EDAR V370A

Quantum Darwinism (3)

“Quantum biology” is quantum Darwinism Starting from…discovery of quantum coherence in low-temperature photosynthetic microbes in 2007, quantum coherence is emerging as a general principle of biological systems. See: MicroRNAs organize intrinsic variation into stem cell states 3/5/20 …naturally arising cell-to-cell variation, sometimes described as stochastic fluctuation, is in fact coherently organized biology. Theorists chose neo-Darwinian pseudoscientific nonsense about beneficial mutations and evolution via natural selection across billions to millions of years instead of the explanatory power of quantum Darwinism. Their ignorance…

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Protonated RNA interference vs stupid theories (6)

These two articles appeared at the top of a list of 300+ more when I searched PubMed search for “protonated RNA interference” on 11/20/20 Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells 10/24/20 The ATPase ATP6V1A facilitates rabies virus replication by promoting virion uncoating and interacting with the viral matrix protein 11/18/20 Taken together, they link the molecular mechanisms of hydrogen- and water-dependent biophysically constrained viral latency to proton beam therapy for cancer or to virus-driven pathology…

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Protonated RNA interference vs stupid theories (2)

Protonated RNA interference vs stupid theories (1) Evidence for Hidden Involvement of N3-Protonated Guanine in RNA Structure and Function 1/31/19 Charged nucleobases have been found to occur in several known RNA molecules and are considered essential for their structure and function. Estimating Strengths of Individual Hydrogen Bonds in RNA Base Pairs: Toward a Consensus between Different Computational Approaches 4/30/19 Noncoding RNA molecules are composed of a large variety of noncanonical base pairs that shape up their functionally competent folded structures.…

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Vaccines do not control pandemics (1)

See: Emergence of Human G2P[4] Rotaviruses in the Post-vaccination Era in South Korea: Footprints of Multiple Interspecies Re-assortment Events 4/16/18 Compared to the G2 RotaTeq vaccine strain, 17-24 amino acid changes, specifically A87T, D96N, S213D, and S242N substitutions in G2 epitopes, were observed. Amino acid changes control pandemics. Congo: MSF Ebola vaccination begins 5/30/18 The Ebola vaccine (rVSVDG-ZEBOV-GP) is being used as part of the overall strategy to control the Ebola outbreak. There was no indication that the vaccine strategy…

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The eternal significance of microRNAs and the Vietnam Memorial (1)

Researchers who believe in the mutation-driven evolution of species and mutation-driven differences in human populations have invented another ridiculous hypothesis. Now, they believe in mathematical models that infer: Cultural hitchhiking and competition between patrilineal kin groups explain the post-Neolithic Y-chromosome bottleneck In human populations, changes in genetic variation are driven not only by genetic processes, but can also arise from cultural or social changes. An abrupt population bottleneck specific to human males has been inferred across several Old World (Africa,…

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Epigenetic inheritance of spatiotemporal regulation (3)

Summary: Wen Zhou’s group has linked the creation of anti-entropic virucidal light from the quantized energy-dependent creation of microRNAs to the food energy-dependent neuroendocrine origins of human behavior via the pheromone-controlled physiology of reproduction and fixation of RNA-mediated amino acid substitutions in species from microbes to humans. Simply put, she has linked quantum physics to quantum souls via what is known about biophysically constrained viral latency in the context of the cell biology game Cytosis and the future of biology.…

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The eternal significance of microRNAs (5)

Excerpt: Researchers in South Korea, for example, have reminded the God-less Communist dictator of North Korea that one microRNA-mediated amino acid substitution in the influenza B virus could decimate the human populations that he thinks he rules. Conclusion: Conserved energy biophysically constrains viral latency. Ridiculously ignorant objections to my publication in what others claim is a predatory journal can be compared to my objection to publication of this article in PNAS. Environmental selection during the last ice age on the…

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A single base change refutes theistic evolution

Everyone who failed to learn how light-activated endogenous substrates biophysically constrain viral latency is playing “catch up” to serious scientists. The serious scientists know how quantized energy-dependent RNA-mediated cell type differentiation occurs in the context of the physiology of reproduction in all living genera. Rather than accept the fact that the innate immune system of bacteria (CRISPR) linked the pheromone-controlled physiology of reproduction from autophagy to biophysically constrained viral latency, theorists decided to waste money on virus-assisted gene-editing attempts to…

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Environmental selection is natural selection

Environmental selection during the last ice age on the mother-to-infant transmission of vitamin D and fatty acids through breast milk was published on April 23, 2018 The ectodysplasin A receptor (EDAR) gene has a range of pleiotropic effects, including sweat gland density, incisor shoveling, and mammary gland ductal branching. The frequency of the human-specific EDAR V370A allele appears to be uniquely elevated in North and East Asian and New World populations due to a bout of positive selection likely to…

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An evolutionary theory killer

MicroRNA-mediated denuclearization (6)

Summary: The EDAR V370A isoform links one quantized energy-dependent base pair change from changes in ultraviolet light (UV) exposure to fixation of one amino acid substitution. The substitution differentiates the cell types of mice and humans in the context of a mouse-to-human model of nutritional epigenetics and microRNA-mediated denuclearization in North Korea. Environmental selection during the last ice age on the mother-to-infant transmission of vitamin D and fatty acids through breast milk …a genetically isolated population living in this environment…

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