Fescue Toxicosis

Virus-driven reduction of RNA polymerase II occupancy in hosts (2)

See: Virus-driven reduction of RNA polymerase II occupancy in hosts (1) See: Genome-Wide Study Reveals a Novel Regulatory Pathway: Translation Affects mRNA Stability in a Codon-Dependent Manner (On Demand Webinar 6/26/19) This webinar outlines a study that combined genome-wide and classical molecular approaches to demonstrate that translation strongly affects mRNA stability in a codon-dependent manner, Virus-driven reduction of RNA polymerase II occupancy in hosts (2)

The tipping point (revisited): 86,000 publications

“Darwin had a huge data set and no mechanism—where would he publish today? This is a problem!” — Arturo Casadevall Darwin’s light-activated “conditions of life” are microRNA-mediated. The mechanisms have been exquisitely detailed n ~86,000 indexed publications. Light-activated microRNA biogenesis in plants links the sudden appearance of flowering plants from his “abominable mystery” to the genesis The tipping point (revisited): 86,000 publications

Energy-dependent structure and function: Until death (3)

For God and Country

Energy-dependent structure and function: Until death (2) The COMT Val158Met polymorphism supposedly is not found in species other than humans See: Global variation in the frequencies of functionally different catechol-O-methyltransferase alleles This is also the first study establishing the COMT*L allele as the derived allele unique to humans. Other organisms do not commit suicide. That Energy-dependent structure and function: Until death (3)

Energy-dependent structure and function: Until death (2)

For God and Country

Energy-dependent structure and function: Until death (1) Terry Crews details alleged sexual assault by ‘high level’ Hollywood exec “This whole thing with Harvey Weinstein is giving me PTSD. Why? Because this kind of thing happened to ME…” Crews tweeted Tuesday. This claim helps to link the celebrity status of Hollywood victims like Robin Williams to Energy-dependent structure and function: Until death (2)

Energy-dependent structure and function: Until death (1)

For God and Country

The structure-energy landscape of NMDA receptor gating …using single-molecule Forster resonance energy transfer (smFRET), we map the energy landscape of the first transmembrane segment of the Rattus norvegicus NMDA receptor under resting and various liganded conditions. These results show kinetically and structurally distinct changes associated with apo, agonist-bound, and inhibited receptors linked by a linear Energy-dependent structure and function: Until death (1)

Methylation and the Innate Immune System

Free Webinar Training: Methylation and the Innate Immune System Free Training: Methylation and the Innate Immune System Please send your questions, comments and feedback to: support@qahomestudy.com I sent these two questions in advance: 1) Does what organisms eat link food energy to RNA-directed DNA methylation and all healthy longevity via fixation of amino acid substitutions Methylation and the Innate Immune System

Bringing RNA back to epigenetics (20 years later)

Has Contemporary Academia Outgrown the Carl Sagan Effect?  [Subscription required] Excerpt (with my emphasis): [Sean Carroll] offered 13 pieces of advice…: “Do good research; Make an impact in the field; Bring in grant money… Don’t be too well known outside the field; Don’t write a book; Choose your hobbies wisely.” Carroll argued that academics look Bringing RNA back to epigenetics (20 years later)