genetic processes

Codon optimality vs systemic fraud (4)

A good model predicts. See: From Fertilization to Adult Sexual Behavior (1996). In our section on molecular epigenetics we predicted that A chemoenzymatic strategy for site-selective functionalization of native peptides and proteins 6/16/22 would be linked to food energy and pheromone-regulated genetic processes of reproduction across kingdoms. On 6/23/22, that fact was placed back into the context of stupid theories. See: Abracadabra, One Becomes Two: The Importance of Context in Viral −1 Programmed Ribosomal Frameshifting  Yeast and potentially mammalian cells,…

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RNAi 2002 to AI 2021 (8)

Prebiotic amino acids bind to and stabilize prebiotic fatty acid membranes 8/12/19 To test whether the inclusion of amino acids addresses this problem, we coupled direct techniques of cryoelectron microscopy and fluorescence microscopy Reported as:  First cells may have emerged because building blocks of proteins stabilized membranes 8/12/19 The stability of membranes is hydrogen-bond (pH) dependent. Nothing known to intelligent serious scientists about top-down causation suggests that stability of cell membranes automagically emerged. See for comparison:  microRNA More than 133,000…

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microRNA-mediated cures (1)

See first: Naturally attenuated viral endemicity (10) All effective cancer therapies and drug therapies are energy-dependent and microRNA-mediated. Princeton team disables long-targeted gene behind spread of major cancers 11/29/21 This discovery has its roots in 2004 research in which Princeton scientists identified a gene implicated in metastatic breast cancer, called metadherin, or MTDH. Prevent obfuscation of facts that link energy-dependent changes in single nucleotide polymorphisms (SNPs) in microRNAs to all effective cancer treatments via the RBP-noncoding RNA regulation network. Read:…

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Naturally attenuated viral endemicity (4)

Peptide synthesis at the origin of life 11/13/20 and Visualizing a protonated RNA state that modulates microRNA-21 maturation 10/26/20 link the ATP-dependent Creation of RNA 9/11/64 to …protection of the skin of P. azureus adults against increased O2 levels and UV exposure on land compared with aquatic environments. See: The peptide secreted at the water to land transition in a model amphibian has antioxidant effects 11/10/21 …PaT-2 is the first peptide expressed during the ontogeny of P. azureus, right before the…

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Naturally attenuated viral endemicity (1)

microRNA 130,014 results The importance of naturally attenuated SARS-CoV-2in the fight against COVID-19 (4/28/20) and other virus-driven diseases was published less than one week after former President Trump clearly stated that sunlight and humidity kill coronaviruses. See also: Imagination and remembrance: what role should historical epidemiology play in a world bewitched by mathematical modelling of COVID-19 and other epidemics? 6/7/21 …every established respiratory pandemic of the last 130 years has caused seasonal waves of infection and has culminated in viral…

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Quantum Darwinism (6)

Learn how sunlight and humidity link photosynthesis from construction of the cell wall  to biophysically constrained viral latency via God’s ATP-dependent Creation of RNA.   For links from the light-activated assembly of the microRNA-RNA-peptide nanocomplex across kingdoms via the Creation of enzymes see: Castration increases and androgens decrease nitric oxide synthase activity in the brain: physiologic implications (2000) and Differentiation of Human Induced Pluripotent or Embryonic Stem Cells Decreases the DNA Damage Repair by Homologous Recombination (2017) The nitric oxide…

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Quantum Darwinism (1)

See first: Pheromones protect us from viruses parts 1-10 For a historical perspective on the development of healthy ecosystems, see: Pheromonal Regulation of Genetic Processes: Research on the House Mouse (Mus musculus L.) (1994) and From Fertilization to Adult Sexual Behavior (1996) For links from quantum Darwinism to all energy-dependent biophysically constrained biodiversity, see also: Quantum Criticality at the Origin of Life 3/3/15 The number of proteins grows exponentially with the number n of amino acids… Peptide synthesis at the…

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Pheromones protect us from viruses (1)

Involvement of transposable elements in neurogenesis 3/24/20 appeared in my search for indexed articles that mention microRNA on 3/4/21. There are more than 116,500 others. See: microRNA  MicroRNAs, many of which arise from transposon transcripts, also play an important role in regulating the differentiation of neuronal stem cells. That fact was established in the mid-1990s and was linked From Fertilization to Adult Sexual Behavior (1996) via pre-mRNA-mediated stem cell differentiation across kingdoms in our section on molecular epigenetics. At that time…

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Impeaching the God of Abraham (1)

2/10/21 Researchers who share the Abrahamic faiths have refuted the pseudoscientific nonsense touted by all atheists. See: microRNA 115, 376 results There are currently 1052 results for microRNA and Israel 2,063 results for microRNA and Iran 2414 results for microRNA and Korea For a historical perspective on what is known to all intelligent serious scientists about biophysically constrained viral latency across kingdoms see the references from: Regulation of host and virus genes by neuronal miR-138 favours herpes simplex virus 1…

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Protonated RNA interference vs stupid theories (6)

These two articles appeared at the top of a list of 300+ more when I searched PubMed search for “protonated RNA interference” on 11/20/20 Identification of Required Host Factors for SARS-CoV-2 Infection in Human Cells 10/24/20 The ATPase ATP6V1A facilitates rabies virus replication by promoting virion uncoating and interacting with the viral matrix protein 11/18/20 Taken together, they link the molecular mechanisms of hydrogen- and water-dependent biophysically constrained viral latency to proton beam therapy for cancer or to virus-driven pathology…

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