Codon optimality

Pheromones protect us from viruses (10)

Twitter Profile: MicroRNA.pro, http://Autophagy.pro & http://RNA-mediated.com link subatomic particles from pH-dependent peptide synthesis to sympatric speciation and healthy ecosystems. Before 4/6/21, I had contributed 40,000 tweets @microRNApro to support claims about how light-activated carbon fixation is linked to healthy longevity in more than 118,400 indexed publications that mention ‘microRNA.’ For a historical perspective on the development of healthy ecosystems, see: Pheromonal Regulation of Genetic Processes: Research on the House Mouse (Mus musculus L.) (1994) “The specificity of pheromonal regulation depends…

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Defeating disease and Communism (3)

More than 117,000 published works that mention ‘microRNA‘ can be linked from: Playing games with quantum interference 3/10/21 via MicroRNAs organize intrinsic variation into stem cell states 3/5/20 and MicroRNA Involvement in Signaling Pathways During Viral Infection 3/10/20 to the game for ages 14+ Genotype. Everything known to intelligent serious scientists has been linked to Thomas Hunt Morgan’s claims about chromosomal rearrangements and sympatric speciation in flies and other insects. See also: Hypoxia associated multi-omics molecular landscape of tumor tissue…

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Impeaching the God of Abraham (6)

I repeat: “The epigenetic effects of olfactory/pheromonal input calibrate and standardize molecular mechanisms for genetically predisposed receptor-mediated changes in intracellular signaling and stochastic gene expression…” Catalytic Asymmetric Synthesis of the anti‐COVID‐19 Drug Remdesivir 9/1/20 The catalytic asymmetric synthesis of the anti-COVID-19 drug Remdesivir… showed that this DyKAT is a first-order visual kinetic reaction dependent on the catalyst concentration. The unique chiral bicyclic imidazole skeleton and carbamate substituent of the catalyst are both required for the racemization process… The racemization process…

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Impeaching the God of Abraham (1)

2/10/21 Researchers who share the Abrahamic faiths have refuted the pseudoscientific nonsense touted by all atheists. See: microRNA 115, 376 results There are currently 1052 results for microRNA and Israel 2,063 results for microRNA and Iran 2414 results for microRNA and Korea For a historical perspective on what is known to all intelligent serious scientists about biophysically constrained viral latency across kingdoms see the references from: Regulation of host and virus genes by neuronal miR-138 favours herpes simplex virus 1…

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A single base change refutes theistic evolution

Everyone who failed to learn how light-activated endogenous substrates biophysically constrain viral latency is playing “catch up” to serious scientists. The serious scientists know how quantized energy-dependent RNA-mediated cell type differentiation occurs in the context of the physiology of reproduction in all living genera. Rather than accept the fact that the innate immune system of bacteria (CRISPR) linked the pheromone-controlled physiology of reproduction from autophagy to biophysically constrained viral latency, theorists decided to waste money on virus-assisted gene-editing attempts to…

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Environmental selection is natural selection

Environmental selection during the last ice age on the mother-to-infant transmission of vitamin D and fatty acids through breast milk was published on April 23, 2018 The ectodysplasin A receptor (EDAR) gene has a range of pleiotropic effects, including sweat gland density, incisor shoveling, and mammary gland ductal branching. The frequency of the human-specific EDAR V370A allele appears to be uniquely elevated in North and East Asian and New World populations due to a bout of positive selection likely to…

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The eternal significance of microRNAs (4)

Conclusion: Conserved energy biophysically constrains viral latency. Metatranscriptomics High-throughput sequencing and analysis of microbial community cDNA are providing valuable insight into in situ microbial activity and metabolism in the oceans. When faced with the eternal significance of quantized energy-dependent natural selection for codon optimality, theorists must attack the basics of what is known to serious scientists about biophysically constrained life on Earth. See for example: Virus-mediated archaeal hecatomb in the deep seafloor By starting with “raw assemblies” instead of the…

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From photons to the proton motive force (2)

If you know someone who has linked differences in the energy of photons from the proton motive force to the physiology of reproduction and all biophysically constrained biodiversity, ask if they will attend Schrödinger at 75-The Future of Biology For contrast, touting genetic evolution is not the future of biology. See: Abstract: K06.00013 : A Path Integral Method for Analytically Tractable Inference of Evolutionary Dynamics Understanding the forces that shape genetic evolution is a subject of fundamental importance in biology…

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Diet-driven RNA interference and cancer prevention (3)

Excerpt: They claim to have found novel autoregulatory feedback loops that link changes in microRNAs to the alternative splicing factors SRSF1 and SRSF2.  Ectopic expression of SRSF1 can automagically repress the level of multiple microRNAs and SRSF2 can automagically upregulate miRNA expression. The fact that a peer-reviewed work published in 2018 links autoregulatory feedback loops to automagically altered gene expression and apoptosis via alternative splicings of pre-mRNAs suggests it is time for all serious scientists to retire. The magic of pseudoscientists has…

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For God and Country

Kinetically Stable Thermodynamically Activated Cell Metabolism (2)

Conclusion: The link from food to pheromones requires a link from the energy-dependent creation of enzymes to the functional structure of supercoiled DNA. See:  Evolution’s Achilles’ Heels” (DVD) …fifteen Ph.D. scientists collaborated to produce a coordinated, coherent, powerful argument. All of the contributors received their doctorates from similar secular universities as their evolutionary counterparts. Each is a specialist in a field relevant to the subject: Natural selection, origin of life, geology, genetics, radiometric dating, the fossil record, cosmology, and ethics.…

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