chemotaxis

Energy-dependent cellular communication

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Communication shapes sensory response in multicellular networks Significance Cells routinely sense and respond to their environment, and they also communicate with each other. Exactly how communication impacts sensing remains poorly understood. We study a population of fibroblast cells that responds to a chemical stimulus (ATP) and communicates by molecule exchange. Combining experiments and mathematical modeling, … Energy-dependent cellular communication

Non-random pheromone-controlled cell type differentiation

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Experience-Dependent Plasticity Drives Individual Differences in Pheromone-Sensing Neurons Aug 17, 2016   •Individual differences in cell types are not random •Sex differences in pheromone-sensing neurons are controlled by experience •Changes in specific cell types are governed via “use it and lose it” plasticity •Targeting plasticity to specific cell types changes animal behavior This was reported … Non-random pheromone-controlled cell type differentiation

RNA methylation (2)

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Conditioning as an adjunct in the pharmacotherapy of lupus erythematosus Several studies have provided evidence suggesting that “placebo effects” represent conditioning phenomena and that learning processes influence the response to placebo medication. This case report describes an adolescent with severe lupus erythematosus who received cyclophosphamide (CY) paired with taste (cod liver oil) and smell (rose … RNA methylation (2)

Model vs theory: Progress report!

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On June 14, 2013, 1) Nutrient-dependent/pheromone-controlled adaptive evolution: a model and 2) Mutation-Driven Evolution were published with divergent/opposite conclusions. 1) …the largest contributor to the development of our personal preferences may be the unconscious epigenetic effects of food odors and pheromones on hormones that organize and activate behavior. If so, the model represented here is … Model vs theory: Progress report!

MicroRNAs and/or QTLs: Who buried what?

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Making precision medicine a reality: Genomics researchers unveil road map to disease origin Excerpt: This study highlights the significance of mechanistic similarities for uncovering additional interacting downstream effectors of intergenic SNPs… My comment: Use of the term QTL may limit the understanding of how energy-dependent cell type differentiation occurs and how virus-driven energy theft is … MicroRNAs and/or QTLs: Who buried what?

Molecular Diagnostics: What is unprotected life?

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Facile Recoding of Selenocysteine in Nature Abstract excerpt: This illustrates the ease by which the genetic code may evolve new coding schemes, possibly aiding organisms to adapt to changing environments, and show the genetic code is much more flexible than previously thought. My comment: It also refutes the ridiculous theories of neo-Darwinists, by placing ecological … Molecular Diagnostics: What is unprotected life?

Confusing effects and affects of visual input

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Their report indicates that these researchers never learned to differentiate between epigenetic effects on RNA-mediated cell type differentiation compared to the experience-dependent affects on behavior of amino acid substitutions. Experience Affects Critical Period Plasticity in the Visual Cortex through an Epigenetic Regulation of Histone Post-Translational Modifications Excerpt: We show that the early exposure of rat … Confusing effects and affects of visual input

Selective reporting of inferences: examples of pseudoscience

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In the narrative of this presentation on RNA mediated molecular epigenetics and virus driven entropy, I mentioned that Cori Bargmann is scheduled to deliver a lecture entitled “Genes, neurons, circuits and behavior: an integrated approach in a compact brain.” An integrated approach will help others understand what is currently known about how ecological variation leads … Selective reporting of inferences: examples of pseudoscience