ethology

The eternal significance of microRNAs (1)

Common Allele Linked to Sugar Consumption Leads to Lower Body Fat, Higher Blood Pressure One energy-dependent change in a base pair is linked from the FGF21 rs838133 variant to microRNA-mediated changes in morphology and behavior. The quantized energy as information link from microRNAs to morphology and behavior is common to my mouse-to-human model of sympatric speciation. By linking the common allele to sugar consumption, the authors attest to the fact that sympatric speciation is quantized energy-dependent. Energy as information biophysically constrains…

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Sympatric Speciation vs pseudosceintific nonsense (4)

The energy-dependent creation of ATP synthase and the energy-dependent creation of the microRNA repertoire have now been linked to biophysically constrained RNA-mediated sympatric speciation via the innate immune system in species from Axolotyls to A. davidianus infected with ranavirus. MicroRNA repertoire and comparative analysis of Andrias davidianus infected with ranavirus using deep sequencing MicroRNA mediated host-pathogen interactions are important in antiviral defense. See: Meet the creature that can regenerate its brain and resist cancer. (video) Identification and characterization of the…

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A null mutation and healthy longevity?

Summary: Food odors and pheromones biophysically constrain all pathology in species from microbes to humans. What kind of biologically uninformed science idiot leaves out everything known to serious scientists about the virus-driven degradation of messenger RNA and tells others they must falsify the neutral null theory that led to claims about a biophysically constrained beneficial “null mutation” in the Amish population of Berne, Indiana? Glutamylation Regulates Transport, Specializes Function, and Sculpts the Structure of Cilia Reported as: How to Control…

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For God and Country

Dispelling the ignorance of theorists

American Legion Riders (Riding for God and Country on 9/9/17) Summary: The highest-order of energy-dependent pre-assembly of respiratory chain complexes allows mitochondria to respond to energy-requiring conditions. There is no such thing as the emergence of energy, self-assembly, self-organization or any other pseudoscientific nonsense touted by theorists. Their theories exemplify what Richard P. Feynman referred to as “human idiocy.” That is why I refer to theorists who argue with me as “biologically uninformed science idiots.” Friends sometimes tell me I…

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God vs host-derived creation of virus-driven pathology

Summary: The virus-driven theft of quantized energy forces cells to compete for nutrient energy-dependent RNA-mediated reprogramming in the context of the structure of photons, one-carbon metabolism, autophagy, and the physiology of reproduction, which links energy-dependent changes in chirality from base pairs to RNA-mediated amino acid substitutions. Host-derived viral transporter protein for nitrogen uptake in infected marine phytoplankton (with my emphasis) Viruses often carry genes acquired from their host. In the present work, we show that a virus of a marine…

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Energy-dependent self-organization and self repair

Energy-dependent autophagy links food odors and pheromones from the innate immune system and RNA-mediated feedback loops to the physiology of reproduction in all living genera via chromosomal inheritance. Transgenerational epigenetic inheritance is nutrient-energy-dependent and pheromone-controlled. That fact has been established in the extant literature since 1933, when Thomas Hunt Morgan won the Nobel Prize in Medicine, and Erwin Schrodinger shared the 1933 Prize in Physics with Paul A.M. Dirac. See for example: From Fertilization to Adult Sexual Behavior December 1996…

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Did evolution autophosphorylate your kinases? (2)

Hecatombic evolution Deep-Sea Viruses Destroy Archaea Excerpt: Given the enormous scale of deep-sea ecosystems, the results indicate that archaea-virus relationships could be a major contributor to global biogeochemical cycles. My comment:  I know that Anna Di Cosmo​ and John Hewitt​ are able to link virus-driven energy theft to all pathology in all living genera via the conserved molecular mechanisms they have already placed into their proper perspective on natural selection for energy-dependent codon optimality, which links the innate immune system…

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The tipping point? 50, 000 publications (2)

Pubmed.com “microRNA” Hedgehog signaling enables nutrition-responsive inhibition of an alternative morph in a polyphenic beetle Excerpt: Significance Complex, nongradual responses to environmental conditions are commonplace in nature and perhaps most extreme in polyphenic insects where continuous variation in nutrition experienced in early development gives rise to discrete alternative castes or morphs. This research shows that the hedgehog (Hh) pathway has acquired a novel and highly unusual role in the nutrition-dependent regulation of polyphenic development of a beetle. Experimental repression of…

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