degradation of messenger RNA

Plenty of Room at the Bottom

Cryo-EM: Linking spatial and conformational constraints

On Darwin Day (2018) Carl Zimmer suggested use of the twitter hashtag #Istudyevolution to report whatever aspect of biology people were studying. For example, Richard Lenski reported that he studied adaptation in E. coli. When I told others that ecological adaptation is nutrient-dependent and pheromone-controlled in species from microbes to humans, he blocked me from seeing his comments. Evidently he did not want people to know that he had been studying ecological adaptation for more than 2 decades but reporting…

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From base editing to RNA editing (8)

Excerpt: See: Quantum Vacuum Dynamics, Coherence, Superluminal Photons and Hypercomputation in Brain Microtubules Finally, these theorists attempt to link the speed of light on contact with water (Darwin’s “conditions of life”) to all biophysically constrained biodiversity. Researchers find potential path to repair multiple sclerosis-damaged nerves December 26, 2017 Multiple sclerosis is an autoimmune, neurodegenerative disease, characterized by distinct disabilities affecting walking, vision, and cognition, to name a few. MS patients differ markedly from each other regarding which disability affects them…

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For God and Country

Faith in evolution: Paleontology as a molecular science

Keeping the faith For the last 20 years, Mary Schweitzer, a paleontologist at North Carolina State University in Raleigh, has amassed a wealth of evidence that she’s isolated protein fragments from dinosaurs as much as 80 million years old. That bucks the conventional wisdom among paleontologists who argue that proteins, which are made of chains of amino acids, can’t survive more than 1 million years or so. So far, no group other than Schweitzer and her collaborators has managed to…

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Lethal virus kills 5 billion people?

Until death: Virus-driven failure of multisensory integration (2)

Summary: The virus-driven degradation of messenger RNA is clearly linked to frontotemporal dementia (FTD) by altered language, personality, behavior, cognition and motor function. What causes FTD? If the virus-driven degradation of messenger RNA causes all pathology, I would expect to find a link from microRNAs to the pathology and to the effective treatment. The social and economic burden of frontotemporal degeneration Reported as: Study reveals staggering economic burden of dementia in younger people Frontotemporal degeneration (FTD) accounts for 20 to…

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Thanks again for asking about DNA methylation

Re: RNA-directed DNA methylation (1996) See: From Fertilization to Adult Sexual Behavior Molecular epigenetics. It is now understood that certain genes undergo a process called “genomic or parental imprinting.” Early in embryonic development attached methyl groups become removed from most genes. Several days later, methyl groups are reattached in appropriate sites. Fascinatingly, some such genes reestablish methylation patterns based upon whether the chromosomal segment carrying the gene came from maternal or paternal chromosomes. See also: RNA-directed DNA methylation: an epigenetic…

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For God and Country

Dispelling the ignorance of theorists

American Legion Riders (Riding for God and Country on 9/9/17) Summary: The highest-order of energy-dependent pre-assembly of respiratory chain complexes allows mitochondria to respond to energy-requiring conditions. There is no such thing as the emergence of energy, self-assembly, self-organization or any other pseudoscientific nonsense touted by theorists. Their theories exemplify what Richard P. Feynman referred to as “human idiocy.” That is why I refer to theorists who argue with me as “biologically uninformed science idiots.” Friends sometimes tell me I…

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Energy and neural plasticity

Summary: Food energy is required because proteins do not create themselves and virus-driven energy theft causes the degradation of messenger RNA in all living genera. See for comparison: Neural plasticity wanes with age, but increasing the protein Arc—abundant earlier in life—in the visual cortex of mice can fend off this decline. The restoration of neural plasticity requires the food energy-dependent pheromone-controlled de novo creation of genes. For example, see: Natural Selection on the Olfactory Receptor Gene Family in Humans and Chimpanzees Desperate…

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Your indifference is killing you and others (2)

Two family members and two close friends are among those who have unfriended me on Facebook. Like the late Carl Woese and Eugene Koonin, they are not willing to examine any of the facts about energy-dependent RNA-mediated cell type differentiation. I have never asked anyone to do that until after they have claimed or inferred that my facts are wrong or that the facts do not prove anything. At that point, their indifference is what causes more unnecessary suffering and…

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Your indifference is killing you and others (4)

Summary: I suspect that Subatomic, like Cytosis, will help link atoms to ecosystems via my model of nutritional epigenetics and the pheromone-controlled visual perception of mass and energy, which has been linked from the sense of smell in bacteria across the space time continuum via olfaction. From 7 years ago. Published 7 years ago on 15 Aug 2010 by James V. Kohl of,, and Kohl is the co-author of “The Scent of Eros” and he is the…

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Energy-dependent physical and biophysical constraints (9)

Summary: Energy determines genome compaction because activity in the nucleus is energy-dependent. Chromatin chains link energy-dependent changes in base pairs from single nucleotide polymorphisms to fixation of RNA-mediated amino acid substitutions in organized genomes via the physiology of pheromone-controlled reproduction. It’s all about the base. Energy-dependent physical and biophysical constraints (8) ChromEMT: Visualizing 3D chromatin structure and compaction in interphase and mitotic cells Excerpt 1) The chromatin structure of DNA determines genome compaction and activity in the nucleus. My comment:…

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  • What Darwin proved: there’s no such thing as a species
    GENETICS As Animals Mingle, a Baffling Genetic Barrier A short stretch of DNA is challenging what it means to be a species. By: Emily Singer August 5, 2014 Excerpt: “Scientists have dubbed such regions of the genome “islands of speciation.” The persistence of such islands is a phenomenon that has been observed in a variety of […]
  • Randomness and Divine Providence
    A Q&A on randomness and God’s providence …the main goal is to really put together a collection of scholarly studies of these issues: physicists, biologists, […]
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