developmental gene expression

Olfactory receptor pseudo-pseudogenes

Olfactory receptor pseudo-pseudogenes Abstract: Pseudogenes are generally considered to be non-functional DNA sequences that arise through nonsense or frame-shift mutations of protein-coding genes1. Although certain pseudogene-derived RNAs have regulatory roles2, and some pseudogene fragments are translated3, no clear functions for pseudogene-derived proteins are known. Olfactory receptor families contain many pseudogenes, which reflect low selection pressures Olfactory receptor pseudo-pseudogenes