ecological adaptation

Bird-brained theorists

December 16, 2016
James Kohl
Adaptations, Ecology, Model Organisms
No Comments

Study: There Are Twice as Many Bird Species as Previously Estimated The issue of biodiversity in all vertebrates was linked from ecological variation to nutrient energy-dependent ecological adaptation by natural selection for codon optimality and differences in morphology paired with differences in behavior in the context of the physiology of reproduction and biophysically constrained cell type differentiation. See: Estrogen receptor α polymorphism in a species with alternative behavioral phenotypes …our results illustrate a detailed chain of events linking a chromosomal…

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Energy-dependent de novo creation and neurogenesis

December 8, 2016
James Kohl
Adaptations, Alternative Splicings, Diseases & Disorders, Ecology, RNA Directed, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
One Comment

See also: Tasting light links energy from creation to adaptation Developmentally defined forebrain circuits regulate appetitive and aversive olfactory learning reported as: When neurons are ‘born’ impacts olfactory behavior in mice My summary: The de novo creation of different cell types is placed into the context of their energy-dependent birth and the transgenerational epigenetic inheritance of molecular mechanisms that link virus-driven energy theft to all pathology via olfaction, food odors, and human pheromones. See for comparison: Metabolism and neurogenesis …it…

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Metabolic Phenotyping Research

December 1, 2016
James Kohl
Adaptations, Diseases & Disorders, Ecology, Physics, RNA Directed, RNA methylation, RNA-directed DNA methylation, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Variations
One Comment

Global Consortium to Conduct Metabolic Phenotyping Research Consortium members in six countries will use chromatography, mass spectrometry, and other technologies to conduct metabolic phenotyping research that examines the dynamic interactions between genes, environments, microbiomes, diets, and lifestyles, and their collective impact on disease. My Predictions. 1. They will link energy as information to healthy longevity. 2. They will report their findings as if they discovered new molecular mechanisms. 3. The mechanisms will link the anti-entropic virucidal energy of ultraviolet light…

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Energy-dependent purifying selection / autophagy (5)

November 21, 2016
James Kohl
Adaptations, Alternative Splicings, Autophagy, Diseases & Disorders, Ecology, Nutrigenomics, RNA Directed, RNA methylation, RNA-directed DNA methylation, Variations
One Comment

See: Energy-dependent purifying selection / autophagy (4) See also: Team develops method to better identify genes involved in diseases If we can pinpoint the genetic mutations that cause a particular disease, we can associate those mutations with specific proteins, and then design drugs to block or activate those proteins. We can also measure the activity of proteins identified in this manner to diagnose diseases more accurately, which is a major goal of precision medicine. In: Histone Acetylome-wide Association Study of…

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Energy-dependent maternal-to-zygotic transition

November 15, 2016
James Kohl
Adaptations, Alternative Splicings, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Neuronal Plasticity, Nutrigenomics, RNA Directed, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
One Comment

Small Non-coding RNAs Associated with Viral Infectious Diseases of Veterinary Importance: Potential Clinical Applications ON 11/14/16 The co-author Mohamed Samir wrote:  Because our article is among the top 25% most viewed and downloaded articles in the third quarter of 2016 in “Frontiers in Veterinary Science”, The editor of the journal has invited me to host and moderate a new research topic in his journal about miRNAs in veterinary filed. Thanks God. The topic is virtually guaranteed to bring out the…

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Virus-driven mutation or amino acid substitution

November 13, 2016
James Kohl
Adaptations, Alternative Splicings, Diseases & Disorders, Ecology, Model Organisms, RNA Directed, RNA methylation, RNA-directed DNA methylation
3 Comments

A computer program just ranked the most influential brain scientists of the modern era Excerpt: “My first thought was, ‘Who could I tell without appearing immodest?’” he said. “I then realized the only people who would want to hear about this are my children!” My comment: Oxytocin-related peptides are 9-13 amino acids long, but they can be recognized in genomic sequences. That allows them to be placed into the context of claims that link the nutrient energy-dependent de novo creation…

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Epigenetics and autophagy vs mutations and evolution

November 10, 2016
James Kohl
Adaptations, Alternative Splicings, biophotonics, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations, What's in the News
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RNA interfernce in “evolution” My comment: What evolved? See for comparison: Energy-dependent RNA-mediated biophysically constrained protein folding chemistry in the context of ecological adaptation.  

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Virus-mediated hecatombic evolution

October 16, 2016
James Kohl
Adaptations, Alternative Splicings, Diseases & Disorders, Ecology, Model Organisms, RNA-directed DNA methylation, Variations
No Comments

Virus-mediated archaeal hecatomb in the deep seafloor These findings provide new evidence for a possible link between viral infections and chemoautotrophic production in the microbial food web. My comment: I hereby stake my claim to the invention of the term”hecatombic evolution.” At the forthcoming meeting of the Royal Society next month, I expect full consideration to be given to use of “hecatombic evolution” to replace neo-Darwinian evolution and/or the “Modern Synthesis” or mutation-driven evolution until everyone in the world realizes…

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Hecatombic evolution via oncocers and oncohistones

October 16, 2016
James Kohl
Adaptations, Alternative Splicings, Autophagy, Diseases & Disorders, Ecology, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
No Comments

Mutation-driven evolution is being replaced by a theory of hecatombic evolution that links oncocers and oncohistones to increasing organismal complexity via autophosphorylation and autophagy or something else as yet to be invented in the context of the new ridiculous theory. See for comparison: Polycomb enables primitive endoderm lineage priming in embryonic stem cells Abstract excerpt: We show that altered transcription is the driver of these coordinated changes, known as lineage priming, in a process that exploits novel polycomb activities. What…

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Hypothesis free pseudoscience vs facts (2)

October 2, 2016
James Kohl
Adaptations, Alternative Splicings, Diseases & Disorders, Ecology, Human Pheromones, Model Organisms, Neuronal Plasticity, Nutrigenomics, Pharmacogenomics, Physics, RNA Directed, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations
One Comment

See first: Hypothesis free pseudoscience vs facts (1) Kondrashov and Kondrashov study shows the complexities of evolution at the mitochondrial tRNA level Conclusion: “As compelling as the step-by-step model of Darwinian evolution is, it seems that at least for stems of mt-tRNAs a majority of substitutions involve population dynamics that allow a population to jump over a short but deep valley in fitness.” My comment: As I recall, de Vries defined “mutation” in the content of sudden jumps in morphological…

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