Organic Compounds and the Miracle of Smell and Taste

Neo-Darwian evolutionary theorists and human ethologists seem to ignore the fact that reproductive isolation is nutrient-dependent and controlled by the physiology of reproduction. …reproductive isolation may sometimes follow and at other times precede the adaptive divergence of gene pools of populations. — Dobzhansky (1972) Those who cite Dobzhansky’s (1973)  claim that Nothing in Biology Makes Any Sense Except in the Light of Evolution, have failed to explain why …the so-called alpha chains of hemoglobin have identical sequences of amino acids…

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Life history transitions and RNA-mediated survial

The Endospore-Forming Pathogen Bacillus cereus Exploits a Small Colony Variant-Based Diversification Strategy in Response to Aminoglycoside Exposure Conclusion:  Thus, consideration of SCVs as a new, yet unexplored lifestyle of B. cereus within the common ecological niches, in which antibiotic-active substances produced by competitive microorganisms, plants, and invertebrate/vertebrate vectors might potentially also induce this persistent life-form of B. cereus, opens a panoply of research questions to be followed up. Reported as: Lifestyle switching – Bacillus cereus is able to resist certain antibiotic therapies…

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MicroRNA-encoded behavior

MicroRNA-encoded behavior in Drosophila Editor’s summary: MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene activity. They repress expression through complementary base pairing interactions with target messenger RNAs… My comment: If I were going to link biophysically constrained nutrient-dependent protein folding chemistry to biodiversity, I would start with nutrient energy-dependent base pair changes and link microbes to humans via the conserved molecular mechanisms of their epigenetically-effected RNA-mediated metabolic networks and genetic networks. For example, I would link vitamin C to…

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Skip the politics; embrace the facts

It’s Not Brain Surgery, Ben Carson Excerpt: …“Heal Inspire Revive,” invokes an image of him pounding on the chest of a pulseless America. Whether or not he actually knows how to handle a crash cart of that size, many voters don’t seem to doubt that he can. And he doesn’t doubt it either. My comment: I do not expect anyone who understands what is currently known about how physics and chemistry are linked to the biophysically constrained conserved molecular mechanisms…

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700 million years of evolution?

Analysis of 5′ gene regions reveals extraordinary conservation of novel non-coding sequences in a wide range of animals Conclusion: It is our hope that each and every one of these regions will make interesting candidates for experimental analysis, helping to increase our understanding of regulation of gene expression, and particularly our understanding of regulatory elements in RNA. My comment: In other words, they hope what has already been detailed in the context of how nutrient-dependent microRNAs link the epigenetic landscape…

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Preventing genomic entropy

Tethering Transposons Excerpt: Transposons—thought to be related to viruses—can copy themselves and insert randomly around the genome. A paper published today (October 15) in Science provides a greater understanding of how cells shut down these rogue jumping genes. My comment: Shouldn’t someone else be claiming that nutrient-dependent microRNAs prevent the accumulation of viral microRNAs that leads to perturbed protein folding, which links mutations to all pathology in the context of an atoms to ecosystems model? Nutrient-dependent pheromone-controlled ecological adaptations: from atoms…

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Foundamentals of theory

There are foundations of epigenetics and fundamentals of molecular mechanisms. They have been detailed in this atoms to ecosystems model of RNA-mediated cell type differentiation. Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems. I have never seen anyone mention the “foundamentals” of epigenetics. It appears the word has been invented. Similarly, the word “mutation” was invented in 1904 by de Vries. Inventing words and defining them to fit ridiculous theories about neo-Darwinian evolution is required to continue convincing theorists that…

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Alternative pre-mRNA splicing and ecological adaptation

This startup thinks it can speed up a cure for cancer by bringing scientific research into the YouTube era Excerpt: The current scholarly publishing model did not allow me to present the research I was doing. I created [Figshare] initially out of purely selfish reasons and I spent my evenings and weekends creating a platform that allowed me show, in a super simple way, data sets, and videos to put me ahead of the rest of my peers. I’ve used…

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Anti-entropic containment of energy: symbiosis 1.0

Scientists explore the origins of energy in chemical reactions using experimental quantum chemistry Excerpt: One thing that all chemical reactions have in common—whether they are the reactions that take place inside a battery, the metabolic reactions inside a living organism, or the combustion reactions that cause an explosion—is that they all involve some kind of change in energy. My comment: Therein lies the problem with attempts by pseudosceintists to link nutrient energy from ecological variation to epigenetically-effected ecological adaptation, which…

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Becoming biologically informed (3)

See also: Becoming biologically informed and Becoming biologically informed (2) Now available for free: New Perspectives on microRNA in Disease and Therapy (July 22, 2015) My comments: Perhaps someone will correct me if I am wrong. The microRNAs do not appear to participate in a direct response to viruses. But, over long periods of time they may fine-tune the microRNA/messenger RNA balance in the organized genomes of all living genera.  If so, the changes are manifested in morphology and in…

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  • Randomness and Divine Providence
    A Q&A on randomness and God’s providence …the main goal is to really put together a collection of scholarly studies of these issues: physicists, biologists, […]