Eugene Koonin

Complexity: Routes and Patterns (1)

Physical foundations of biological complexity  “Routes and patterns of the evolution of complexity are poorly understood.” Serious scientists have linked differences in the competing energy of two photons from the proton motive force to biophysically constrained viral latency via the physiology of pheromone-controlled reproduction in species from microbes to humans. Ages 10+ can learn how serious scientists did this by playing the cell biology game “Cytosis.” It starts from the creation of the sun’s anti-entropic virucidal energy and links it…

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A null mutation and healthy longevity?

Summary: Food odors and pheromones biophysically constrain all pathology in species from microbes to humans. What kind of biologically uninformed science idiot leaves out everything known to serious scientists about the virus-driven degradation of messenger RNA and tells others they must falsify the neutral null theory that led to claims about a biophysically constrained beneficial “null mutation” in the Amish population of Berne, Indiana? Glutamylation Regulates Transport, Specializes Function, and Sculpts the Structure of Cilia Reported as: How to Control…

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From base editing to RNA editing (2)

Summary: The link from the creation of the sun’s anti-entropic virucidal energy and the physiology of pheromone-controlled reproduction to fixation of RNA-mediated amino acid substitutions in the organized genomes of all living genera is all that is required to claim adaptation for comparison to Koonin’s moronic assertion that the amino acid composition of proteins varies because the composition evolved. Digital reconstruction of the Ceprano calvarium (Italy), and implications for its interpretation A “fresh” (i.e., not yet “fossil”) bone can be…

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Your indifference is killing you and others

Summary: Coherence-inducing mechanisms is double-speak for mechanisms that are nutrient-dependent and pheromone-controlled. Feedback loops link odor and pheromone signaling with reproduction has been presented in double-speak as Looplessness in networks is linked to trophic coherence We are currently studying the entropy of the coherence ensemble we defined for this work. “In general, higher trophic coherence would be associated with lower entropy states, which means that if networks are more coherent than the random expectation there must indeed be some kind…

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Your indifference is killing you and others (2)

Two family members and two close friends are among those who have unfriended me on Facebook. Like the late Carl Woese and Eugene Koonin, they are not willing to examine any of the facts about energy-dependent RNA-mediated cell type differentiation. I have never asked anyone to do that until after they have claimed or inferred that my facts are wrong or that the facts do not prove anything. At that point, their indifference is what causes more unnecessary suffering and…

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Energy-dependent physical and biophysical constraints (10)

Summary: The entire evolution of the microbial world and the virus world, and the interaction between microbes and viruses and other life forms have been left out of the Modern Synthesis…— Eugene Koonin My comment: Viruses are not life forms. They steal the quantized energy that links sunlight to viral latency in the context of everything known to all serious scientists about the fact that Feedback loops link odor and pheromone signaling with reproduction See for comparison: Olfaction Warps Visual…

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Happy Darwin Day (2017)

My series of blog posts about the refutation of theistic evolution by George Church led him to contact me via email. He asked why he would get credit for or against the refutations He claimed he was trained in quantum physics. He claimed that he has authored peer reviewed papers on protein folding, biodiversity, supercoiling, etc. He wanted to know more but did not know enough about my target audience to realize why I included information about the viral hecatomb.…

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Light ‘drives’ adaptation; nothing ‘drives’ evolution (2)

See: Light ‘drives’ adaptation; nothing ‘drives’ evolution See also: Who rules the waves? – Viruses might just be bit players in the drama of the seas. Then again, they could be major actors Excerpt (from 1996):  Most consider viruses to be a legion of cripples, sterilised by ultraviolet radiation and rendered impotent by hosts that are largely immune to their threat. But a few researchers take the opposite view. And if they turn out to be right, viruses could radically…

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DNA repair via junk DNA (2)

See also: DNA repair via junk DNA (1) Recently Evolved Genes Identified From Drosophila yakuba and D. erecta Accessory Gland Expressed Sequence Tags (2006) Reported in Singer (2015) as: In 2006, Begun found some of the first evidence that genes could indeed pop into existence from noncoding DNA. Singer’s claim that genes automagically pop into existence is consistent with Masatoshi Nei’s conclusion in: Mutation-Driven Evolution …genomic conservation and constraint-breaking mutation is the ultimate source of all biological innovations and the…

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From nothing to life and death everywhere

Astronomers in South Africa discover mysterious alignment of black holes Excerpt 1) This implies that there is a coherent spin in the structure of this volume of space that was formed from the primordial mass fluctuations that seeded the creation of the large-scale structure of the universe. Excerpt 2) “This is not obviously expected based on our current understanding of cosmology. It’s a bizarre finding.” Excerpt 3) A large-scale spin distribution has never been predicted by theories – and an…

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