brain

From quantum physics to quantum souls (4)

The long-range consequences of food energy-dependent social factors predictably link everything known about social odors called pheromones from the quantized energy in food to metabolism and biophysically constrained viral latency.  Sympatric speciation exemplifies what is known about how quantized energy links the pheromone-controlled physiology of reproduction to biophysically constrained viral latency in species from microbes to humans. In this review of biophysically constrained viral latency and biodiversity, I linked energy-dependent changes from angstroms to ecosystems in the mouse-to-human model of microRNA-mediated amino…

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A Mathematical Model Links Quantum Physics to Quantum Souls (1)

Historical facts: All energy-dependent cell type differentiation is biophysically constrained by the de novo creation of microRNAs and enzymes that metabolize food and drugs. All food energy-dependent metabolism occurs in the context of microRNA-mediated cause and effect and the physiology of pheromone-controlled reproduction. The food energy-dependent pheromone controlled physiology of reproduction in bacteria links what organisms eat to the transgenerational epigenetic inheritance of their morphological and behavioral phenotypes. The virus-driven degradation of messenger RNA has been linked to all pathology…

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Energy-dependent physical and biophysical constraints (7)

See first: Energy-dependent physical and biophysical constraints (6) Stems Cells in the Hypothalamus Slow Aging in Mice My comment to The Scientist Cai says microRNAs could be a potential mechanism by which hypothalamic neural stem cells have such wide-ranging effects on aging, yet he believes that neurogenesis may also be involved. See also: Feedback loops link odor and pheromone signaling with reproduction At least 10,000 neurons in 26 different brain areas appear to transmit signals directly to GnRH neurons.  GnRH…

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Light, behavior and autophagy, a gender-specific risk factor

Structure of photosystem II and substrate binding at room temperature Excerpt: PS II, a membrane-bound multi-subunit pigment protein complex, couples the one-electron photochemistry at the reaction centre with the four-electron redox chemistry of water oxidation at the Mn4CaO5 cluster in the oxygen-evolving complex (OEC). New, detailed snapshots capture photosynthesis at room temperature The living machinery responsible for photosynthesis – while commonplace and essential to life on Earth – is still not fully understood. It is understood at every level of…

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Models of scientific literacy

Scientific Literacy Redefined Researchers could become better at engaging in public discourse by more fully considering the social and cultural contexts of their work. By Cynthia Brandenburg | February 1, 2016 Excerpt: …any truly productive conversation about why their fears are scientifically unfounded must be predicated upon an understanding of what caused those fears in the first place. My comment: “A Fear of Pheromones” led many researchers to ignore the fact that metabolic networks must be linked to genetic networks…

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Cytogenetic approaches link biosystems to ecosystems

Cytogenetic approaches for determining ecological stress in aquatic and terrestrial biosystems (Original Russian Text E.V. Daev, A.V. Dukelskaya, L.V. Barabanova, 2014, published in Ecologicheskaya Genetika, 2014, Vol. 12, No. 2, pp. 3–12.) For comparison see this open access review: Assessing vertebrate biodiversity in a kelp forest ecosystem using environmental DNA The Russian group seemed to me to be ~20 years ahead of the US-based research group. Eugene Daev explained the differences in the approach taken in the two published works.…

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RNA-mediated theory killers (11) (12) (13) (14) (15)

Historical perspective Scent of a Book Deal (1995) Excerpt: The search for love the second time around can sometimes lead to scientific as well as romantic inspiration. At least, that’s what happened to James Vaughn Kohl, coauthor of the recently published volume The Scent of Eros (New York, Continuum Publishing Co., 1995). In a press release accompanying the book, Kohl-who manages a clinical laboratory for a group of physicians at Partell Medical Center in Las Vegas-writes, “My scientific interest in…

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Mystery machine vs model

See: Mystery machine vs medical intelligence Is nutrition the future of brain health? Excerpt: Steindler’s focus on the link between nutrition and neurodegenerative diseases is unique in the field. My comment: If he has limited his claims to those associated only with neurodegenerative diseases, his focus is too narrow. Unfortunately, narrow focus is common among specialists. Their focus makes them specialists, and without them generalists could not connect the specialties to healthy longevity and/or pathology. Not just brain health or…

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RNA-mediated cell type differentiation: Honeybee

Changes in the Gene Expression Profiles of the Hypopharyngeal Gland of Worker Honeybees in Association with Worker Behavior and Hormonal Factors Excerpt: …amino acid spacer connecting the Zn-finger motifs [49], is an early JH-response gene that mediates JH action downstream of Met [46]. My comment: RNA-mediated amino acid substitutions link the epigenetic landscape to the physical landscape of DNA via the nutrient-dependent physiology of reproduction and cell type differentiation in all genera. — see Nutrient-dependent/pheromone-controlled adaptive evolution: a model. Excerpt:…

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A lighting requirement for life

Some Principles of Causal Analysis in Genetics (1936) Extract: high frequency radiation and particles of high velocity are very important components of the environment, causing heritable changes by a process called mutation. Even if we could conduct our experiments behind 30 metres of lead the fact that mutation has a temperature coefficient is enough to show that it depends in part on energy fluctuations which are uncontrollable. Mutations must be controlled. See also: Life on Earth – Flow of Energy…

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