RNA-Mediated

Adaptations, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA-directed DNA methylation, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Variations

How Can Physics Underlie the Mind? Top-Down Causation in the Human Context by George Ellis (p. 404) Repeated thousands of times over geological timescales, it is this relentless repetition of the top-down process of adaptive selection [29] that gives Darwinian evolution its enormous power. Theorists never seem to ask questions about where the enormous power came from or where it goes when organisms die. They seem to think that relentless repetition of biophysically constrained energy-dependent protein biosynthesis and degradation automagically…

Bird-brained theorists

December 16, 2016

Adaptations, Ecology, Model Organisms

Study: There Are Twice as Many Bird Species as Previously Estimated The issue of biodiversity in all vertebrates was linked from ecological variation to nutrient energy-dependent ecological adaptation by natural selection for codon optimality and differences in morphology paired with differences in behavior in the context of the physiology of reproduction and biophysically constrained cell type differentiation. See: Estrogen receptor α polymorphism in a species with alternative behavioral phenotypes …our results illustrate a detailed chain of events linking a chromosomal…

Energy-dependent de novo creation and neurogenesis

December 8, 2016

Adaptations, Alternative Splicings, Diseases & Disorders, Ecology, RNA Directed, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations

See also: Tasting light links energy from creation to adaptation Developmentally defined forebrain circuits regulate appetitive and aversive olfactory learning reported as: When neurons are ‘born’ impacts olfactory behavior in mice My summary: The de novo creation of different cell types is placed into the context of their energy-dependent birth and the transgenerational epigenetic inheritance of molecular mechanisms that link virus-driven energy theft to all pathology via olfaction, food odors, and human pheromones. See for comparison: Metabolism and neurogenesis …it…

Metabolic Phenotyping Research

December 1, 2016

Adaptations, Diseases & Disorders, Ecology, Physics, RNA Directed, RNA methylation, RNA-directed DNA methylation, RNA-mediated gene silencing, RNA–Mediated Epigenetic Heredity, Variations

Global Consortium to Conduct Metabolic Phenotyping Research Consortium members in six countries will use chromatography, mass spectrometry, and other technologies to conduct metabolic phenotyping research that examines the dynamic interactions between genes, environments, microbiomes, diets, and lifestyles, and their collective impact on disease. My Predictions. 1. They will link energy as information to healthy longevity. 2. They will report their findings as if they discovered new molecular mechanisms. 3. The mechanisms will link the anti-entropic virucidal energy of ultraviolet light…

Energy-dependent purifying selection / autophagy (5)

November 21, 2016

Adaptations, Alternative Splicings, Autophagy, Diseases & Disorders, Ecology, Nutrigenomics, RNA Directed, RNA methylation, RNA-directed DNA methylation, Variations

See: Energy-dependent purifying selection / autophagy (4) See also: Team develops method to better identify genes involved in diseases If we can pinpoint the genetic mutations that cause a particular disease, we can associate those mutations with specific proteins, and then design drugs to block or activate those proteins. We can also measure the activity of proteins identified in this manner to diagnose diseases more accurately, which is a major goal of precision medicine. In: Histone Acetylome-wide Association Study of…

Energy-dependent maternal-to-zygotic transition

November 15, 2016

Adaptations, Alternative Splicings, Diseases & Disorders, Ecology, Light Energy, Model Organisms, Neuronal Plasticity, Nutrigenomics, RNA Directed, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations

Small Non-coding RNAs Associated with Viral Infectious Diseases of Veterinary Importance: Potential Clinical Applications ON 11/14/16 The co-author Mohamed Samir wrote: Because our article is among the top 25% most viewed and downloaded articles in the third quarter of 2016 in “Frontiers in Veterinary Science”, The editor of the journal has invited me to host and moderate a new research topic in his journal about miRNAs in veterinary filed. Thanks God. The topic is virtually guaranteed to bring out the…

Virus-driven mutation or amino acid substitution

November 13, 2016

Adaptations, Alternative Splicings, Diseases & Disorders, Ecology, Model Organisms, RNA Directed, RNA methylation, RNA-directed DNA methylation

3 Comments

A computer program just ranked the most influential brain scientists of the modern era Excerpt: “My first thought was, ‘Who could I tell without appearing immodest?’” he said. “I then realized the only people who would want to hear about this are my children!” My comment: Oxytocin-related peptides are 9-13 amino acids long, but they can be recognized in genomic sequences. That allows them to be placed into the context of claims that link the nutrient energy-dependent de novo creation…

Epigenetics and autophagy vs mutations and evolution

November 10, 2016

Adaptations, Alternative Splicings, biophotonics, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, Model Organisms, Neuronal Plasticity, Nutrigenomics, Physics, RNA Directed, RNA methylation, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA-mediated gene silencing, RNA-mediated toxicity, RNA–Mediated Epigenetic Heredity, Variations, What's in the News

RNA interfernce in “evolution” My comment: What evolved? See for comparison: Energy-dependent RNA-mediated biophysically constrained protein folding chemistry in the context of ecological adaptation.

Virus-mediated hecatombic evolution

October 16, 2016

Adaptations, Alternative Splicings, Diseases & Disorders, Ecology, Model Organisms, RNA-directed DNA methylation, Variations