ecological adaptation

The essence of precision medicine

March 8, 2017
James Kohl
Adaptations, Alternative Splicings, Diseases & Disorders, Ecology, Model Organisms, RNA Directed, RNA interference, RNA methylation, RNA-directed DNA methylation, Variations
One Comment

The media-industrial complex attack CNN chief: Politicians should oppose Trump’s attack on media …Trump’s labeling of the media as the enemy of the state was unfortunate and dangerous. It was an accurate label that has been supported by Bill Gates and the Allen Institute in the context of the forthcoming viral apocalypse. See for comparison this enemy of the state-issued media representation:   “We are all proud of professor Filipp’s accomplishments,” Vice Chancellor for Research Samuel Traina said. “He exemplifies…

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Theistic evolutionists fight back and lose (2)

February 27, 2017
James Kohl
Adaptations, Alternative Splicings, biophotonics, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Physics, RNA Directed, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Variations
2 Comments

For a historical perspective on the amount of ignorance theistic evolutionists and atheists have repeatedly displayed as they ignored everything known about the energy-dependent RNA-mediated de novo creation of genes, see: The heat shock response is self-regulated at both the transcriptional and posttranscriptional levels (1982) Thirty-five years later, there is another clear indication that theorists and atheists will never consider the fact that there must be an anti-entropic virucidal source of energy. See for example: HSP90 Shapes the Consequences of…

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Francis S. Collins refutes theistic evolution

February 15, 2017
James Kohl
Adaptations, Alternative Splicings, Autophagy, biophotonics, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations, What's in the News
3 Comments

Criticisms of the nutrient-dependent pheromone-controlled evolutionary model Based on his writings, both published and unpublished, James Kohl presents an unsupported challenge to modern evolutionary theory and misrepresentations of established scientific terms and others’ research. — Andrew Jones, BA Editor’s note The 2013 review article by James Vaughn Kohl published in Socioaffective Neuroscience & Psychology and criticized in the above Letter to the Editor was subjected to standard peer review and the revised version was accepted by me after it had…

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George Church refutes theistic evolution (3)

February 12, 2017
James Kohl
Adaptations, Alternative Splicings, Autophagy, biophotonics, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
One Comment

Fifty years of illumination about the natural levels of adaptation … George C. Williams developed in his 1966 book Adaptation and Natural Selection the essentials of a unifying theory of adaptation that remains robust today and has inspired immense progress in understanding how natural selection works. Light Could Propel Nanorobots on a “Fantastic Voyage” Through the Human Body “Light is a more effective option to communicate between the microscopic world and the macroscopic world,” said Tang. See also: George Church…

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Physicists: Desperate Acts (revisited)

February 6, 2017
James Kohl
Adaptations, Alternative Splicings, Autophagy, biophotonics, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA-directed DNA methylation, Variations
One Comment

Physicists: Desperate Acts Light-induced endogenous RNA interference in bioluminescent microbes links Schrodinger’s claims in “What is LIfe?” (1944) from a light-to-chemical pathway of information exchange in all living genera via amino acid substitutions in supercoiled DNA. All subsequent works on the evolutionary synthesis failed to link  the anti-entropic virucidal energy of sunlight to Darwin’s “conditions of life” from the claims of Schrodinger (1944) or the claims of any other serious scientist. Indeed, in the case of higher animals we know…

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Dobzhansky 1973 and Precision Medicine (2)

January 22, 2017
James Kohl
Adaptations, Alternative Splicings, Diseases & Disorders, Ecology, Model Organisms, Nutrigenomics, RNA Directed, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
One Comment

See also: Dobzhansky 1973 and precision medicine What Did Neanderthals Leave to Modern Humans? Some Surprises A few years ago, the Swedish geneticist Svante Paabo received an unusual fossilized bone fragment from Siberia. He extracted the DNA, sequenced it and realized it was neither human nor Neanderthal. Savante Paabo co-authored this refutation of neo-Darwinian nonsense in 2003.Natural Selection on the Olfactory Receptor Gene Family in Humans and Chimpanzees It links natural selection for energy-dependent codon optimality from the pheromone-controlled physiology…

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Trump’s appeal to common sense (2)

January 20, 2017
James Kohl
Adaptations, Alternative Splicings, Diseases & Disorders, Ecology, Model Organisms, Nutrigenomics, RNA Directed, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations, What's in the News
One Comment

See: Trump’s appeal to common sense Orphan Gpr182 suppresses ERK-mediated intestinal proliferation during regeneration and adenoma formation To our knowledge, this is the first study to use a genetic mouse model to simultaneously map Gpr182 localization patterns and elucidate novel physiological functions for the negative regulation of intestinal proliferative capacity, especially during regeneration and adenoma formation. Future studies to identify the ligand for this exciting and physiologically relevant orphan GPCR [G protein-coupled receptor] will shed light on its tractability as…

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Anti-entropic energy and the “Music of Life”

January 5, 2017
James Kohl
Adaptations, Autophagy, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Neuronal Plasticity, Physics, RNA Directed, RNA-directed DNA methylation, Variations
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TRIM28 Controls a Gene Regulatory Network Based on Endogenous Retroviruses in Human Neural Progenitor Cells … we report the existence of a TRIM28-controlled gene regulatory network based on ERVs that is active in hNPCs. Our findings open up for several exciting future studies on the role of ERVs as potential drivers of human brain evolution, their contribution to individual variation, and the implication in human brain disorders. All gene regulatory networks are energy-dependent. They must link the sun’s anti-entropic virucidal…

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Re-inventing mutation-driven evolution (2)

December 20, 2016
James Kohl
Adaptations, Alternative Splicings, Autophagy, Diseases & Disorders, Ecology, RNA Directed
One Comment

See: Re-inventing mutation-driven evolution See also: Temperature regulates splicing efficiency of the cold-inducible RNA-binding protein gene Cirbp … we suspected that splicing efficiency, as defined by the fraction of pre-mRNA converted into mature mRNA, must have contributed to temperature-dependent Cirbp mRNA accumulation Splicing efficiency is energy-dependent in the context of temperature-dependent oscillations that link the sun’s anti-entropic virucidal energy to all biodiversity via Turing’s claims and my model. See also: The B/Z reaction, and the problem with peer review In…

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Anti-entropic virucidal energy as information

December 18, 2016
James Kohl
Adaptations, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA-directed DNA methylation, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Variations
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 How Can Physics Underlie the Mind? Top-Down Causation in the Human Context by George Ellis (p. 404) Repeated thousands of times over geological timescales, it is this relentless repetition of the top-down process of adaptive selection [29] that gives Darwinian evolution its enormous power. Theorists never seem to ask questions about where the enormous power came from or where it goes when organisms die. They seem to think that relentless repetition of biophysically constrained energy-dependent protein biosynthesis and degradation automagically…

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