differentiation

Models by evolutionary biologists are not models

How Networks Are Revolutionizing Scientific (and Maybe Human) Thought By John Edward Terrell, Termeh Shafie and Mark Golitko | December 12, 2014 | Excerpt: “…evolutionary biologists are now modeling series of complex networked relationships at multiple levels ranging from individual “letters” in the genome to protein-gene networks to interaction networks between organisms, thereby demonstrating that our genes are only our destinies to the extent that they link to each other and to the surrounding world—both social and natural.” My comment: That’s…

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The future of physics predicts no future for evolutionary theory

The ever-smaller future of physics ‘Theory of everything’ captures Weinberg’s imagination in Lee Historical Lecture Excerpt: “…there are hints that the answers to fundamental questions will reveal themselves at around a million billionths — between 10­-17 and 10-19 — of the radius of the typical atomic nucleus. My comment: Evolutionary theorists may not recognize the problem that this presents. By accepting de Vries definition of “mutation” and rejecting experimental evidence, which links the epigenetic landscape to the physical landscape of…

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Chemical ecology and RNA-mediated control of DNA loops

DNA Loop-the-Loops A new full-genome map indicates how DNA is folded within the nuclei of human cells.By Kate Yandell | December 11, 2014 Excerpt: “…many loops were conserved among cell types, and even between mice and humans. But others seemed to drive cell type-specific gene expression patterns.” My comment to The Scientist Magazine: Nutrient-dependent/pheromone-controlled adaptive evolution: a model. Excerpt: “A form of GnRH associated with sexual orientation in yeasts links control of the feedback loops and developmental processes required for…

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Atoms to ecosystems: Evolutionary theory vs the coelacanth

Biodiversity: Life ­– a status report “Species are disappearing quickly — but researchers are struggling to assess how bad the problem is.” I want to eliminate some of the researcher’s struggles, but a moderator at Nature has blocked all my comments for several months, perhaps permanently. I think my past comments on articles, like this one, explain why other comments are blocked. In the past, I commented each time I saw a misrepresentation of biologically-based cause and effect. The misrepresentations…

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Jumping back: Science or Pseudoscience? (2)

See: Jumping back: Science or Pseudoscience? European Science’s Great Leap Backward inferred that evolutionary theory is evidence-based science: Excerpt: “… the U.S. can claim no superiority in our approach to evidence-based science, as demonstrated by the fact that nearly half of the country rejects the “theory” of evolution…” This article attests to the need to substitute evidence-based science: Leading Activist Apologizes For Starting Anti-GMO Movement Excerpt: “But what about mixing genes between unrelated species? The fish and the tomato? Turns…

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Single-cell level assay of protein biosynthesis and degradation

High-throughput detection of miRNAs and gene-specific mRNA at the single-cell level by flow cytometry Excerpt: “We use this technique to show modulation of a microRNA critical for T-cell function, miR-155. We adapt this assay for simultaneous detection of mRNA and proteins by ImageStream technology.” Reported as: Technology breakthrough reveals cellular transcription process My comment: Their assay simultaneously detects epigenetically-effected changes in the miRNA/mRNA balance and proteins, which link nutrient-uptake to the physical landscape of DNA in the organized genomes of…

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Glycine and GnRH: Am I being pedantic?

Posted to the FB page on 12/3/14 at Skeptics; Atheists; Realists; Agnostics; Humanists Stephen Hawking and Brian Cox take part in Monty Python sketch – video Excerpt: “I think you are being pedantic.” My comment: Some people may think I am being pedantic. My focus is not on physics; it is on the role of GnRH in cell type differentiation. My focus now extends from what is known about quantum physics, quantum smell, chirality, quantum biology, and quantum consciousness. What is known about chirality…

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Extensive molecular evidence vs ridiculous theories

Mosquito Genomes Galore Whole-genome sequences of 16 different mosquito species reveal rapid evolution and could inform malaria research. By Ruth Williams | November 27, 2014 Excerpt: “…mosquitoes are rapidly evolving, exhibiting high degrees of gene gains, losses, shuffling, and even transmission between closely related species.” It is the reports on rapid evolution of insects that continues to limit the usefulness of any theories about mutations and or natural selection of anything except food. My comments (below) to The Scientist site…

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Meaningful dialogue, anonymous fools and idiot minions

I use definitions to describe differences in behavior. I do not define biologically-based facts in attempts to make the definitions fit into the context of ridiculous theories about the development of behavior. I am not an idiot. An idiot is “…someone who acts in a self-defeating or significantly counterproductive way…. An idiot differs from a fool (who is unwise)…. the terms “idiot” and “idiocy” describe an extreme folly or stupidity, and its symptoms (foolish or stupid utterance or deed).” Serious scientists may…

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Epigenetic pharmacology and RNA-mediated transciptional landscapes

Last year, Vosshall’s group eliminated ideas about the involvement of beneficial mutations in the nutrient-dependent cell type differentiation of mosquitoes. orco mutant mosquitoes lose strong preference for humans and are not repelled by volatile DEET. This year her group showed that nutrient-dependent amino acid substitutions clearly are involved in cell type differentiation. Evolution of mosquito preference for humans linked to an odorant receptor RNA-mediated events have since been linked to sexual dimorphism in mosquitoes. Examination of the genetic basis for sexual…

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