epigenetics

Molecular Diagnostics: What is unprotected life? (2)

See also: Molecular Diagnostics: What is unprotected life? What is life when it is not protected from virus driven entropy Published on 30 Mar 2016. Presentated at Molecular Diagnostics on April 6 and 7, 2016 The poster also is available at Figshare POSTER (abstract) “The anti-entropic force of virucidal ultraviolet (UV) light links guanine–cytosine (G⋅C) Watson–Crick base pairing from hydrogen-atom transfer in DNA base pairs in solution to supercoiled DNA, which protects the organized genomes of all living genera from…

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Nutrient-dependent life vs virus-driven pathology

Young Earth Creationists killing Christian credibility? Perry Marshall says: March 19, 2016 at 10:04 am James, you are one step away from being banned because of your disingenuous comments, your accusations, and your unnecessary combativeness. I am getting tired of it. People accuse you of being a troll for a reason. This is your final warning. My comment: Thanks for the warning, Perry Marshall. People who do not like me to disseminate accurate information about biologically-based cause and effect accuse…

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RNA-mediated theory killers (11) (12) (13) (14) (15)

Historical perspective Scent of a Book Deal (1995) Excerpt: The search for love the second time around can sometimes lead to scientific as well as romantic inspiration. At least, that’s what happened to James Vaughn Kohl, coauthor of the recently published volume The Scent of Eros (New York, Continuum Publishing Co., 1995). In a press release accompanying the book, Kohl-who manages a clinical laboratory for a group of physicians at Partell Medical Center in Las Vegas-writes, “My scientific interest in…

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Epigenetic (re)programming of behavior (3)

Bipolar drug turns foraging ants into scouts Excerpt: “DNA methylation has become nearly synonymous with epigenetics,” says Brendan Hunt, an insect geneticist at the University of Georgia in Griffin. “This research brings needed attention to the importance of other epigenetics marks, like histone modifications.” “We finally have a mechanism to understand ‘nurture’ in molecular terms,” says Gene Robinson, a geneticist at the University of Illinois, Urbana-Champaign, who studies caste determination in honey bees. The ant study, he adds, highlights “how…

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Stress-perturbed mitochondrial dysfunction

Mitochondrial functions modulate neuroendocrine, metabolic, inflammatory, and transcriptional responses to acute psychological stress Excerpt: To visualize the stress-reactive profiles across genotypes, a heat map with hierarchical clustering of the mean relative difference “stress–resting” was generated, demonstrating that each mitochondrial defect induced a different amino acid response signature (Fig. 4F). In particular, the stress-reactive amino acid profile was most distinct in mice with the respiratory chain complex I ND6 defect. To determine which class of amino acids was most discriminatory between…

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Neo-Darwinian logic is nonsense

Let’s discover how we humans created the concept of God for our own survival throughout evolution Months of irrelevant banter with no intelligent response to details that I provided with links to what is currently known about biophysically constrained protein folding led to this exchange: WEENY: “…all changes to gene sequences are currently called mutations.” JVK: What need is there for anyone to call them “mutations” except when linking them from virus-driven genomic entropy to pathology? Why not simply tell…

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RNA Mediated

Metaphysical science vs theory

I’ve wasted too much time attempting to explain biologically-based facts to the biologically uninformed discussants on Science X network. This is an attempt to salvage some of the time and to move forward.  See: New comments posted on Science X network: – A natural history of neurons: Diverse mutations reveal lineage of brain cells : 1 new comment – Study sheds light on powerful process that turns food into energy : 1 new comment – Study adds to evidence that…

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Information and communication (2)

Leaving an Imprint Among the first to discover epigenetic reprogramming during mammalian development, Wolf Reik has been studying the dynamics of the epigenome for 30 years. By Anna Azvolinsky | August 1, 2015 Excerpt: In the mammalian field, the imprinting field, together with the X-inactivation field, was the birthplace of epigenetics. My comment: Researchers like Wolf Reik never mentioned the role viruses play in preventing cell type differentiation. The birthplace of epigenetics became associated with a “still-birth.” The still-birth continued to…

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An unprecedented view of genomic complexity

Scientists develop more accurate whole genome variant discovery and interpretation Excerpt: “The study revealed an unprecedented view of genomic complexity, in many cases identifying regions overlooked by conventional sequencing or further refining previously known genetic variant classes…. “We had notable success in challenging regions such as inversions and tandem repeats… a systematic underrepresentation of tandem repeat sizes was observed in the human reference genomes. Such expansions, as we observed within the LPA gene which has been associated with plasmid lipid…

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“First” evidence

First evidence of how parents’ lives could change children’s DNA 17:00 04 June 2015 by Helen Thomson Excerpts: Surani’s team analysed methylation patterns in a type of fetal cell that later forms a fetus’s own sperm or eggs. We would expect these cells to have been wiped clean when the fetus’s epigenome was reset at the early embryo stage. “However, about 2 to 5 per cent of methylation across the genome escaped this reprogramming,” says Surani. Marcus Pembrey, emeritus professor…

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