genetic code

microRNA-mediated election cycles (7)

Are multi-quasiparticle interactions important in molecular ionization? 3/28/21 GWΓ [calculations] offers a unified description across all relevant energy scales. Our results suggest that the multi-QP regime corresponds to dynamical correlations, which can be described via perturbation theory. Few intelligent serious scientists understand the complexities of calculations needed to link God’s Creation of energy-as- information to biophysically constrained viral latency and healthy longevity across kingdoms. Most of them know what happens when a paradigm fails. Pseudoscientists know when they got stuck…

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Biologically uninformed science idiot: Self-defense (2)

Summary: “Construction of automata” is the operative phrase. But you must be willing to believe that the automata create themselves outside the context of the creation of sunlight and light-activated endogenous substrates in all cell types of all living genera. Causation, constructors and codes A formal definition of codes in general, and organic codes in particular, allows the relational diagram to be extended so as to capture this translation of formal cause into process. The extended relational diagram is used…

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Anti-entropic sunlight: Schrödinger’s Creationist Secret? (4)

Summary: Antagonists such as John Hewitt have exhausted my patience. Now see this: The authors invented the term “phosphate steering”  in an attempt to obfuscate what has been known to all serious scientists about oxidative phosphorylation for more than 50 years. See: “oxidative phosphorylation” microRNA  (105 entries); “oxidative phosphorylation” (21955 entries) and “phosphate steering” (1 entry) Compare the nonsense about phosphae steering to facts in the context of Modern diversification of the amino acid repertoire driven by oxygen (2017) published…

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What is life without sunshine?

Summary: It seems likely that Schrodinger’s anti-entropic virucidal effect of sunlight will be linked to the RNA-mediated de novo creation of all organized genomes and the maintenance of the “spotless epigenome” in this presentation later today. If so, even theorists and other pseudoscientists who planned to “March for Science” will finally be seen in the context of Dobzhansky’s claims about the “…light of evolution.” Erasing Epigenetic Marks: Eternal Sunshine of the Spotless Epigenome Topics to be covered: The variety of…

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Tasting light links energy from creation to adaptation

The C. elegans Taste Receptor Homolog LITE-1 Is a Photoreceptor “In Brief: A taste receptor homolog absorbs UV light and mediates avoidance behavior in C. elegans in response to light exposure.” Excerpt: Light sensation is critical for all phyla of life, ranging from bacteria to humans (Wang and Montell, 2007; Yau and Hardie, 2009). Organisms have evolved various types of photoreceptor proteins… Photoreceptors are G protein-coupled receptors (GPCRs). No experimental evidence of biologically-based cause and effect links the evolution of any…

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Epigenetics and autophagy vs mutations and evolution (8)

Mycobacterial RNA isolation optimized for non-coding RNA: high fidelity isolation of 5S rRNA from Mycobacterium bovis BCG reveals novel post-transcriptional processing and a complete spectrum of modified ribonucleosides. Epub 2014/12/30 Abstract except:   This optimized RNA isolation procedure thus provides a means to more rigorously explore the biology of ncRNA species in mycobacteria. Reported 2016/11/11 in the context of: Newly discovered genetic code controls bacterial survival during infections Excerpt: “It is really an alternative genetic code, in which any gene…

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Epigenetics and autophagy vs mutations and evolution (7)

RNA interference (RNAi) fails to protect all cell types from virus-driven energy theft. The effect on some cell types cannot be controlled. That’s because nutrient energy-dependent endogenosymbiosis and the pheromones-controlled physiology of reproduction protect the organized genomes of species from microbes to humans. Billions of waster dollars have been spent with no end to the waste in sight — until the Trump administration stops it. As that begins to happen, see: tRNA-mediated codon-biased translation in mycobacterial hypoxic persistence (open access)…

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Biophotonics, glycobiology, quantized biodiversity (2)

From Fertilization to Adult Sexual Behavior (1996) In our section on Molecular epigenetics, we wrote: Small intranuclear proteins also participate in generating alternative splicing techniques of pre-mRNA and, by this mechanism, contribute to sexual differentiation in at least two species, Drosophila melanogaster and Caenorhabditis elegans (Adler and Hajduk, 1994; de Bono, Zarkower, and Hodgkin, 1995; Ge, Zuo, and Manley, 1991; Green, 1991; Parkhurst and Meneely, 1994; Wilkins, 1995; Wolfner, 1988). That similar proteins perform functions in humans suggests the possibility…

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Origin and evolution of the genetic code

Origin and evolution of the genetic code: the universal enigma Excerpt: …it appears essentially certain that the evolution of the code involved some combination of frozen accident with selection for error minimization. My comment: This claim from 2009 failed to address anything currently known to serious scientists about the Schrodinger’s claim from 1944, in What is Life? Indeed, in the case of higher animals we know the kind of orderliness they feed upon well enough, viz. the extremely well-ordered state…

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