D-serine

Death cures theorist’s Amyotrophic Lateral Sclerosis (ALS).

Stephen Hawking death: Was he the smartest man in the world? The media need superheroes in science just as in every sphere of life, but there is really a continuous range of abilities with no clear dividing line. For comparison: Focus on the Role of D-serine and D-amino Acid Oxidase in Amyotrophic Lateral Sclerosis/Motor Neuron Disease (ALS) A pathogenic mutation in D-amino acid oxidase (DAO) associated with familial ALS impairs D-serine metabolism and causes protein aggregation, autophagy and cell death…

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A single amino acid substitution differentiates cell types of E. coli

Rare amino acid influences E. coli infection Excerpt: “They found that E. coli O157 is unable to attach itself to host tissue in high concentrations of D-Serine. Other strains, such as those that cause meningitis, thrive in the presence of the amino-acid.” My comment: Three steps are required to link the amino acid substitution in E. coli to RNA-mediated stability of the DNA in the organized genome of a nutrient-dependent strain. 1) nutrient-dependent potentiation makes a trait possible; 2) receptor-mediated…

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