Epigenetic switch links MicroRNAs to RNA-protein interactions
N6-methyladenosine marks primary microRNAs for processing Excerpt: “Our findings reveal that the m6A mark acts as a key post-transcriptional modification that promotes the initiation of miRNA biogenesis.” Reported as: Chemical tag marks future microRNAs for processing, study shows Excerpt: “… these experiments have identified a switch that can be used to ramp up or tamp down microRNA levels, and as a result, alter gene expression” My comment: The ‘m6A-switch’ aka the ‘m6A mark’ appears to link ecological variation to nutrient-dependent…