differential expression

Expert 13 (1)

12 Experts Questioning the Coronavirus Panic 3/19/20 President Donald J. Trump is expert 13 in the context of the fact that differential expression of cell types requires biophysically constrained viral latency. That fact became perfectly clear with the experimental evidence presented in  SARS-CoV-2 RNA reverse-transcribed and integrated into the human genome 12/13/20 The researchers: …investigated Expert 13 (1)

Epigenetically-effected nucleosome repositioning sheds Dobzhansky’s light on evolution

Crystal structure of the overlapping dinucleosome composed of hexasome and octasome My summary: Nucleosomes are dynamic entities that are repositioned by energy-dependent links from sunlight to ATP and RNA biosynthesis that act on DNA during the chromatin remodeling, which is biophysically constrained by the pheromone-controlled physiology of reproduction during the transgenerational epigenetic inheritance of all Epigenetically-effected nucleosome repositioning sheds Dobzhansky’s light on evolution

Polycombic ecological adaptation as a science, not a theory (2)

Evolutionary Constraints in the β-Globin Cluster: The Signature of Purifying Selection at the δ-Globin (HBD) Locus and Its Role in Developmental Gene Regulation Conclusion: … the results here presented indicate that purifying selection is driving not only HBD evolution but also its neighbor pseudogene, HBBP1. In the light of recent advances in the characterization of Polycombic ecological adaptation as a science, not a theory (2)