G protein-coupled receptor

The tipping point (revisited): 84,000 publications (2)

The tipping point (revisited): 84,000 publications (1) Attempts to discuss facts with liberals are a waste of time. They cannot believe that gun violence linked to school shootings is caused by the failed transition from adolescence to adulthood, which can be predicted by non-invasive measurement of the COMT Val158Met allele. Dr. Sean Gallagher‏ wrote “Huh” The tipping point (revisited): 84,000 publications (2)

The MicroRNAome Strikes Back: A Sokalian hoax (5)

https://nnjournal.net/article/viewFile/2354/1850/10234

Premise: Sunlight is the quantized energy as information that is required to link endogenous RNA interference to healthy longevity (The energy-dependent creation of microRNAs links the physiology of reproduction from changes in electrons to ecosystems in all living genera via the creation of ATP, RNA, and supercoiled DNA in organized genomes.) Counter claim:  The Quantum The MicroRNAome Strikes Back: A Sokalian hoax (5)

1996-2016: Ignoring alternative splicings of pre-mRNA

Range of diseases may result when brain self-regulation goes awry, researchers say There is no such thing as self-regulation of the brain. Regulation is food energy-dependent and biophysically constrained by changes in the microRNA/messenger RNA balance. The entire range of diseases is linked from the virus-driven degradation of messenger RNA to the mutations that some 1996-2016: Ignoring alternative splicings of pre-mRNA

Dispelling the ignorance of theorists

For God and Country

American Legion Riders (Riding for God and Country on 9/9/17) Summary: The highest-order of energy-dependent pre-assembly of respiratory chain complexes allows mitochondria to respond to energy-requiring conditions. There is no such thing as the emergence of energy, self-assembly, self-organization or any other pseudoscientific nonsense touted by theorists. Their theories exemplify what Richard P. Feynman referred Dispelling the ignorance of theorists

Synthetic RNA-based switches

Synthetic RNA-based switches for mammalian gene expression control Current Opinion in Biotechnology, Volume 48, December 2017, Pages 54–60 If you wait until December, 2017 to see this article in print, you will probably be among the last of those to have missed a two decades-old paradigm shift. The fact that these researchers created synthetic RNA-based Synthetic RNA-based switches

RNA methylation (2)

Conditioning as an adjunct in the pharmacotherapy of lupus erythematosus Several studies have provided evidence suggesting that “placebo effects” represent conditioning phenomena and that learning processes influence the response to placebo medication. This case report describes an adolescent with severe lupus erythematosus who received cyclophosphamide (CY) paired with taste (cod liver oil) and smell (rose RNA methylation (2)

Amino acid substitutions, stress, and human behavior

Stress dynamically regulates behavior and glutamatergic gene expression in hippocampus by opening a window of epigenetic plasticity Excerpt: …33% of the human population present a BDNF Val66Met SNP that leads to a valine-to-methionine substitution in the BDNF protein at codon 66, and this SNP has been associated with increased susceptibility to development of stress-related disorders Amino acid substitutions, stress, and human behavior