experimental evidence

From nitrogen atoms to ecosystems in all living genera

Summary: The “tiny machines” that “massacre viruses” link the creation of the anti-entropic virucidal energy of sunlight to the pheromone-controlled physiology of reproduction in all living genera via the nitrogen-dependent weekend resurrection of the bacterial flagellum in P. fluorescens. See: Virus-mediated archaeal hecatomb in the deep seafloor We show here for the first time the crucial role of viruses in controlling archaeal dynamics and therefore the functioning of deep-sea ecosystems, and suggest that virus-archaea interactions play a central role in…

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Virus-driven energy theft and premature death

See also: Energy is information, RNA interference and healthy longevity Mitochondria operate as signaling platforms in yeast aging Aging is obviously energy-dependent. Theorists do not seem to know where the energy comes from or how genomic entropy is prevented.  For the most recent example of what some researchers don’t know, see: Yeast mutants unlock the secrets of aging By confirming that there are active mechanisms limiting the longevity of any organism, we provided the first experimental evidence that such lifespan-limiting…

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Energy-dependent oscillating gene networks organize life

Nascent, innate, intrinsic, and biofunctional are among the “weasel words” used by theorists who ignore the fact that all life-sustaining energy comes from the sun via hydrogen-atom transfer in DNA base pairs in solution. See how Jon Lieff continues to misrepresent that fact, by placing everything known about RNA-mediated cell type differentiation back into the context of evolution. Like all pseudoscientists, he starts with energy but fails to mention where the energy came from or where it goes when virus-driven…

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Happy biophysically constrained Thanksgiving (in the USA)

Is there any other holiday in the world that celebrates biophysically constrained cell type differentiation in all living genera? The availability of amino acids and proteins in new genes is nutrient energy-dependent. The de novo creation of genes is biophysically constrained by the innate immune system and the physiology of reproduction. That fact was detailed for a general audience in Biblical Genesis. Today, all of us can be thankful that the pseudoscientific nonsense of neo-Darwinian theory was replaced earlier in…

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80 years of causal analysis (1936 – 2016)

Roles of Mutation and Selection in Speciation: From Hugo de Vries [1902 definition of mutation] to the Modern Genomic Era Excerpt: …mutation is crucial in speciation because reproductive barriers cannot be generated without mutations. My comment: Chromosomal rearrangements link autophagy from energy-dependent changes in RNA-mediated amino acid substitutions and supercoiled DNA to all biodiversity via speciation. Some Principles of Causal Analysis in Genetics (1936) Extract: …high frequency radiation and particles of high velocity are very important components of the environment,…

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Hypothesis free pseudoscience vs facts (4)

See first Hypothesis free pseudoscience vs facts (3) See also: The terrorist inside my husband’s brain Conclusion: I know you have accomplished much already in the areas of research and discovery toward cures in brain disease. And I am sure at times the progress has felt painfully slow. Do not give up. Trust that a cascade of cures and discovery is imminent in all areas of brain disease and you will be a part of making that happen. If only…

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Energy-dependent cellular communication

Communication shapes sensory response in multicellular networks Significance Cells routinely sense and respond to their environment, and they also communicate with each other. Exactly how communication impacts sensing remains poorly understood. We study a population of fibroblast cells that responds to a chemical stimulus (ATP) and communicates by molecule exchange. Combining experiments and mathematical modeling, we find that cells exhibit calcium oscillations in response to not only the ATP stimulus but also, increased cell–cell communication. Our results show that, when…

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Hydrogen-atom transfer in DNA base pairs (5)

Can Anybody Actually Win The Evolution 2.0 Prize? January 18, 2016 at 9:44 pm In an invited review of nutritional epigenetics, I linked atoms to ecosystems without the pseudoscientific nonsense touted by neo-Darwinists. Kohl, James V. (2014): Nutrient-dependent pheromone-controlled ecological adaptations: from atoms to ecosystems. The invited submission was returned without review. When I provide all the details for the origin of the DNA code, what prevents the submission from being rejected without comment? January 18, 2016 at 11:13 pm …

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Viruses come alive: Tree of life pseudoscience

See also: The creation and activation of GPCRs ‘Tree of life’ for 2.3 million species released This comment was removed from a “tree of life” discussion site by the “site staff.” In the context of anonymous “peer” review, the comment was removed for the following reason: PSEUDOSCIENCE, with an added threat that my account might be suspended in case of regular violations of the guidelines that led the “site staff” to remove this comment. Young earth creationists addressed the “Tree…

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Rs3827760 is Val370Ala and EDARV370A

Introduction: A Single Nucleotide Polymorphism (SNP) is a DNA sequence variation in which a single nucleotide — A, T, C or G — in the genome (or other shared sequence) differs between members of a biological species or paired chromosomes. SNPs within a coding sequence do not necessarily change the amino acid sequence of the protein that is produced. Rs3827760 is Val370Ala Excerpt: …Val370Ala, is a SNP in the ectodysplasin A receptor EDAR gene on chromosome 2. The EDAR gene…

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