ecological adaptation

Photonics in Forensics (8)

March 11, 2022
James Kohl
RNA Directed
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Light-activated carbon fixation, the resurrection of life in pear trees, and the resurrection of life in daffodils exemplifies how God’s pH-dependent peptide synthesis at the origin of life ~6000 years ago links microRNA-mediated  protein folding chemistry to protection of all organized genomes from the virus-driven degradation of messenger RNA (mRNA). For instance, see: Integrative global co-expression analysis identifies Key MicroRNA-target gene networks as key blood biomarkers for obesity 3/10/22 They linked God’s Creation of energy-dependent transcription factor networks to computational…

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Optoribogenetic-driven sympatric speciation (1)

September 30, 2020
James Kohl
Adaptations, Alternative Splicings, Diseases & Disorders, Ecology, Model Organisms, RNA Directed, RNA interference, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity
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For presentation during session: Polycomb and chromatin remodeling Historical perspective: Yet another kind of epigenetic imprinting occurs in species as diverse as yeast, Drosophila, mice, and humans and is based upon small DNA-binding proteins called “chromo domain” proteins, e.g., polycomb. These proteins affect chromatin structure, often in telomeric regions, and thereby affect transcription and silencing of various genes… Small intranuclear proteins also participate in generating alternative splicing techniques of pre-mRNA and, by this mechanism, contribute to sexual differentiation in at…

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pH-dependent viral latency (3)

May 25, 2020
James Kohl
Adaptations, Alternative Splicings, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, RNA Directed, RNA interference
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Most Memorial Day 2020 celebrations and services were cancelled due to the well-orchestrated coronavirus crisis, which led to restrictions on our Constitutional rights. During the past two years, I’ve linked the eternal significance of light-activated microRNA biogenesis to our Constitutional rights. See the 10-part series: The eternal significance of microRNAs (10) and the 10-part series: The microRNA-mediated future of humanity (10) See also: pH-dependent viral latency and pH-dependent viral latency (2) Ages 10-14+ can learn what is known about pH-dependent…

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Vaccines do not control pandemics (1)

May 15, 2020
James Kohl
Adaptations, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Model Organisms, Nutrigenomics, Pharmacogenomics, Physics, RNA interference, Subatomic
2 Comments

See: Emergence of Human G2P[4] Rotaviruses in the Post-vaccination Era in South Korea: Footprints of Multiple Interspecies Re-assortment Events 4/16/18 Compared to the G2 RotaTeq vaccine strain, 17-24 amino acid changes, specifically A87T, D96N, S213D, and S242N substitutions in G2 epitopes, were observed. Amino acid changes control pandemics. Congo: MSF Ebola vaccination begins 5/30/18 The Ebola vaccine (rVSVDG-ZEBOV-GP) is being used as part of the overall strategy to control the Ebola outbreak. There was no indication that the vaccine strategy…

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Quantum initiation of cold chemistry vs Hypeology (2)

June 21, 2018
James Kohl
Adaptations, Diseases & Disorders, Ecology, Light Energy, Model Organisms, RNA Directed
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See first: Quantum initiation of cold chemistry vs Hypeology (1) Genotype Genotype is a betting and manipulation game about cross-breeding pea plants, as in Gregor Mendel’s famous experiments. Players compete over three generations to predict the traits of new offspring, by controlling the parent plants’ genetic makeup (“genotype”). The offspring are determined by a die-roll at the end of each round and become the starting parents for the next generation. Changing the parent genotypes dramatically alters the likelihood of the…

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An evolutionary theory killer

Quantum initiation of cold chemistry vs Hypeology (1)

June 14, 2018
James Kohl
Adaptations, Alternative Splicings, base editing, biophotonics, Cytosis, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Physics, RNA Directed, RNA-mediated epigenetic regulation of gene expression, RNA–Mediated Epigenetic Heredity, Subatomic, Variations
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Cold chemistry with two atoms Summary For centuries, chemists have written equations representing chemical reactions by using symbols for atoms and molecules; for example, 2H2O + 2Na → 2NaOH + H2. This short notation shows only four reacting particles, but even in a classroom demonstration where a small piece of sodium is dropped in water, the total number of reactants will be on the order of Avogadro’s number (∼6 × 1023). On page 900 of this issue, Liu et al.…

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The eternal significance of microRNAs (5)

May 10, 2018
James Kohl
Adaptations, Autophagy, Cytosis, Diseases & Disorders, Ecology, RNA Directed, RNA–Mediated Epigenetic Heredity
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Excerpt: Researchers in South Korea, for example, have reminded the God-less Communist dictator of North Korea that one microRNA-mediated amino acid substitution in the influenza B virus could decimate the human populations that he thinks he rules. Conclusion: Conserved energy biophysically constrains viral latency. Ridiculously ignorant objections to my publication in what others claim is a predatory journal can be compared to my objection to publication of this article in PNAS. Environmental selection during the last ice age on the…

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Virus-mediated archaeal hecatomb in the deep seafloor

Carl Zimmer refutes theistic evolution (2)

March 11, 2018
James Kohl
Adaptations, Alternative Splicings, Diseases & Disorders, Ecology, RNA Directed, RNA–Mediated Epigenetic Heredity
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Carl Zimmer refutes theistic evolution (1) Carl Zimmer recognizes the need for a new definition of what heredity is. But he refuses to tell others what he knows about the role that viruses play in the transgenerational epigenetic inheritance of all pathology. Examples of inherited pathology typically include his misrepresentations among others who fail to link ecological variation to ecological adaptation in the context of energy-dependent biophysically constrained viral latency. See: Ancient Viruses Are Buried in Your DNA  by Carl…

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Ecological adaptation: A new definition of heredity (3)

March 9, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Diseases & Disorders, Ecology, Light Energy, microRNA editing, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, Subatomic, What's in the News
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Excerpt: Moving forward: Novel and Haplotype Specific MicroRNAs Encoded by the Major Histocompatibility Complex …these data suggest that a subset of the identified novel miRNAs may contribute to the pathophysiology of numerous diseases, laying the groundwork for future studies to elucidate the functional connections of miRNAs to the numerous diseases associated with sequence variants within non-coding regions of the MHC. OMCD: OncoMir Cancer Database Dysregulation of miRNAs is commonly observed in cancers and it largely cancer dependent. The virus-driven theft…

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Ecological adaptation: A new definition of heredity (1)

March 6, 2018
James Kohl
Adaptations, Alternative Splicings, Autophagy, base editing, biophotonics, Diseases & Disorders, Ecology, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA editing, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Variations
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Excerpt: ” …long-standing presumptions led to the claims made by biologically uninformed theorists who failed to link biophysically constrained viral latency to the recent origin of most protein-coding variants via the physiology of pheromone-controlled reproduction in species from microbes to humans…” She Has Her Mother’s Laugh: The Powers, Perversions, and Potential of Heredity May 29, 2018 | 672 Pages From the description of the book: 1) We need a new definition of what heredity is… 2) …Zimmer ultimately unpacks urgent…

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