enzyme

Criticisms of a validated model

Microglia Turnover in the Human Brain “With electron microscopy, we find a variety of immune cells in the brain, especially in contexts of disease,” she writes. Richard Feynman predicted this in the context of a lecture on nanotechnology. He presciently placed cryo-EM into the context of a lecture about Plenty of Room at the Bottom. Examination at this level of observable energy-dependent top-down causation has since linked the sun’s anti-entropic virucidal energy from hydrogen-atom transfer in DNA base pairs in…

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Automagical protein creation sans energy

Summary: The creation of the enzyme is linked to the evolution of all biodiversity via the creation of the enzyme and mutations. See for comparison: Neuronal-expressed microRNA-targeted pseudogenes compete with coding genes in the human brain. Listen to this song about Santa Claus and note that he sees you when you’re sleeping and somehow unconsciously determines if you’ve been good or bad. Santa Claus may know that the sense of smell has repeatedly been linked to effects on hormones and unconscious…

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RNA-guided gene editing

From June 14, 2015 Light induced RNA-mediated gene activation Eye-independent, light-activated chromatophore expansion (LACE) and expression of phototransduction genes in the skin of Octopus bimaculoides Energy-dependent RNA-mediated prevention of heart failure Small-molecule activation of SERCA2a SUMOylation for the treatment of heart failure Theoretical pseudoscientific nonsense Ancient DNA reveals how Europeans developed light skin and lactose tolerance Energy dependent RNA-mediated brain development Scientists find genetic underpinnings of functional brain networks seen in imaging studies More pseudoscientific nonsense Scientists show future events…

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Origin of life and cancer (1,2,3)

1) On the Origins of Life The physics of the light-induced de novo creation of the amino acids was placed into the context of  ‘cyanosulfidic’ protometabolic systems chemistry. The systems chemistry links substitution of achiral glycine in the gonadotropin releasing hormone (GnRH) decapeptide to the biophysically constrained nutrient dependent RNA-mediated chemistry of protein folding in all vertebrates. The role of food odors and hormone-controlled cell type differentiation in all vertebrates also links changes in the balance of viral microRNAs and…

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De novo gene Creation sans evolution of genes via mutations

Where do genes come from? – Carl Zimmer The pseudoscientific nonsense touted in this video has been refuted by decades of experimental evidence. The experimental evidence links RNA-directed DNA methylation from nutrient-dependent amino acid substitutions to the de novo Creation of olfactory receptor genes and fixation of amino acid substitutions in the DNA of organized genomes. Fixation occurs via the nutrient-dependent pheromone-controlled physiology of reproduction in species from microbes to man. Evolution: Dynamics of De Novo Gene Emergence “…it was…

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