development

Ecological Adaptations vs the Randomness of Evolution (2)

Summary: See for comparison: Make ‘Em Resistant to Viruses In the new proposal — which Science says was released in advance of a meeting today — GP-write leaders say “ultrasafe” cells could be developed by making some 400,000 changes to the human genome. A Fast One–Step Digestion of DNA or RNA for Global Detection and Characterization of Nucleotide Modifications (link opens pdf) Product information: The Nucleoside Digestion Mix is an optimized mixture of enzymes that provides a convenient one-step method…

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Enzyme-constrained interethnic biodiversity (3)

Excerpt: Understanding a “correlational mechanism” is like understanding mutation-driven evolution. You have a mutation. You have evolution. Thus, you understand the simple-minded magic of the correlation. No energy-dependent molecular mechanisms are required. For comparison: Enzyme-constrained interethnic biodiversity is exemplified in Amish populations in the United States of America. Obviously, interethnic difference in genes matter. See: Low cancer incidence rates in Ohio Amish (2009) Why Don’t The Amish Get Cancer? (2016) See also: A null mutation in SERPINE1 protects against biological…

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Science vs Secularism: Molecular Mechanisms or Math?

Summary: An example from ancient knowledge of trigonometry links pattern recognition as the basis for the science of creationism, and pattern recognition also is the basis for molecular biology. What form of virus-driven pathology would you most like to see eliminated from future consideration by serious scientists who know how energy-dependent RNA-mediated cell type differentiation occurs? In any case, a PubMed search for microRNA and your disease of choice will be enlightening. See for example: microRNA + Alzheimer’s or microRNA…

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Hypothesis free pseudoscience vs facts (5)

See first: Hypothesis free pseudoscience vs facts (4) Re: There is literally nothing left of neo-Darwinian pseudoscientific nonsense, and yet pseudoscientists still make the same ridiculous claims. See for comparison:  Current Drug Design Studies for Hsp70 in Oncological Applications SBD [substrate binding domain] contains hydrophobic amino acid residues, and this hydrophobic cavity helps unfolded substrate proteins to fold their native structure. Thus, exposed part of the folded proteins may not interact with each other and cause aggregation [in the context…

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Energy-dependent RNA methylation (7)

“…viral latency is responsible for life-long pathogenesis and mortality risk…” – Lieberman (2016) My comment: Energy-dependent RNA-mediated amino acid substitutions are responsible for life-long healthy longevity and decreased mortality risk. See for comparison: How cancer was created by evolution Excerpt 1) But even though it is evolutionary processes that have made cancer such a problem, it is also evolutionary thinking that is now leading to pioneering treatments that could stack the odds against cancer and in favour of our health.…

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Virus-driven energy theft: definition?

The FB group antagonists at “Creationism” complain that I am the only one who uses the term “virus-driven energy theft.” They want a definition, and they demand that I tell them my religious beliefs. Young-earth creationist, or not? It’s one of the “False Flag” FB groups, where impersonators claim to be well-educated experts from different disciplines, who then tout their expertise when they attack creationists at every level including denigration of published works and personal denigration of people’s worth. The…

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The tipping point? 50, 000 publications

There’s 10 trillion microbes on you; the White House wants to figure them out Excerpt: …start research into the microbes that shape life on Earth — including those in plants, animals, water, soil and air — as part of an effort to fight disease… “The entire evolution of the microbial world and the virus world, and the interaction between microbes and viruses and other life forms have been left out of the Modern Synthesis…“– Eugene Koonin (May 7, 2015)  …

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Neuroscience Virtual Event vs AAAS Symposium

Neuroscience Virtual Event Abstract Submission Poster title: From hydrogen-atom transfer in DNA base pairs to ecosystems (March 16-17, 2016) Abstract: This atoms to ecosystems model of ecological adaptations links nutrient-dependent epigenetic effects on DNA base pairs in solution and RNA-mediated amino acid substitutions to chromosomal rearrangements via pheromone-controlled changes in the microRNA / messenger RNA balance. The nutrient-dependent pheromone-controlled changes are required for the thermodynamic regulation of intracellular signaling, which enables biophysically constrained nutrient-dependent & pH-dependent protein folding; experience-dependent receptor-mediated behaviors,…

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Cytogenetic approaches link biosystems to ecosystems

Cytogenetic approaches for determining ecological stress in aquatic and terrestrial biosystems (Original Russian Text E.V. Daev, A.V. Dukelskaya, L.V. Barabanova, 2014, published in Ecologicheskaya Genetika, 2014, Vol. 12, No. 2, pp. 3–12.) For comparison see this open access review: Assessing vertebrate biodiversity in a kelp forest ecosystem using environmental DNA The Russian group seemed to me to be ~20 years ahead of the US-based research group. Eugene Daev explained the differences in the approach taken in the two published works.…

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NORAD: air defense and defense against genomic entropy

NORAD may refer to: North American Aerospace Defense Command… that provides aerospace… defense for North America Norwegian Agency for Development Cooperation Noradrenaline, a hormone and a neurotransmitter with multiple biological roles My comment: The modern use of radar includes air-defense systems and ocean surveillance systems.  High tech radar systems are designed to use the systems complexity of signaling and sensing to extract useful information from levels of very high noise.  In the context of protection from virus-driven genomic entropy use…

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