evolution

Conceptual critique: Innateness vs the death gene (1)

Summary: The term innate is used in psychological explanations. The so-called explanations ignore facts about the light energy-dependent activation of endogenous substrates. The anti-entropic virucidal energy of sunlight links the endogenous substrates to biophysically constrained viral latency and healthy longevity via the physiology of reproduction in all living genera. “Proximate mechanisms” and “evolution” are terms used by biologically uninformed theorists. That fact becomes perfectly clear in the context of  The conceptual critique of innateness (paywalled) One proposal is that innateness can…

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An evolutionary theory killer

A reversible TCA cycle in a thermophile (3)

A pathway for mitotic chromosome formation The combination of nested loops distributed around a helically twisted axis plus dense chromatin packing achieves the 10,000-fold compaction of chromatin into linearly organized chromosomes that is required for accurate chromosome segregation when cells divide. The compaction of chromatin in the context of hydrophobicity is the topic of: Structural diversity of supercoiled DNA Our data provide relative comparisons of supercoiling-dependent twisted, writhed, curved, and kinked conformations and associated base exposure. Each of these structural…

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Anti-entropic sunlight: Schrödinger’s Creationist Secret? (4)

Summary: Antagonists such as John Hewitt have exhausted my patience. Now see this: The authors invented the term “phosphate steering”  in an attempt to obfuscate what has been known to all serious scientists about oxidative phosphorylation for more than 50 years. See: “oxidative phosphorylation” microRNA  (105 entries); “oxidative phosphorylation” (21955 entries) and “phosphate steering” (1 entry) Compare the nonsense about phosphae steering to facts in the context of Modern diversification of the amino acid repertoire driven by oxygen (2017) published…

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The MicroRNAome Strikes Back: A Sokalian hoax (1)

Summary: How can this not be a Sokalian hoax? The creation of sunlight is not linked to anti-entropic virucidal energy-dependent  cell-type-specific epigenetic modifications. The quantized energy-dependent epigenetic modifications include RNA-directed DNA methylation, histone modification, nucleosome remodeling and higher-order chromatin reorganization. Instead, the magic of non-cell autonomous DNA methylation in plants is placed into in the context of the cytosine residue in CG, CHG and CHH sequence contexts (where H represents A, T or C). See for comparison: Analysis of 6,515 exomes reveals…

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Autophagy is the antiphage defense strategy (2)

2/15/17 Energy as information and constrained endogenous RNA interference (video) The 6.46 minute-long technical presentation (above) from the Precision Medicine Virtual Conference is difficult to understand.Thus, 10 months later, Nik Willmore asked: 12/24/17 What are your insights into CRISPR and mTOR, for a young audience? I’m not mocking you…yet, Humpty Dumpty. What is the basis of your unifying principle? Vibration? Bohmian morphogenetic fields? Modified Darwin? God? –Nik Willmore @nikwillmore 12/25/17 Replying to @nikwillmore @jhewitt123 God created the anti-entropic virucidal energy of sunlight and…

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From Autophagy.pro (transitions)

Summary: Who lets biologically uninformed theorists make presumptions about evolution after all serious scientists have linked light-harvesting from energy-dependent changes in electrons to ecosystems in all living genera via natural selection for food energy-dependent codon optimality. Who lets them pretend not to know that the pheromone-controlled physiology of reproduction links autophagy to the transgenerational epigenetic inheritance of healthy longevity? Who is causing the unnecessary suffering and premature death of your loved ones? Elsevier publishing supports the pseudoscientific nonsense touted by…

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Mouse morphs and primate diversity in 50 years

Excerpt: Analysis of the crystal structure of deer mouse Hb at 1.8 Å resolution (24, 25) revealed that each of the eight rHb mutants is characterized by a unique constellation of hydrogen bonds within and between subunits (Table 2 and fig. S2). Additional hydrogen bonds between subunits of the same αβ dimer are formed in the presence of β128Ser (an L-type residue; fig. S2), which contributes to the observed epistasis between allelic α- and β-chain variants. ——————————— Energy-dependent RNA-mediated biophysically…

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Reporting new scientific truths is not allowed in the USA (2)

Summary: Genetic mutations do not drive evolution.  Energy-dependent RNA-mediated fixation of amino acid substitutions links the physiology of reproduction to biophysically constrained viral latency. With minimal effort, you can peruse the science news each day to see how many pseudoscientists report their findings outside the context of food energy-dependent pheromone-controlled biophysically constrained RNA-mediated cell type differentiation. See for example: Type 2 diabetes has hepatic origins The researchers are now working on identifying the endogenous ligand produced by the body, or…

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From base editing to RNA editing (2)

Summary: The link from the creation of the sun’s anti-entropic virucidal energy and the physiology of pheromone-controlled reproduction to fixation of RNA-mediated amino acid substitutions in the organized genomes of all living genera is all that is required to claim adaptation for comparison to Koonin’s moronic assertion that the amino acid composition of proteins varies because the composition evolved. Digital reconstruction of the Ceprano calvarium (Italy), and implications for its interpretation A “fresh” (i.e., not yet “fossil”) bone can be…

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For God and Country

Energy-dependent structure and function: Until death (5)

Summary: If a player starts with evolution instead of the creation of energy that links ATP to the creation of RNA, the player is a loser. Nobody wants to belong to the party of losers. One of the best strategies in such a case is evidently an interpretation of the change as a gradual accumulation of knowledge while their work has always been at the cutting edge. — Kalevi Kull Secular: Ancient Viruses Are Buried in Your DNA (2017) by…

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