epigenetic effects

An evolutionary theory killer

A single base change refutes theistic evolution (2)

Announcing publication of a model that links the creation of quantized energy from changes in subatomic particles to biophysically constrained viral latency and sympatric speciation in all living genera. Nutrient-dependent Pheromone-Controlled Ecological Adaptations: From Angstroms to Ecosystems This angstroms to ecosystems model of ecological adaptation links nutrient energy-dependent epigenetic effects on base pairs and amino acid substitutions to pheromone-controlled changes in the microRNA/messenger RNA balance and chromosomal rearrangements via the physiology of reproduction in species from microbes to humans. The…

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From base editing to RNA editing (2)

Summary: The link from the creation of the sun’s anti-entropic virucidal energy and the physiology of pheromone-controlled reproduction to fixation of RNA-mediated amino acid substitutions in the organized genomes of all living genera is all that is required to claim adaptation for comparison to Koonin’s moronic assertion that the amino acid composition of proteins varies because the composition evolved. Digital reconstruction of the Ceprano calvarium (Italy), and implications for its interpretation A “fresh” (i.e., not yet “fossil”) bone can be…

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Evolutionary theories of epigenetic drift

Testing Two Evolutionary Theories of Human Aging with DNA Methylation Data My summary: Outside the context of food energy-dependent biophysically constrained pheromone-controlled viral latency, mutation accumulation (MA) and disposable soma (DS) provide possible explanations for the existence of human aging. For example, age-differentially-methylated sites across the genome showed significant MA-consistent increases in heritability with age or significant DS-consistent decreases in heritability. Their results supposedly show that both MA and DS play a role in explaining aging and aging-related changes but…

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Inventing “Transcriptome Trajectory Turning Points”

Summary: They invented the term “Transcriptome Trajectory Turning Points” to prevent others from learning that virus-driven energy theft is the cause of all pathology. Scientists discover genetic timetable of brain’s aging process The biggest reorganisation of genes occurs during young adulthood, peaking around age 26, the team found. These changes affected the same genes that are associated with schizophrenia. The team says this could explain why people with schizophrenia do not show symptoms until young adulthood, even though the genetic…

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Epigenetic effects of stress by Bruce McEwen (2)

Summary: …rapid mRNA turnover starts with the energy-dependent de novo creation of microRNAs and ends with the virus-driven degradation of messenger RNA, which links mutations to all pathology.   This was reported in the following context: “RNA molecules live short lives” July 12, 2017 See also: Epigenetic effects of stress by Bruce McEwen (1) Summary: In the early 1990’s, Bruce McEwen inspired my life’s works, which link the epigenetic effects of nutrient-stress and/or social stress to the fact that RNA biosynthesis…

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Energy-dependent microRNA biogenesis

Published May 3, 2017 Genetic variation and RNA structure regulate microRNA biogenesis …primary sequence determinants and RNA structure are key regulators of miRNA biogenesis. Genetic variation aka primary sequence determinants are energy-dependent and RNA-mediated. Energy-dependent RNA methylation is an experience-dependent link from natural selection for energy-dependent codon optimality. Natural selection for energy-dependent codon optimality links ATP-dependent microRNA biogenesis to RNA biosynthesis. Ridiculous attempts to portray energy-dependent top-down causation as if genetic variation came first may continue for another 52 years.…

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Cytosis: Biology Content

  Help Me Write Some Biology Content Project Update #5: Cytosis: A Cell Biology Board Game by John Coveyou (Genius Games) Many of you have mentioned that you’d like to have an explanation of the biology behind Cytosis available… and I think that is an AWESOME plan. Every time I’ve taught the game to non-science players in the past, they say gameplay made even more sense (and was so much more enjoyable) when I explained the science as well. This…

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Biologically uninformed biologists fight back and lose

Novel layers of RNA polymerase III control affecting tRNA gene transcription in eukaryotes 22 Feb 2017 A subset of tRNA genes shows low responsiveness to both environmental and cellular signals. Notably, this group contains at least one tRNA for each amino acid. Together these findings suggest the existence of a basal subset of housekeeping tRNA genes [36]. This concept is consistent with the mode of Maf1-mediated repression of actively transcribed tRNA genes in human cells subjected to serum starvation [104].…

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Science journalists or paid propagandists? (2)

See: Science journalists or paid propagandists? Excerpt: Riffell is interested in how chemical signals, like smells, affect behavior. Explore further: Researchers show that the mosquito smells, before it sees, a host. This was reported last year in “Science” and on January 6, 2017 as Orchids mimic human body odor to attract mosquitoes The year-long delay aroused my suspicion because everything known to serious scientists since 1996 has linked food odors and pheromones to reproduction in species from microbes to humans.…

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2016 obfuscated facts about energy as information

Illumination of the fluorescent biomarker in green revealed that the adult mouse brain could be infected by Zika in a region called the subgranular zone of the hippocampus. Full of neural progenitor cells, this part of the brain is important in learning and memory. Credit: Laboratory of Pediatric Brain Disease at The Rockefeller University/Cell Stem Cell As reported by Bob Yirka in: Best of Last Year – The top Medical Xpress articles of 2016 a team of MIT biologists reported…

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