#SFN2019 to 2012: Hiding the facts (2)

Polycomb repressive complex 1: Regulators of neurogenesis from embryonic to adult stage extends our 1996 claims in From Fertilization to Adult Sexual Behavior to all ethnic diversity in morphology and behavior via alternative splicings of pre-mRNAs. The term use began to change from pre-mRNAs to microRNAs. I learned that from the abstract of a presentation #SFN2019 to 2012: Hiding the facts (2)

Light-activated continuous environmental tracking (1)

New imaging techniques have linked The Art of Building Small, from molecular switches to motors (2016 video) and cryo electron microscopy (cryo-EM) from light-activated microRNA biogenesis to energy-dependent changes in angstroms and ecosystems in my model of biophysically constrained viral latency. See: Nucleotide Modification Alters MicroRNA-Dependent Silencing of MicroRNA Switches 12/18/18 link opens pdf Abstract excerpt: MicroRNA Light-activated continuous environmental tracking (1)

Vulgar Antagonists vs Quantum Effects

Exosome Cargo Could Be Drug Target For Neuropathic Pain My discussion attempt was removed by Dfm Prime, who claims to be a patient advocate for those who are suffering from neurological insult. See: Works at Neurosensory Neuroregenerative Research Foundation Publication: Catechol-O-Methyl Transferase Inhibition Reduces Symptoms of Hallucinogen Persisting Perception Disorder See for comparison: Oppositional COMT Vulgar Antagonists vs Quantum Effects

Energy-dependent physical and biophysical constraints (5)

Summary: Emmy Noethe’s theorems were developed in the early 1900’s. Richard Feynman inadvertently or purposefully alluded to them as examples of human idiocy. Discover Magazine resurrected the examples of human idiocy in a 2017 article. For comparison, Choi et al., (2017) support the claims that intercellular and interkingdom communication is energy-dependent and controlled by the Energy-dependent physical and biophysical constraints (5)

Energy-dependent hydrogen bonds in supercoiled DNA

Chirality Check Most biological macromolecules are homochiral, and enzymes help to maintain this state of affairs; for example, checkpoints ensure that only l-amino acids are incorporated into proteins during translation. The fixation of the only achiral amino acid, glycine in position 6 of the gonadotropin releasing hormone decapeptide protein links the nutrient energy-dependent pheromone-controlled physiology Energy-dependent hydrogen bonds in supercoiled DNA

Bird-brained theorists

Study: There Are Twice as Many Bird Species as Previously Estimated The issue of biodiversity in all vertebrates was linked from ecological variation to nutrient energy-dependent ecological adaptation by natural selection for codon optimality and differences in morphology paired with differences in behavior in the context of the physiology of reproduction and biophysically constrained cell Bird-brained theorists

Energy-dependent de novo creation and neurogenesis

See also: Tasting light links energy from creation to adaptation Developmentally defined forebrain circuits regulate appetitive and aversive olfactory learning reported as: When neurons are ‘born’ impacts olfactory behavior in mice My summary: The de novo creation of different cell types is placed into the context of their energy-dependent birth and the transgenerational epigenetic inheritance Energy-dependent de novo creation and neurogenesis

Theories vs facts about polycombic adaptation

See: Demoncrats fight polycombic ecological adaptation Exosomes as miRNA Carriers: Formation–Function–Future Important aspects will be highlighted as a take-home message (THM) at the end of each paragraph. THM: Extracellular vesicles transport miRNA in a paracrine and endocrine manner. Questions regarding the cellular options of producing either microvesicles or exosomes and their difference in miRNA composition Theories vs facts about polycombic adaptation