ecological adaptation

Quantum initiation of cold chemistry vs Hypeology (2)

June 21, 2018
James Kohl
Adaptations, Diseases & Disorders, Ecology, Light Energy, Model Organisms, RNA Directed
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See first: Quantum initiation of cold chemistry vs Hypeology (1) Genotype Genotype is a betting and manipulation game about cross-breeding pea plants, as in Gregor Mendel’s famous experiments. Players compete over three generations to predict the traits of new offspring, by controlling the parent plants’ genetic makeup (“genotype”). The offspring are determined by a die-roll at the end of each round and become the starting parents for the next generation. Changing the parent genotypes dramatically alters the likelihood of the…

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An evolutionary theory killer

Quantum initiation of cold chemistry vs Hypeology (1)

June 14, 2018
James Kohl
Adaptations, Alternative Splicings, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Physics, RNA Directed, RNA-mediated epigenetic regulation of gene expression, RNA–Mediated Epigenetic Heredity, Subatomic, Variations
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Cold chemistry with two atoms Summary For centuries, chemists have written equations representing chemical reactions by using symbols for atoms and molecules; for example, 2H2O + 2Na → 2NaOH + H2. This short notation shows only four reacting particles, but even in a classroom demonstration where a small piece of sodium is dropped in water, the total number of reactants will be on the order of Avogadro’s number (∼6 × 1023). On page 900 of this issue, Liu et al.…

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The eternal significance of microRNAs (5)

May 10, 2018
James Kohl
Adaptations, Autophagy, Cytosis, Diseases & Disorders, Ecology, RNA Directed, RNA–Mediated Epigenetic Heredity
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Excerpt: Researchers in South Korea, for example, have reminded the God-less Communist dictator of North Korea that one microRNA-mediated amino acid substitution in the influenza B virus could decimate the human populations that he thinks he rules. Conclusion: Conserved energy biophysically constrains viral latency. Ridiculously ignorant objections to my publication in what others claim is a predatory journal can be compared to my objection to publication of this article in PNAS. Environmental selection during the last ice age on the…

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Virus-mediated archaeal hecatomb in the deep seafloor

Carl Zimmer refutes theistic evolution (2)

March 11, 2018
James Kohl
Adaptations, Alternative Splicings, Diseases & Disorders, Ecology, RNA Directed, RNA–Mediated Epigenetic Heredity
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Carl Zimmer refutes theistic evolution (1) Carl Zimmer recognizes the need for a new definition of what heredity is. But he refuses to tell others what he knows about the role that viruses play in the transgenerational epigenetic inheritance of all pathology. Examples of inherited pathology typically include his misrepresentations among others who fail to link ecological variation to ecological adaptation in the context of energy-dependent biophysically constrained viral latency. See: Ancient Viruses Are Buried in Your DNA  by Carl…

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Ecological adaptation: A new definition of heredity (3)

March 9, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, Subatomic, What's in the News
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Excerpt: Moving forward: Novel and Haplotype Specific MicroRNAs Encoded by the Major Histocompatibility Complex …these data suggest that a subset of the identified novel miRNAs may contribute to the pathophysiology of numerous diseases, laying the groundwork for future studies to elucidate the functional connections of miRNAs to the numerous diseases associated with sequence variants within non-coding regions of the MHC. OMCD: OncoMir Cancer Database Dysregulation of miRNAs is commonly observed in cancers and it largely cancer dependent. The virus-driven theft…

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Ecological adaptation: A new definition of heredity (1)

March 6, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Diseases & Disorders, Ecology, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Variations
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Excerpt: ” …long-standing presumptions led to the claims made by biologically uninformed theorists who failed to link biophysically constrained viral latency to the recent origin of most protein-coding variants via the physiology of pheromone-controlled reproduction in species from microbes to humans…” She Has Her Mother’s Laugh: The Powers, Perversions, and Potential of Heredity May 29, 2018 | 672 Pages From the description of the book: 1) We need a new definition of what heredity is… 2) …Zimmer ultimately unpacks urgent…

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Creating biophysically constrained viral latency (2)

February 28, 2018
James Kohl
Adaptations, Diseases & Disorders, Ecology, Model Organisms, RNA Directed, RNA-directed DNA methylation
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Creating biophysically constrained viral latency (2) Serious scientists have reached the point where they are finally ready to expose the pseudoscientific nonsense during Evolution – Genetic Novelty/Genomic Variations by RNA Networks and Viruses and also during Schrödinger at 75 – The Future of Biology – September 2018. Until then, pseudoscientists may want to see these examples of accurate information about top-down causation. MicroRNA Processing Gene Methylation and Cancer Risk Methylation of three CpGs (DROSHA: cg23230564, TNRC6B: cg06751583, and TNRC6B: cg21034183) was prospectively…

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An evolutionary theory killer

Conceptual critique: Innateness vs the death gene (2)

February 14, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Subatomic, Variations
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Excerpt: Martie Haselton notes “…there’s a hidden adaptive intelligence that has been shaped over eons. Martie Haselton places that ecological adaptation into the context of the claim that “…our bodies are designed to fight off invaders, whether they take the form of a cold virus… (p 73.) and she mentions the link from the designer to one theory about menstruation: “female bleeding serves to flush out “bad” sperm that may carry bacteria, viruses and other pathogens.” (p. 84) See also:…

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Plenty of Room at the Bottom

Cryo-EM: Linking spatial and conformational constraints

February 13, 2018
James Kohl
Adaptations, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA interference, RNA-directed DNA methylation
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On Darwin Day (2018) Carl Zimmer suggested use of the twitter hashtag #Istudyevolution to report whatever aspect of biology people were studying. For example, Richard Lenski reported that he studied adaptation in E. coli. When I told others that ecological adaptation is nutrient-dependent and pheromone-controlled in species from microbes to humans, he blocked me from seeing his comments. Evidently he did not want people to know that he had been studying ecological adaptation for more than 2 decades but reporting…

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The MicroRNAome Strikes Back: A Sokalian hoax (6)

January 25, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, Diseases & Disorders, Ecology, RNA Directed
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The nature of nurture: Effects of parental genotypes Science  January 26, 2018 …nontransmitted alleles can affect a child through their impacts on the parents and other relatives, a phenomenon we call “genetic nurture.” It doesn’t matter what they call it, since there is no defined boundary between genetics and epigenetics. Reported as: You Are Shaped by the Genes You Inherit. And Maybe by Those You Don’t by Carl Zimmer January 25, 2018 A calf may inherit those milk-boosting variants from its mother. But…

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