Removing natural selection; reshaping the horse; adjusting evolutionary theory

Prehistoric genomes reveal the genetic foundation and cost of horse domestication Reported as: Reshaping the horse through millennia Excerpt: “Domestication is generally associated with repeated demographic crashes. Yet, mutations that negatively impact genes are not eliminated by selection and can even increase in frequency when populations are small. Domestication thus generally comes at a cost, as deleterious mutations can accumulate in the genome. This had already been shown for rice and dogs. Horses now provide another example of this phenomenon.” My…

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