de novo

Less evolvable RNA-mediated ecological adaptations

No experimental evidence of biophysically constrained RNA-mediated cell type differentiation supports the claim about “…the evolutionary plasticity of the regulatory regions involved in transcriptional regulation…” The overwhelming systems complexity of energy-dependent RNA-mediated cause and effect can no longer be placed into the context of the pseudoscientific nonsense touted by theorists. Watch Andrea Wagner’s group try to escape from the claims made by losers. But first see: Kalevi Kull: Censorship & Royal Society Evo Event Nobody wants to belong to the…

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RNA-mediated nutritional psychiatry (2)

Codon identity regulates mRNA stability and translation efficiency during the maternal-to-zygotic transition The amino acid optimality code (Fig 6) provides an alternative perspective on sequence changes between paralogs in evolution and human disease. Neo-Darwinian theorists dispense with Darwin’s food energy-dependent  “conditions of life.” They link mutations and disease to evolution via mathematical models. They exemplify human idiocy. See for example: Neopterygian phylogeny: the merger assay Reported as: Adaptive radiations in the Mesozoic Bony fishes are the most diverse of all…

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RNA-mediated nutritional psychiatry

Summary: Young Genes are Highly Disordered as Predicted by the Preadaptation Hypothesis of De Novo Gene Birth Stop this nonsense about de novo gene birth and you will help to stop the school shootings without more gun control. See my presentation at the 2017 Precision Medicine Virtual Conference (2/15/17) Energy as information and constrained endogenous RNA interference See also: Pat Sweeney et al (3/13/2017) Protein misfolding in neurodegenerative diseases: implications and strategies.  A notable development is the creation of collaborative…

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Exposing the 2nd Law to more ridicule (1)

Summary: Experiment demonstrates quantum mechanical effects from biological system Schrödinger (1944) linked the anti-entropic virucidal energy of sunlight from the physiology of pheromone-controlled reproduction in soil bacteria to all biodiversity. He then began to suspect that his colleagues, who displayed human idiocy, would kill him – if ever again he reasserted the facts. After 1944, Richard P. Feynman took a stand against the human idiocy, and lost. He was not killed, just ignored. Ignorance prevails. It always has. The virus-driven…

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DNA repair via junk DNA (2)

See also: DNA repair via junk DNA (1) Recently Evolved Genes Identified From Drosophila yakuba and D. erecta Accessory Gland Expressed Sequence Tags (2006) Reported in Singer (2015) as: In 2006, Begun found some of the first evidence that genes could indeed pop into existence from noncoding DNA. Singer’s claim that genes automagically pop into existence is consistent with Masatoshi Nei’s conclusion in: Mutation-Driven Evolution …genomic conservation and constraint-breaking mutation is the ultimate source of all biological innovations and the…

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Masters of deception about nature (2)

See my other blog posts on RNA methylation Thanks for your review of How Can Physics Underlie the Mind?: Top-Down Causation in the Human Context (The Frontiers Collection) Others linked the sun’s anti-entropic virucidal energy from energy-dependent changes in hydrogen-atom transfer in DNA base pairs in solution to supercoiled DNA, which protects all organized genomes from virus-driven energy theft and genomic entropy. Ellis comments on at least one of Schrodinger’s claims from “What is Life?” but he largely ignores the…

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War Games: False Flag Terrorism

Sirius Cyantis (aka Sean Ovis) takes my claims about virus-driven energy theft and pathology outside the context of creationism.  Using his assumed name, he places them into the context of support for evolution. That’s an example of what happens on the “False Flag” Creationism FB group. In the context of combating evolution to fight disease, the war games become more interesting. Most people in False Flag groups do not know who they are fighting against. In the end it won’t…

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Gene creation (revisited)

New genes from non-coding sequence: the role of de novo protein-coding genes in eukaryotic evolutionary innovation Abstract: The origin of novel protein-coding genes de novo was once considered so improbable as to be impossible. In less than a decade, and especially in the last five years, this view has been overturned by extensive evidence from diverse eukaryotic lineages. There is now evidence that this mechanism has contributed a significant number of genes to genomes of organisms as diverse as Saccharomyces,…

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Creating genes and species

The Octopus Genome: Not “Alien” but Still a Big Problem for Darwinism by Casey Luskin, August 24, 2015 Excerpt: Whenever you see “de novo” origin of a gene invoked, you know that evolutionary biologists lack any explanation for how that gene arose. My comment: I tend to use the experience-dependent “de novo” creation of olfactory receptor genes as an example of how RNA-mediated events link physics, chemistry, and biology from atoms to ecosystems via the conserved molecular mechanisms of biophysically…

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Ecological adaptations reported as evolution in insects and mammals

Evolution of mosquito preference for humans linked to an odorant receptor Excerpt: “Our results also provide insight into the molecular basis of behavioural evolution.” See their diagram in Extended Data Figure 3: Amino acid differences of major Or4 protein alleles. Excerpt: Dots represent amino acid differences with respect to the genome reference, not an inferred ancestor. Reported as: Study suggests how mosquitoes evolved an attraction to human scent Excerpt: The switch from preferring animals to humans involves a variety of…

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