“The gene, cell, tissue, organ, organ-system pathway is a neuroscientifically established link between sensory input and behavior. Marts and Resnick (2007) stress the importance of this pathway in the context of a systems biology approach to pharmacogenomics.” (Kohl, 2012) “Naftolin (1981) stressed its importance to the understanding of sex differences. This pathway is sensitive to Pharmacogenomics