DNA methylation

Assumptions prove ignorance

Testing Einstein’s Equivalence Principle With Fast Radio Bursts Excerpt: Assuming as a lower limit that the time delays are caused mainly by the gravitational potential of the Milky Way, we prove that fast radio bursts (FRBs) of cosmological origin can be used to constrain the EEP with high accuracy. My comment: Theoretical physicists are allowed to start with assumptions and link them to theories via what they consider to be proof of their assumptions. Unfortunately, the proof of their assumptions…

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Did Dobzhansky see the UV light of creation?

Analemma. The sun’s position in the sky, photographed from the same location at the same time of day throughout a year, forms an analemma. This shows the sun’s apparent swinging from its northernmost position, at the analemma’s uppermost point, at summer solstice, to its southernmost position/lowest point, at winter solstice. My comment: Does this remind anyone else of a one-sided nonorientable surface obtained by cutting a closed band into a single strip with linked ends that can be used to…

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Researchers rename, reshuffle, and reveal their ignorance

New Species Abound Re: Researchers renamed, reshuffled, and revealed species… Evidently, NEW SPECIES is part of a misleading headline placed into the context of some that EMERGED. Adapted/updated from my comments on Beyond DNA See: A Cellular System for Spatial Signal Decoding in Chemical Gradients This cellular system links the sun’s anti-entropic force and the virucidal effect of UV light to the strategic cellular defense system of all cell types. Researchers began studying this particular molecule because the RNA kicks…

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RNA-mediated theory killers (4)

DNA methylation and microRNA biomarkers for noninvasive detection of gastric and colorectal cancer Excerpt: At this moment, DNA methylation and non-coding RNA including with microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) represent the largest body of available literature on epigenetic biomarkers with the highest potential for cancer diagnosis. My comment: The SLC19A3 microRNA was mentioned in the context of cancer and brain development in The impact of new technologies on clinical decision-making in health care. The location of the base…

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RNA-mediated theory killers (3)

  Ghosts in the Genome How one generation’s experience can affect the next By Oliver J. Rando | December 1, 2015 My comment: “…epigenetic information carriers include covalent modifications to nucleotides and histones, providing a wide variety of mechanisms that enable organisms to transmit information extragenomically.” When this was placed into its proper perspective, it was used in a parody by researchers who know how atoms and ecosystems are linked by RNA-mediated cell type differentiation in all living genera. See: …

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Life and death predicted by DNA methylation

The bounce rate here has more than doubled  (from 20% to 44%) during the past week at the same reports continue to support all the claims I have made about RNA-mediated cell type differentiation. Obviously, pseudoscientists are not willing to examine any evidence of biologically-based cause and effect that refutes their ridiculous claims about mutations and evolution. For comparison, serious scientists will want to read this: See: DNA methylation age is associated with mortality in a longitudinal Danish twin study…

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Theorists can’t understand biology

See also: Neuroplasticity Thanks to Teresa Binstock for calling my attention to this:   Thanks to Anna Di Cosmo for calling the attention of others to this: My comment: Attempts to explain the “binding problem” of integration in the context of ecoimmunology and disease ecology compared to emergence and evolution are examples of how much pseudoscientific nonsense has been accepted and touted in the context of the neo-Darwinian “Modern Synthesis.” For comparison, serious scientists have detailed a model of top-down…

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Receptor methylation controls behavior

The protein arginine methyltransferase PRMT5 promotes D2-like dopamine receptor signaling Excerpt 1) The addition of a methyl group to an arginine residue can remove a hydrogen bond donor and decrease the electrostatic surface potential at the residue, resulting in a change in size and hydrophobicity that can affect its interaction with binding partners (21). Excerpt 2) Together, these results led us to propose that arginine methylation promotes D2-like dopamine receptor signaling and that this mechanism of receptor regulation is conserved…

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From dust to genomic entropy?

Extreme eolian delivery of reactive iron to late Paleozoic icehouse seas Reported as: Dust, iron, life: How atmospheric dust prepped Earth for life Excerpt: The biogeochemical impacts of iron-rich dust to the oceans are known for Earth’s recent record but unexplored for deep time… My comment: The fact that this has been unexplored requires another untestable theory about dust-prepped Earth to explain the origin of what is happening in this video. My comment: The origins of how the dust-prepped Earth…

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Models are not theories (2)

MicroRNA-encoded behavior in Drosophila Editor’s summary: MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene activity. They repress expression through complementary base pairing interactions with target messenger RNAs. MiRNAs are involved in regulating many cell and developmental processes. Picao-Osorio et al. find that miRNAs can also control behavior in the fruit fly Drosophila. My comment: Ridiculous claims from 1) We are all mutants and from 2) Mutation-Driven Evolution can now be placed into the context of what is known to…

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