chromatin remodeling

microRNA-mediated quantum error correction (4)

I’ve posted presentation abstract submissions here because I anticipated they would not be selected for presentation. See: UV light, H2O, and epigenetic effects… (1) 9/25/20 Submitted by James V. Kohl on 9/25/20 for presentation during the Epigenetics – From Bench to Clinic session: RNA modifications and epitranscriptomics​​ Moderator Tony Kouzarides Conclusion: Theorists who ignore the microRNA-mediated quantum error correction (4)

Light-activated PTEN-dependent viral latency (1)

See: Dependence of RNA synthesis in isolated thymus nuclei on glycolysis, oxidative carbohydrate catabolism and a type of “oxidative phosphorylation” (1964) The synthesis of RNA in isolated thymus nuclei is ATP dependent. The energy required for biophysically constrained oxidative phosphorylation, viral latency, and cell type differentiation comes from food. Amusing anecdote (for polymaths): See: PTEN Light-activated PTEN-dependent viral latency (1)

Pattern recognition vs evolutionary processes (revisited)

Summary: Recent findings suggest that polyphenols display the ability to reverse adverse epigenetic regulation involved in pathological conditions, such as obesity, metabolic disorder, cardiovascular and neurodegenerative diseases, and various forms of cancer. That suggests the ignorance of pseudoscientists who fail to link pattern recognition from the food that organisms eat to the pheromone-controlled physiology of Pattern recognition vs evolutionary processes (revisited)

Epigenetically-effected nucleosome repositioning sheds Dobzhansky’s light on evolution

Crystal structure of the overlapping dinucleosome composed of hexasome and octasome My summary: Nucleosomes are dynamic entities that are repositioned by energy-dependent links from sunlight to ATP and RNA biosynthesis that act on DNA during the chromatin remodeling, which is biophysically constrained by the pheromone-controlled physiology of reproduction during the transgenerational epigenetic inheritance of all Epigenetically-effected nucleosome repositioning sheds Dobzhansky’s light on evolution

Energy-dependent chirality (2)

See Energy-dependent chirality 2013 MicroRNA-based regulation of epithelial–hybrid–mesenchymal fate determination See also E. Ben-Jacob Ben-Jacob et al., have linked everything currently known about natural information processing from natural selection for energy-dependent codon optimality to healthy longevity and from virus-driven energy theft to mutations that cause cancer. See for comparison: LH Tsai Tsai laboratory Our primary Energy-dependent chirality (2)

De novo gene creation: Ignoring the experimental evidence

Regularly Whiffing Essential Oils Can Retrain Lost Sense of Smell It’s not entirely clear how olfactory training works on a neurological level. Olfactory training links the experience-dependent de novo creation of G protein-coupled receptors to supercoiled DNA. Conserved molecular mechanisms link food odors and pheromones from the innate immune system to the physiology of reproduction. De novo gene creation: Ignoring the experimental evidence

Energy-dependent polycombic ecological adaptation

Are Humans Evolving Now Excerpt: This post will discuss current genetic data on what current evolution seems to be taking place. My comment: It is time for all science bloggers and journalists to stop making claims about evolution. None of their claims have ever been supported by experimental evidence of biologically-based energy-dependent top-down causation and Energy-dependent polycombic ecological adaptation

Did evolution autophosphorylate your kinases? (3)

Did evolution autophosphorylate your kinases? (1) Did evolution autophosphorylate your kinases? (2) See also: N6-Methyladenosine in Flaviviridae Viral RNA Genomes Regulates Infection Reported as: Chemical tags affect ability of RNA viruses to infect cells Dynamics of Human and Viral RNA Methylation during Zika Virus Infection Reported as:  Zika virus infection alters human and viral RNA Did evolution autophosphorylate your kinases? (3)

Nutrient-dependent pheromone-controlled autophagy (2)

See also: Nutrient-dependent pheromone-controlled autophagy Autophagy: cellular and molecular mechanisms (2010) Conclusion: … autophagy has emerged as a new and potent modulator of disease progression that is both scientifically intriguing and clinically relevant. My comment: Autophagy is energy-dependent and linked to supercoiled DNA by epigenetic effects on the innate immune system, which are linked to the Nutrient-dependent pheromone-controlled autophagy (2)

Nutrient-dependent pheromone-controlled autophagy

See also: Nutrient-dependent pheromone-controlled autophagy (2) The Excitable Mitochondria links 4 neurons from a nutrient energy-dependent pheromone-controlled network in a marine invertebrate to human brain development via the conserved molecular mechanisms that link the speed of light on contact with water to the de novo creation of G protein-coupled receptors (GPCRs).  Receptor-mediated species -specific chromatin Nutrient-dependent pheromone-controlled autophagy