G-protein-coupled receptors

Exposing the 2nd Law to more ridicule (1)

Summary: Experiment demonstrates quantum mechanical effects from biological system Schrödinger (1944) linked the anti-entropic virucidal energy of sunlight from the physiology of pheromone-controlled reproduction in soil bacteria to all biodiversity. He then began to suspect that his colleagues, who displayed human idiocy, would kill him – if ever again he reasserted the facts. After 1944, Richard P. Feynman took a stand against the human idiocy, and lost. He was not killed, just ignored. Ignorance prevails. It always has. The virus-driven…

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Long-term adaptation replaces evolution (2)

The food energy-dependent “doubling up” on ‘junk DNA’ is biophysically constrained by the physiology of pheromone-controlled reproduction. The metabolism of food to species-specific pheromones links the conserved molecular mechanisms of RNA-mediated cell type differentiation in all individuals of all living genera to healthy longevity via what is known about amino acid substitutions in supercoiled DNA, which link energy-dependent changes in chirality to autophagy. Supercoiled DNA is far more dynamic than the ‘Watson-Crick’ double … Researchers have imaged in unprecedented detail the…

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Lethal virus kills 5 billion people?

Until death: Virus-driven failure of multisensory integration (2)

Summary: The virus-driven degradation of messenger RNA is clearly linked to frontotemporal dementia (FTD) by altered language, personality, behavior, cognition and motor function. What causes FTD? If the virus-driven degradation of messenger RNA causes all pathology, I would expect to find a link from microRNAs to the pathology and to the effective treatment. The social and economic burden of frontotemporal degeneration Reported as: Study reveals staggering economic burden of dementia in younger people Frontotemporal degeneration (FTD) accounts for 20 to…

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Predicting who wins the 2017 Nobel Prizes (5)

Summary: If he was not still dead, the 1965 Nobel Laureate, Richard P. Feynman might claim that this year’s Physics Prize was awarded for “human idiocy.” Nobel Prize in Physics Awarded to LIGO Black Hole Researchers Einstein’s General Theory of Relativity, pronounced in 1916, suggested that matter and energy would warp the geometry of space-time the way a heavy sleeper sags a mattress, producing the effect we call gravity. His equations described a universe in which space and time were…

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Optogenetics replaces fMRI but not pseudoscientific nonsense

Summary: The ability to evaluate spaciotemporal influences on health compared to virus-driven pathology must include a link from quantized energy to the creation of ATP and the creation of RNA. Hunting people down who are aware of that fact is difficult because most of them have ignored the facts from this 1964 publication. Ed Boyden and Optogenetics: The Future of Neuroscience (video) (transcript) What I’m trying to do now is see whether we can help people pilot crazy projects that…

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Energy-dependent physical and biophysical constraints (9)

Summary: Energy determines genome compaction because activity in the nucleus is energy-dependent. Chromatin chains link energy-dependent changes in base pairs from single nucleotide polymorphisms to fixation of RNA-mediated amino acid substitutions in organized genomes via the physiology of pheromone-controlled reproduction. It’s all about the base. Energy-dependent physical and biophysical constraints (8) ChromEMT: Visualizing 3D chromatin structure and compaction in interphase and mitotic cells Excerpt 1) The chromatin structure of DNA determines genome compaction and activity in the nucleus. My comment:…

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Energy-dependent epigenetic translation to mRNA stability (4)

See first: Energy-dependent epigenetic translation to mRNA stability (3) First-ever direct observation of chiral currents in quantum Hall atomic simulation The report on the simulation fails to address the facts about what happens at the level of hydrogen-atom transfer in DNA base pairs in solution when you have an MRI. Perhaps the link from chirality to autophagy and all cell type differentiation in all living genera is not obvious.   See: Magnetic resonance imaging MRI is based upon the science…

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Emily Witkin refutes theistic evolution

February 21, 2017 The SOS Response in Bacteria Her professor/advisor was Theodosius Dobzhansky. She watched as Barbara McClintock indirectly linked the tobacco mosaic virus from Thomas Hunt Morgan’s work on chromosomal inheritance, and she helped link virus-driven energy theft to all biodiversity via experimental evidence of DNA repair. Now that the structure and function of supercoiled DNA has linked the effects of sunlight to all biodiversity via the physiology of pheromone-controlled reproduction in species from bacteria to humans, why does…

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George Church refutes theistic evolution (2)

See: George Church refutes theistic evolution George Church may not know that he refuted every aspect of theistic evolution in his presentation on February 8, 2017. Hopefully, someone will tell him how he linked quantum physics from chemistry to biophysically constrained protein folding and all biodiversity, or explain to others how he did that. Here is my explanation of his admissions. I placed the explanation into the context of this poster session submission. Title: Energy as information and constrained endogenous…

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Energy as information and constrained endogenous RNA interference (2)

Precision Medicine virtual conference, Feburary 22-23, 2017 This abstract has been accepted for presentation as a poster. Title: Energy as information and constrained endogenous RNA interference  James V. Kohl RNA-mediated.com jvkohl@bellsouth.net Abstract describing the poster Abstract: Feedback loops link quantized energy as information to biophysically constrained RNA-mediated protein folding chemistry.  Light induced energy-dependent changes link  angstroms to ecosystems from classical physics to chemistry/chirality and to molecular epigenetics/autophagy. The National Microbiome Initiative links microbial quorum sensing  to the physiology of reproduction…

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