brain development

Impeaching the God of Abraham (8)

2/22/21 In Case You Missed it. The cure for HIV and all other virus-driven pathology was announced today via an indexed publication found through my daily PubMed search for microRNA. Efficacy, accumulation, and transcriptional profile of anti-HIV shRNAs expressed from human U6, 7SK, and H1 promoters 12/31/20 & indexed on 2/22/21 announced “…a functional cure Impeaching the God of Abraham (8)

NIH’s ignorance: From roots to shoots (1)

NIH funded research on psychotherapeutic drugs failed to consider facts about how the light-activated assembly of the microRNA-RNA-peptide nanocomplex linked microRNA biogenesis in plants from what people eat to the microRNA-mediated assembly of endogenous opioid peptides and brain development via the pheromone-controlled physiology of reproduction and viral latency in species from microbes to humans. I’ve NIH’s ignorance: From roots to shoots (1)

Energy-dependent purifying selection / autophagy (2)

See: Energy-dependent purifying selection / autophagy Thanks to Teresa Binstock for alerting me to this example, which was reported as: Shared epigenetic changes underlie different types of autism. Teresa wrote: “You might enjoy a glance at a use of epigenetic technology. Findings begin to answer, why such syndrome-defining traits given such diverse inter-individual genetics and Energy-dependent purifying selection / autophagy (2)

Energy-dependent purifying selection / autophagy (5)

See: Energy-dependent purifying selection / autophagy (4) See also: Team develops method to better identify genes involved in diseases If we can pinpoint the genetic mutations that cause a particular disease, we can associate those mutations with specific proteins, and then design drugs to block or activate those proteins. We can also measure the activity Energy-dependent purifying selection / autophagy (5)

RNA-mediated theory killers (4)

DNA methylation and microRNA biomarkers for noninvasive detection of gastric and colorectal cancer Excerpt: At this moment, DNA methylation and non-coding RNA including with microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) represent the largest body of available literature on epigenetic biomarkers with the highest potential for cancer diagnosis. My comment: The SLC19A3 microRNA was mentioned RNA-mediated theory killers (4)

Nutrient-dependent trophic analogs

Adaptive Resistance in Bacteria Requires Epigenetic Inheritance, Genetic Noise, and Cost of Efflux Pumps Excerpt: Our results identify the molecular mechanism of epigenetic inheritance as the main target for therapeutic treatments against the emergence of adaptive resistance. Finally, our theoretical framework unifies known and newly identified determinants… Conclusion: Our model provides an explanation for the Nutrient-dependent trophic analogs

Protein isoforms do not evolve

This Is My Vision Of “Life” A Conversation With Richard Dawkins [4.30.15] Introduction by: John Brockman Excerpt: Through the amazing set of posttranscriptional mRNA processing mechanisms uncovered in the last 40 years (including alternative splicing and RNA editing), transcription of a single gene often results in the production of many distinct protein isoforms with very Protein isoforms do not evolve