RNA-Mediated

Dedicated to Dr. Tom Jordan and Priscilla Jordan on the day of their retirement from the Baptist ministry, May 28, 2017. They always encouraged me to learn more about the “Laws of Biology” and link the Laws from energy as information to all biodiversity on Earth via the physiology of reproduction. See also: From E. coli to monkeys and mankind: Theories vs models High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding (5/23/127) …changes in observed association…

Food energy-dependent epigenetic adaptation (3)

May 25, 2017

Adaptations, Ecology, Light Energy, Model Organisms, Physics, RNA Directed, Variations

Food energy-dependent epigenetic adaptation (2) On 5/24/17 I attempted to post this to the ISHE’s human ethology group in response to the post on How concepts of God have developed: God’s shrinking role. God’s survival. Conclusions. For comparison, see the expanding role of anti-entropic virucidal energy that theorists claim automagically emerged to sustain all evolved biodiversity. I included a link to: I also included a link to: The moderator of the group responded quickly: Jay R. Feierman wrote: What you…

Food energy-dependent epigenetic adaptation (2)

May 24, 2017

Adaptations, Alternative Splicings, Cytosis, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, Model Organisms, Physics, RNA-directed DNA methylation, RNA–Mediated Epigenetic Heredity, Variations

Due to the overwhelming support for my model of top-down causation and all energy-dependent biophysically constrained biodiversity on Earth, I will replace Food energy-dependent epigenetic adaptation (2) with the more appropriately titled God’s shrinking role in your salvation See: Food energy-dependent epigenetic adaptation and God’s shrinking role in your salvation (in prep) before proceeding to the rest of this series on epigenetic adaptation.

Food energy-dependent epigenetic adaptation

May 24, 2017

Adaptations, biophotonics, Diseases & Disorders, Ecology, Human Pheromones, Light Energy, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA interference, RNA methylation, RNA-directed DNA methylation, RNA-mediated gene silencing, Variations

Mechanism of transmembrane signaling by sensor histidine kinases, was reported as Scientists investigate how the sense of smell works in bacteria …the signaling and inactive states differ only very slightly at the nitrate-binding site – by 0.5-1 angstroms, which is approximately one fifth of the size of the ion itself (1 angstrom is 10-10 meters). However, when this ion binds to the sensor, it causes huge changes in the protein: The helices of different monomers begin to move in different…

Energy-dependent epigenetic translation to mRNA stability (6)

May 22, 2017

Adaptations, biophotonics, Cytosis, Diseases & Disorders, Ecology, Human Brain, Human Pheromones, Light Energy, Model Organisms, Nutrigenomics, Physics, RNA Directed, RNA-directed DNA methylation, RNA-mediated epigenetic regulation of gene expression, RNA–Mediated Epigenetic Heredity, Variations

See: Energy-dependent epigenetic translation to mRNA stability (5) Five energy-dependent amino acid substitutions are linked to differences in RNA content and biodiversity in 4 mammalian species. Excerpt: Species- and tissue-specific variation in mt-tRNA incorporation into the mt-LSU was analyzed…. Analysis of porcine dermal fibroblasts (C), human osteosarcoma 143B cells (D), bovine cardiac tissue (E), and rat hepatic tissue (F) depicts the relative abundance of each mt-tRNA across fractions (ImageQuant software); represented as a percentage of the total signal. In my…

Energy-dependent epigenetic translation to mRNA stability (4)

May 16, 2017

Adaptations, Autophagy, Diseases & Disorders, Ecology, Physics, RNA Directed, RNA-directed DNA methylation

See first: Energy-dependent epigenetic translation to mRNA stability (3) First-ever direct observation of chiral currents in quantum Hall atomic simulation The report on the simulation fails to address the facts about what happens at the level of hydrogen-atom transfer in DNA base pairs in solution when you have an MRI. Perhaps the link from chirality to autophagy and all cell type differentiation in all living genera is not obvious. See: Magnetic resonance imaging MRI is based upon the science…

Energy-dependent epigenetic translation to mRNA stability (3)

May 15, 2017

Adaptations, Diseases & Disorders, Ecology, Model Organisms, RNA Directed, RNA-directed DNA methylation, RNA–Mediated Epigenetic Heredity, Variations

Energy-dependent epigenetic translation to mRNA stability (2) Energy-dependent epigenetic translation to mRNA stability (2) See for comparison this treatise on climate change packaged as information on the evolution of a flying snake. Fossil ‘winged serpent’ is a new species of ancient snake At the time that Zilantophis dwelled there, the site was a sinkhole surrounded by forest, attracting a variety of animals. The local fauna included ancient representatives of familiar North American creatures such as bears, beavers and salamanders. Others…

The death of human ethology via ecology

May 3, 2017

Adaptations, Cytosis, Diseases & Disorders, Ecology, Model Organisms, RNA Directed, Variations

Nutrient-dependent/pheromone-controlled adaptive evolution: a model Open access publication on June 14, 2013 Mutation-driven evolution also published on June 14, 2013 Variable habitat conditions drive species covariation in the human microbiota http://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1005435 Open access publication on April 27, 2017 Conclusion: …we found that genetically related species respond to fluctuating habitat conditions in the same way, implying that they occupy similar ecological niches. Thus, current taxonomic groupings of bacteria are largely sufficient for explaining cross-sectional correlations in relative species abundances over the…

The Virus-Driven Suicide March for Science

April 24, 2017

Adaptations, biophotonics, Diseases & Disorders, Ecology, Model Organisms, Nutrigenomics, Pharmacogenomics, RNA Directed, RNA-directed DNA methylation, Variations

Genetic analysis of α-synuclein 3′ untranslated region and its corresponding microRNAs in relation to Parkinson’s compared to dementia with Lewy bodies My summary: Genetic predispositions and energy-dependent microRNA biogenesis link top-down causation to the biophysically constrained transgenerational epigenetic inheritance of neuronal type-specific expression. Energy-dependent variability in endogenous RNA interference and the SNCA gene contribute to synucleinopathies in the context of two different human pathologies. Virus-driven energy theft is linked to the regulation of the α-synuclein (SNCA) gene and the etiology…

Theistic evolutionists fight back and lose (2)

February 27, 2017